Development Level

Tbio 7 | 11,651

IMPC Phenotype

decreased body length 2 | 101
preweaning lethality, complete... 2 | 979

Disease

Carcinoma 4 | 11,493
Molybdenum Cofactor Deficiency, Complementation Group A 4 | 4
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
Combined molybdoflavoprotein enzyme deficiency 3 | 3
Xanthinuria 3 | 10
ductal carcinoma in situ 3 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Axonal loss 2 | 7
Big calvaria 2 | 147
Cerebral atrophy 2 | 178
Chubby cheeks 2 | 50
Degenerative brain disorder 2 | 100
Dilated ventricles (finding) 2 | 121
Ectopia Lentis 2 | 17
Encephalomalacia 2 | 3
Epilepsy 2 | 792
Feeding difficulties 2 | 127
Frontal bossing 2 | 157
Full cheeks 2 | 50
Gliosis 2 | 56
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hyperplasia of cheeks 2 | 50
Hypertrophy of cheeks 2 | 50
Hypoplasia of corpus callosum 2 | 90
Hypouricemia 2 | 5
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Increased urinary hypoxanthine 2 | 2
Increased urinary taurine 2 | 2
Intellectual disability 2 | 1,016
Long face 2 | 71
Long philtrum 2 | 137
Molybdenum Cofactor Deficiency, Complementation Group B 2 | 2
Myoclonic spasms 2 | 2
Nystagmus 2 | 317
Opisthotonus 2 | 14
Orbital separation excessive 2 | 244
Peripheral demyelination 2 | 16
Pick disease 2 | 1,894
Poor growth 2 | 114
Progressive disorder 2 | 142
Puffy cheeks 2 | 50
Seizures 2 | 596
Short nose 2 | 132
Small head 2 | 374
Small nose 2 | 132
Spastic Quadriplegia 2 | 42
Supratentorial atrophy 2 | 94
Thick vermilion border 2 | 25
Very poor growth 2 | 114
Xanthine stones 2 | 3
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
Alcoholic Intoxication, Chronic 1 | 289
Alcoholism 1 | 45
Alzheimer's disease 1 | 658
Autism spectrum disorder 1 | 101
Axial hypotonia 1 | 46
CHARGE syndrome 1 | 26
Choanal Atresia 1 | 42
Cocaine-Related Disorders 1 | 92
Duane-radial ray syndrome 1 | 8
Exaggerated acoustic startle response 1 | 8
Exaggerated startle response 1 | 8
Friedreich ataxia 1 | 24
Hernia, Inguinal 1 | 89
Hyperexplexia 1 | 8
Hyperreflexia 1 | 209
Hypokinesia 1 | 19
Infantile onset 1 | 238
Muscle Hypertonia 1 | 88
Myoclonus 1 | 74
Polymicrogyria 1 | 48
Poor eye contact 1 | 12
Poor head control 1 | 14
Pulmonary aspiration 1 | 8
Spontaneous abortion 1 | 113
Stiff-Person syndrome 1 | 12
Tonic - clonic seizures 1 | 44
Umbilical hernia 1 | 93
adrenocortical carcinoma 1 | 1,428
cystic fibrosis 1 | 1,696
hereditary spastic paraplegia 1 | 318
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
sarcoidosis 1 | 370
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 2 | 12,091

UniProt Keyword

Molybdenum cofactor biosynthes... 7 | 7
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cysteine desulfurase, mitochondrial NFS1 Tbio Enzyme -1.70267 46.3 131
Molybdopterin synthase sulfur carrier subunit MOCS2 Tbio Enzyme -2.05483 207.6 92
Molybdenum cofactor sulfurase MOCOS Tbio Enzyme -1.10485 13.1 28
Molybdopterin synthase catalytic subunit MOCS2 Tbio Enzyme -2.05483 207.6 92
Molybdenum cofactor biosynthesis protein 1 MOCS1 Tbio Non-IDG -1.28570 20.9 138
Gephyrin GPHN Tbio Non-IDG -2.56617 383.9 235
Adenylyltransferase and sulfurtransferase MOCS3 MOCS3 Tbio Enzyme -1.08678 10.9 128