Development Level

Tbio 220 | 11,445
Tchem 32 | 1,598
Tdark 20 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 4 | 37
Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, complete... 38 | 979
preweaning lethality, incomple... 13 | 499
embryonic lethality prior to o... 12 | 239
embryonic lethality prior to t... 11 | 278
abnormal embryo size 7 | 220
embryonic growth retardation 6 | 106
abnormal seminal vesicle morph... 5 | 114
increased circulating HDL chol... 5 | 80
cataract 4 | 92
decreased body weight 4 | 161
increased circulating alkaline... 4 | 122
increased mean corpuscular vol... 4 | 92
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
abnormal placenta size 3 | 20
decreased caudal vertebrae num... 3 | 53
decreased mean corpuscular hem... 3 | 50
decreased mean corpuscular vol... 3 | 79
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 96
male infertility 3 | 123
small testis 3 | 58
thrombocytopenia 3 | 56
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal craniofacial morpholo... 2 | 33
abnormal kidney morphology 2 | 65
abnormal placenta morphology 2 | 5
abnormal skin coloration 2 | 25
abnormal snout morphology 2 | 23
abnormal tail morphology 2 | 25
abnormal testis morphology 2 | 43
anophthalmia 2 | 33
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased red blood cell distr... 2 | 41
decreased total body fat amoun... 2 | 207
edema 2 | 59
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
impaired glucose tolerance 2 | 75
increased circulating chloride... 2 | 41
increased circulating creatini... 2 | 38
increased leukocyte cell numbe... 2 | 47
increased mean platelet volume 2 | 45
microphthalmia 2 | 26
prenatal lethality 2 | 28
prenatal lethality prior to he... 2 | 87
syndactyly 2 | 23
thrombocytosis 2 | 27
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal pancreas morphology 1 | 13
abnormal posture 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
brachydactyly 1 | 19
corneal opacity 1 | 32
decreased IgG1 level 1 | 8
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased fluid intake 1 | 3
decreased lean body mass 1 | 135
enlarged epididymis 1 | 31
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased total body fat amoun... 1 | 134
long tibia 1 | 25
small kidney 1 | 16
small spleen 1 | 19
tremors 1 | 39
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

ovarian cancer 182 | 8,520
Carcinoma 177 | 11,493
medulloblastoma, large-cell 151 | 6,241
glioblastoma 138 | 5,792
osteosarcoma 136 | 7,950
group 3 medulloblastoma 133 | 4,104
psoriasis 129 | 6,694
atypical teratoid / rhabdoid tumor 128 | 5,112
Breast cancer 117 | 3,578
primitive neuroectodermal tumor 112 | 3,035
lung cancer 111 | 4,740
ependymoma 94 | 4,679
non-small cell lung cancer 94 | 2,890
adult high grade glioma 93 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 89 | 2,989
adrenocortical carcinoma 85 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 84 | 3,291
malignant mesothelioma 84 | 3,232
invasive ductal carcinoma 78 | 2,951
lung adenocarcinoma 73 | 2,716
Cancer 66 | 2,499
ductal carcinoma in situ 57 | 1,745
Atopic dermatitis 53 | 952
breast carcinoma 53 | 1,638
pancreatic cancer 53 | 2,398
oligodendroglioma 51 | 2,850
Kidney cancer 50 | 2,613
colon cancer 49 | 1,478
Endometriosis 48 | 540
nasopharyngeal carcinoma 48 | 1,058
Astrocytoma, Pilocytic 47 | 3,081
Multiple myeloma 34 | 1,332
Pick disease 33 | 1,894
astrocytic glioma 31 | 2,597
ulcerative colitis 29 | 1,819
Waldenstrons macroglobulinemia 28 | 765
pituitary cancer 28 | 1,972
Intellectual disability 27 | 1,016
astrocytoma 27 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
subependymal giant cell astrocytoma 26 | 2,287
tuberculosis 26 | 2,010
interstitial cystitis 25 | 2,312
pediatric high grade glioma 24 | 1,064
group 4 medulloblastoma 22 | 1,855
Cognitive delay 21 | 608
Global developmental delay 21 | 608
Mental and motor retardation 21 | 608
acute quadriplegic myopathy 20 | 1,158
dermatomyositis 20 | 966
Small head 19 | 374
Short stature 18 | 531
lung carcinoma 18 | 2,843
primary Sjogren syndrome 18 | 735
Autosomal recessive predisposition 17 | 1,442
diabetes mellitus 17 | 1,728
juvenile dermatomyositis 17 | 1,187
Dull intelligence 16 | 645
Hypoplastic mandible condyle 16 | 275
Low intelligence 16 | 645
Mandibular hypoplasia 16 | 275
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Microcephaly 16 | 166
Micrognathism 16 | 275
Poor school performance 16 | 645
Rheumatoid arthritis 16 | 1,191
non primary Sjogren syndrome sicca 15 | 891
primary pancreatic ductal adenocarcinoma 15 | 1,109
progressive supranuclear palsy 15 | 676
active Crohn's disease 14 | 922
esophageal adenocarcinoma 14 | 737
posterior fossa group A ependymoma 14 | 468
acute myeloid leukemia 13 | 783
medulloblastoma 12 | 720
Liver Cirrhosis, Experimental 11 | 769
Alzheimer's disease 10 | 658
Fetal Growth Retardation 10 | 189
Infant, Small for Gestational Age 10 | 176
Intrauterine retardation 10 | 176
Polycystic ovary syndrome 10 | 360
Schizophrenia 10 | 1,160
spina bifida 10 | 1,074
Acquired metabolic disease 9 | 336
Amyotrophic lateral sclerosis 9 | 451
Liver cancer 9 | 604
Melanoma 9 | 711
Type 2 diabetes mellitus 9 | 272
chronic rhinosinusitis 9 | 512
cystic fibrosis 9 | 1,696
gastric carcinoma 9 | 807
pancreatic carcinoma 9 | 562
Cerebellar Hypoplasia 8 | 61
Cryptorchidism 8 | 296
Dilated ventricles (finding) 8 | 121
Down syndrome 8 | 499
Glaucoma 8 | 239
gastric cancer 8 | 459
tuberculosis and treatment for 6 months 8 | 409

Tissue

Endocrine System 271 | 18,159
Male tissues 269 | 17,142
Digestive Tract 268 | 17,369
Female tissues 268 | 17,400
Nervous System 268 | 16,725
Respiratory system 268 | 16,393
Skin and soft tissues 268 | 17,230
Blood and immune system 267 | 16,909
Liver and Pancreas 267 | 16,750
Urinary Tract 267 | 16,678
Cardiovascular System 260 | 15,192

Target Family

Non-IDG 198 | 12,091
Enzyme 40 | 4,145
Kinase 27 | 634
Epigenetic 3 | 242
Transcription Factor 3 | 1,400
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Mitosis 273 | 273
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein timeless homolog TIMELESS Tbio Non-IDG -2.76871 578.0 138
Kinesin-like protein KIF11 KIF11 Tchem Non-IDG -2.61375 404.4 300
BUB3-interacting and GLEBS motif-containing protein ZNF207 ZNF207 Tbio Non-IDG -0.82146 6.93 264
Spindle and kinetochore-associated protein 2 SKA2 Tbio Non-IDG -1.23206 10.2 108
Integrator complex subunit 13 INTS13 Tdark Non-IDG -1.21861 15.4 36
Anaphase-promoting complex subunit 4 ANAPC4 Tbio Enzyme 0.43 0.13 156
Anaphase-promoting complex subunit 7 ANAPC7 Tbio Enzyme -0.17118 1.40 73
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
RNA polymerase II subunit A C-terminal domain phosphatase CTDP1 Tbio Enzyme -1.88697 80.7 113
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166