Development Level

Tbio 34 | 10,625
Tchem 27 | 1,890
Tclin 14 | 602
Tdark 6 | 7,003

IMPC Term

decreased total body fat amoun... 3 | 186
abnormal bone structure 2 | 131
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 195
decreased mean platelet volume 2 | 12
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
increased lean body mass 2 | 107
small kidney 2 | 10
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal clavicle morphology 1 | 5
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 28
abnormal scapula morphology 1 | 3
abnormal tail bud morphology 1 | 6
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
abnormal vitreous body morphol... 1 | 7
absent mammary gland 1 | 1
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased skeletal muscle mass 1 | 1
decreased vertical activity 1 | 22
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased respiratory quotient 1 | 12
increased total body fat amoun... 1 | 57
persistence of hyaloid vascula... 1 | 22
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
shortened QRS complex duration 1 | 1
small heart 1 | 8
small ovary 1 | 1
small spleen 1 | 11
small uterus 1 | 1
thin skin 1 | 1

Disease

psoriasis 39 | 6,685
osteosarcoma 26 | 7,933
lung cancer 24 | 4,466
medulloblastoma, large-cell 24 | 6,234
lung carcinoma 22 | 2,844
ovarian cancer 21 | 8,484
glioblastoma 20 | 5,572
interstitial cystitis 20 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
non-small cell lung cancer 19 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
Cancer 18 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
adrenocortical carcinoma 16 | 1,427
atypical teratoid / rhabdoid tumor 16 | 4,369
pilocytic astrocytoma 16 | 3,086
oligodendroglioma 14 | 2,849
Prostatic Neoplasms 13 | 471
lung adenocarcinoma 13 | 2,713
malignant mesothelioma 13 | 3,162
Breast cancer 12 | 3,094
cutaneous lupus erythematosus 12 | 1,056
Hypertension 11 | 287
ductal carcinoma in situ 11 | 1,745
posterior fossa group A ependymoma 11 | 1,511
primitive neuroectodermal tumor 11 | 3,031
tuberculosis 11 | 1,557
adult high grade glioma 10 | 2,148
cystic fibrosis 10 | 1,665
pediatric high grade glioma 10 | 2,712
ulcerative colitis 10 | 2,087
Liver disease 9 | 219
Pick disease 9 | 1,893
group 3 medulloblastoma 9 | 2,254
invasive ductal carcinoma 9 | 2,950
pancreatic cancer 9 | 2,300
pituitary cancer 9 | 1,972
Peripheral Neuropathy 8 | 303
Schizophrenia 8 | 501
active Crohn's disease 8 | 918
astrocytic glioma 8 | 2,241
chronic rhinosinusitis 8 | 512
ependymoma 8 | 2,514
group 4 medulloblastoma 8 | 1,875
Congenital adrenal hyperplasia 7 | 74
adrenocortical adenoma 7 | 134
aldosterone-producing adenoma 7 | 664
breast carcinoma 7 | 1,614
diabetes mellitus 7 | 1,663
medulloblastoma 7 | 1,524
nephrosclerosis 7 | 329
Adenocarcinoma 6 | 115
Drug-Induced Liver Injury 6 | 118
Lung Neoplasms 6 | 171
Mammary Neoplasms 6 | 410
Obesity 6 | 616
primary pancreatic ductal adenocarcinoma 6 | 1,271
Adenoma 5 | 165
Atopic dermatitis 5 | 944
Cholestasis 5 | 93
Endometriosis 5 | 535
astrocytoma 5 | 1,493
gastric carcinoma 5 | 832
nasopharyngeal carcinoma 5 | 1,056
subependymal giant cell astrocytoma 5 | 2,287
Adrenal cortical adenoma 4 | 10
Adverse reaction to drug 4 | 54
Alzheimer's disease 4 | 644
Antley-Bixler syndrome 4 | 15
Attention deficit hyperactivity disorder 4 | 156
Candidiasis of mouth 4 | 5
Candidiasis of skin 4 | 6
Cushing's syndrome 4 | 47
Human immunodeficiency virus infection 4 | 6
Hyperandrogenism 4 | 32
Liver carcinoma 4 | 217
Major Depressive Disorder 4 | 106
Parkinson's disease 4 | 364
Pityriasis versicolor 4 | 18
Polycystic Ovary Syndrome 4 | 332
Tinea corporis 4 | 25
Tinea cruris 4 | 12
Tinea pedis 4 | 30
esophageal adenocarcinoma 4 | 737
head and neck cancer and chronic obstructive pulmonary disease 4 | 237
mucosa-associated lymphoid tissue lymphoma 4 | 480
non diabetic and post-ischemic heart failure 4 | 200
non primary Sjogren syndrome sicca 4 | 840
posterior fossa group B ependymoma 4 | 1,530
sonic hedgehog group medulloblastoma 4 | 1,482
substance-related disorder 4 | 105
Atrial Fibrillation 3 | 110
Male infertility 3 | 170
Multiple Sclerosis 3 | 498
Prostate cancer 3 | 172
fibroadenoma 3 | 557
head and neck cancer 3 | 270
inflammatory breast cancer 3 | 404
spina bifida 3 | 1,064

Tissue

Digestive Tract 79 | 18,473
Endocrine System 79 | 18,512
Female tissues 79 | 18,647
Nervous System 79 | 18,561
Skin and soft tissues 79 | 18,115
Urinary Tract 79 | 18,444
Blood and immune system 78 | 17,995
Cardiovascular System 78 | 17,958
Liver and Pancreas 78 | 18,136
Male tissues 76 | 17,969
Respiratory system 76 | 17,484

Target Family

Enzyme 49 | 4,146
Non-IDG 32 | 11,971

UniProt Keyword

Monooxygenase 81 | 81
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dimethylaniline monooxygenase [N-oxide-forming] 5 FMO5 Tbio Enzyme -0.93021 9.11 128
24-hydroxycholesterol 7-alpha-hydroxylase CYP39A1 Tbio Enzyme -0.95411 6.43 97
Cytochrome P450 4V2 CYP4V2 Tbio Non-IDG -2.66290 481.8 87
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -1.98060 100.6 25
Thromboxane-A synthase TBXAS1 Tchem Enzyme -3.06668 1228.9 241
Protein-methionine sulfoxide oxidase MICAL3 MICAL3 Tdark Enzyme -0.70899 4.79 16
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.65191 464.3 66
Tryptophan 5-hydroxylase 2 TPH2 Tchem Enzyme -2.40600 295.6 323
Cytochrome P450 4B1 CYP4B1 Tbio Non-IDG -1.77340 65.4 88
Cytochrome P450 11B1, mitochondrial CYP11B1 Tclin Enzyme -2.62509 411.6 105