Development Level

Tbio 193 | 10,625
Tchem 38 | 1,890
Tdark 30 | 7,003
Tclin 1 | 602

Collection

Eligible Kinase Proteins 4 | 134

IMPC Term

preweaning lethality, complete... 27 | 633
embryonic lethality prior to t... 8 | 187
embryonic lethality prior to o... 7 | 148
decreased body weight 5 | 174
embryonic growth retardation 5 | 28
abnormal embryo size 4 | 112
preweaning lethality, incomple... 4 | 260
abnormal coat/hair pigmentatio... 3 | 54
abnormal gait 3 | 51
decreased circulating serum al... 3 | 79
decreased lean body mass 3 | 195
increased bone mineral density 3 | 52
increased circulating HDL chol... 3 | 63
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 68
increased mean corpuscular vol... 3 | 91
thrombocytopenia 3 | 46
abnormal craniofacial morpholo... 2 | 12
abnormal cranium morphology 2 | 32
abnormal placenta morphology 2 | 4
abnormal placenta size 2 | 10
abnormal seminal vesicle morph... 2 | 47
abnormal snout morphology 2 | 18
anophthalmia 2 | 20
decreased bone mineral content 2 | 157
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased erythrocyte cell num... 2 | 43
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
decreased total body fat amoun... 2 | 186
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased circulating choleste... 2 | 53
increased exploration in new e... 2 | 56
increased grip strength 2 | 83
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
increased or absent threshold ... 2 | 128
prenatal lethality 2 | 16
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal brain morphology 1 | 6
abnormal cornea morphology 1 | 24
abnormal head shape 1 | 4
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 11
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 100
abnormal skin coloration 1 | 18
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
decreased CD8-positive, alpha-... 1 | 26
decreased IgG1 level 1 | 4
decreased basophil cell number 1 | 11
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased hematocrit 1 | 25
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
edema 1 | 11
enlarged lymph nodes 1 | 27
hydroencephaly 1 | 6
hypoactivity 1 | 89
increased B cell number 1 | 23
increased CD4-positive, CD25-p... 1 | 18
increased alpha-beta T cell nu... 1 | 9
increased body length 1 | 20
increased circulating alanine ... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating total pr... 1 | 20
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased red blood cell distr... 1 | 21
microphthalmia 1 | 15
narrow eye opening 1 | 15
pallor 1 | 13
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small testis 1 | 37
straub tail 1 | 26
thrombocytosis 1 | 23
urinary bladder obstruction 1 | 2
vertebral fusion 1 | 23

Disease

ovarian cancer 174 | 8,492
medulloblastoma, large-cell 145 | 6,234
glioblastoma 131 | 5,572
osteosarcoma 127 | 7,933
psoriasis 126 | 6,685
primitive neuroectodermal tumor 109 | 3,031
lung cancer 102 | 4,473
Breast cancer 98 | 3,099
atypical teratoid / rhabdoid tumor 93 | 4,369
pediatric high grade glioma 91 | 2,712
non-small cell lung cancer 89 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 86 | 2,988
adrenocortical carcinoma 83 | 1,427
malignant mesothelioma 83 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,289
group 3 medulloblastoma 79 | 2,254
invasive ductal carcinoma 74 | 2,950
lung adenocarcinoma 70 | 2,714
Cancer 63 | 2,346
ductal carcinoma in situ 55 | 1,745
posterior fossa group A ependymoma 53 | 1,511
Atopic dermatitis 51 | 944
pancreatic cancer 51 | 2,300
breast carcinoma 50 | 1,614
oligodendroglioma 49 | 2,849
Endometriosis 48 | 535
colon cancer 48 | 1,475
nasopharyngeal carcinoma 48 | 1,056
pilocytic astrocytoma 44 | 3,086
sonic hedgehog group medulloblastoma 41 | 1,482
Carcinoma 36 | 2,147
ependymoma 36 | 2,514
atypical teratoid/rhabdoid tumor 35 | 1,095
Multiple myeloma 33 | 1,328
Pick disease 31 | 1,893
IGA Glomerulonephritis 30 | 454
ulcerative colitis 29 | 2,087
astrocytic glioma 28 | 2,241
astrocytoma 27 | 1,493
Waldenstrons macroglobulinemia 26 | 765
pituitary cancer 26 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
subependymal giant cell astrocytoma 25 | 2,287
medulloblastoma 24 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
adult high grade glioma 23 | 2,148
interstitial cystitis 23 | 2,299
posterior fossa group B ependymoma 21 | 1,530
tuberculosis 21 | 1,563
inflammatory breast cancer 20 | 404
dermatomyositis 19 | 967
group 4 medulloblastoma 19 | 1,875
acute quadriplegic myopathy 18 | 1,157
primary Sjogren syndrome 18 | 789
Rheumatoid Arthritis 17 | 1,171
lung carcinoma 16 | 2,844
Microcephaly 15 | 149
non primary Sjogren syndrome sicca 15 | 840
primary pancreatic ductal adenocarcinoma 15 | 1,271
Intellectual disability 14 | 573
diabetes mellitus 14 | 1,663
progressive supranuclear palsy 14 | 674
active Crohn's disease 13 | 918
juvenile dermatomyositis 13 | 1,189
esophageal adenocarcinoma 12 | 737
acute myeloid leukemia 11 | 785
Polycystic Ovary Syndrome 10 | 335
pancreatic carcinoma 10 | 567
Alzheimer's disease 9 | 644
chronic rhinosinusitis 9 | 512
Acquired metabolic disease 8 | 267
Down syndrome 8 | 548
Peripheral Neuropathy 8 | 303
Type 2 diabetes mellitus 8 | 192
cystic fibrosis and chronic rhinosinusitis 8 | 213
gastric carcinoma 8 | 832
spina bifida 8 | 1,064
tuberculosis and treatment for 6 months 8 | 686
Cornelia de Lange syndrome 7 | 21
Roberts syndrome 7 | 16
cutaneous lupus erythematosus 7 | 1,056
gastric cancer 7 | 436
Amyotrophic Lateral Sclerosis 6 | 432
Bipolar Disorder 6 | 266
Lissencephaly 6 | 61
Schizophrenia 6 | 503
cystic fibrosis 6 | 1,670
non-small cell lung carcinoma 6 | 413
Gaucher disease type 1 5 | 171
Mammary Neoplasms 5 | 410
Melanoma 5 | 261
Stomach Neoplasms 5 | 282
aldosterone-producing adenoma 5 | 664
hereditary spastic paraplegia 5 | 313
tuberculosis and treatment for 3 months 5 | 327
Prostate cancer 4 | 172
Prostatic Neoplasms 4 | 471
hepatocellular carcinoma 4 | 550
mucosa-associated lymphoid tissue lymphoma 4 | 480
periodontitis 4 | 269

Tissue

Blood and immune system 260 | 17,995
Cardiovascular System 260 | 17,958
Digestive Tract 260 | 18,473
Endocrine System 260 | 18,512
Female tissues 260 | 18,647
Liver and Pancreas 260 | 18,136
Male tissues 260 | 17,969
Nervous System 260 | 18,561
Skin and soft tissues 260 | 18,115
Urinary Tract 260 | 18,444
Respiratory system 259 | 17,484

Target Family

Non-IDG 187 | 11,969
Enzyme 40 | 4,146
Kinase 27 | 634
Epigenetic 3 | 242
Transcription Factor 3 | 1,400
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Mitosis 262 | 262
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.24054 16.5 27
Protein asunder homolog ASUN Tdark Non-IDG -1.14746 14.4 31
Cell division control protein 6 homolog CDC6 Tchem Non-IDG -2.49821 321.6 473
Ankyrin repeat domain-containing protein 53 ANKRD53 Tbio Non-IDG 0.30 0.62 79
Anaphase-promoting complex subunit 13 ANAPC13 Tbio Enzyme -0.70781 4.87 42
Cohesin subunit SA-1 STAG1 Tbio Non-IDG -2.44719 274.6 177
Protein FAM64A FAM64A Tdark Non-IDG -1.19498 15.5 44
Sorting nexin-33 SNX33 Tbio Non-IDG -0.45756 4.34 87
Serine/threonine-protein kinase Nek6 NEK6 Tchem Kinase -1.52648 33.8 170
Cell division cycle-associated protein 3 CDCA3 Tbio Non-IDG -0.68059 8.68 125