Development Level

Tbio 91 | 10,625
Tdark 26 | 7,003
Tchem 16 | 1,890

IMPC Term

preweaning lethality, complete... 11 | 633
hyperactivity 5 | 108
abnormal behavior 4 | 226
decreased lean body mass 4 | 195
abnormal behavioral response t... 3 | 52
abnormal bone structure 3 | 131
abnormal embryo size 3 | 112
abnormal sleep behavior 3 | 63
increased circulating alkaline... 3 | 119
increased circulating sodium l... 3 | 71
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
abnormal coat/hair pigmentatio... 2 | 54
abnormal placenta size 2 | 10
absent pinna reflex 2 | 21
convulsive seizures 2 | 11
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased grip strength 2 | 123
decreased startle reflex 2 | 48
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
hemorrhage 2 | 12
increased circulating chloride... 2 | 43
increased fasted circulating g... 2 | 68
increased lean body mass 2 | 107
persistence of hyaloid vascula... 2 | 22
prenatal lethality prior to he... 2 | 64
abnormal bone mineralization 1 | 55
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal facial morphology 1 | 9
abnormal glucose homeostasis 1 | 5
abnormal head shape 1 | 4
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal locomotor activation 1 | 26
abnormal motor coordination/ b... 1 | 4
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal skin coloration 1 | 18
abnormal vocalization 1 | 21
absent heartbeat 1 | 6
absent startle reflex 1 | 15
anophthalmia 1 | 20
corneal opacity 1 | 25
cyanosis 1 | 6
decreased Ly6C low monocyte nu... 1 | 23
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased mean corpuscular vol... 1 | 50
decreased red blood cell distr... 1 | 11
decreased vertical activity 1 | 22
edema 1 | 11
fused cornea and lens 1 | 4
fused phalanges 1 | 1
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased CD8-positive, alpha-... 1 | 11
increased Ly6C high monocyte n... 1 | 12
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
male infertility 1 | 62
pale liver 1 | 5
pale yolk sac 1 | 12
pallor 1 | 13
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

osteosarcoma 60 | 7,933
Carcinoma 59 | 2,147
ovarian cancer 59 | 8,484
psoriasis 52 | 6,685
glioblastoma 47 | 5,572
medulloblastoma, large-cell 46 | 6,234
atypical teratoid / rhabdoid tumor 39 | 4,369
lung cancer 38 | 4,466
malignant mesothelioma 37 | 3,162
pediatric high grade glioma 31 | 2,712
primitive neuroectodermal tumor 30 | 3,031
Breast cancer 29 | 3,094
non-small cell lung cancer 29 | 2,798
lung carcinoma 28 | 2,844
pilocytic astrocytoma 28 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,988
posterior fossa group B ependymoma 26 | 1,530
invasive ductal carcinoma 25 | 2,950
lung adenocarcinoma 24 | 2,713
nasopharyngeal carcinoma 22 | 1,056
ductal carcinoma in situ 21 | 1,745
group 3 medulloblastoma 21 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
oligodendroglioma 20 | 2,849
ependymoma 17 | 2,514
adrenocortical carcinoma 16 | 1,427
pituitary cancer 16 | 1,972
subependymal giant cell astrocytoma 16 | 2,287
colon cancer 15 | 1,475
sonic hedgehog group medulloblastoma 15 | 1,482
acute quadriplegic myopathy 14 | 1,157
adult high grade glioma 14 | 2,148
chronic rhinosinusitis 14 | 512
ulcerative colitis 14 | 2,087
breast carcinoma 13 | 1,614
interstitial cystitis 13 | 2,299
pancreatic cancer 13 | 2,300
Atopic dermatitis 12 | 944
Pick disease 12 | 1,893
astrocytoma 12 | 1,493
Endometriosis 11 | 535
astrocytic glioma 11 | 2,241
diabetes mellitus 11 | 1,663
IGA Glomerulonephritis 10 | 454
Primary ciliary dyskinesia 10 | 73
Situs Inversus 10 | 48
group 4 medulloblastoma 10 | 1,875
posterior fossa group A ependymoma 10 | 1,511
Sensorineural hearing loss 9 | 107
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Hypertrophic Cardiomyopathy 8 | 56
Neuropathy 8 | 210
Nonsyndromic deafness 8 | 121
cutaneous lupus erythematosus 8 | 1,056
cystic fibrosis 8 | 1,665
juvenile dermatomyositis 8 | 1,189
Amyotrophic Lateral Sclerosis 7 | 431
Cardiomyopathy 7 | 110
Neurodegenerative disease 7 | 383
Paraplegia 7 | 71
atypical teratoid/rhabdoid tumor 7 | 1,095
fibroadenoma 7 | 557
medulloblastoma 7 | 1,524
progressive supranuclear palsy 7 | 674
spina bifida 7 | 1,064
Cancer 6 | 2,346
Cardiovascular system disease 6 | 194
Duchenne muscular dystrophy 6 | 602
Kartagener Syndrome 6 | 32
Kidney cancer 6 | 118
non-small cell lung carcinoma 6 | 413
primary pancreatic ductal adenocarcinoma 6 | 1,271
Becker muscular dystrophy 5 | 187
Distal arthrogryposis 5 | 45
Male infertility 5 | 170
Microcephaly 5 | 149
Multiple myeloma 5 | 1,327
Myopathy 5 | 128
acute myeloid leukemia 5 | 780
Alzheimer's disease 4 | 644
Cardiomyopathy, Hypertrophic, Familial 4 | 21
Dilated cardiomyopathy 4 | 50
Left ventricular noncompaction 4 | 23
Ophthalmoplegia 4 | 18
Peripheral Neuropathy 4 | 303
Polydactyly 4 | 93
Vascular disease 4 | 281
Weight Gain 4 | 87
cystic fibrosis and chronic rhinosinusitis 4 | 213
dermatomyositis 4 | 933
facioscapulohumeral dystrophy 4 | 286
gastric carcinoma 4 | 832
tuberculosis 4 | 1,557
tuberculosis and treatment for 6 months 4 | 686
Attention deficit hyperactivity disorder 3 | 156
Down syndrome 3 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
hepatocellular carcinoma 3 | 532
non diabetic and post-ischemic heart failure 3 | 200

Tissue

Blood and immune system 132 | 17,995
Cardiovascular System 132 | 17,958
Female tissues 132 | 18,647
Liver and Pancreas 132 | 18,136
Male tissues 132 | 17,969
Nervous System 132 | 18,561
Digestive Tract 131 | 18,473
Endocrine System 131 | 18,512
Skin and soft tissues 131 | 18,115
Urinary Tract 131 | 18,444
Respiratory system 130 | 17,484

Target Family

Non-IDG 130 | 11,971
Kinase 2 | 634
Transporter 1 | 473

UniProt Keyword

Motor protein 133 | 133
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Myosin light chain 6B MYL6B Tdark Non-IDG -0.43175 2.57 113
Dynein light chain Tctex-type 1 DYNLT1 Tbio Non-IDG -2.32941 210.3 40
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Kinesin-like protein KIFC3 KIFC3 Tchem Non-IDG -1.08696 12.5 48
Dynein heavy chain 14, axonemal DNAH14 Tdark Non-IDG -0.16914 1.36 38
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.33400 20.0 84
Tctex1 domain-containing protein 3 TCTE3 Tdark Non-IDG -0.56557 4.53 21
Myosin-3 MYH3 Tbio Non-IDG -1.66510 45.6 38
Kinesin-like protein KIF18A KIF18A Tbio Non-IDG -1.37782 29.6 81