Development Level

Tbio 79 | 10,625
Tchem 19 | 1,890
Tdark 9 | 7,003
Tclin 5 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased body weight 6 | 174
decreased heart weight 3 | 44
decreased lean body mass 3 | 195
hypoactivity 3 | 89
abnormal behavior 2 | 226
decreased circulating glucose ... 2 | 121
decreased circulating triglyce... 2 | 83
increased heart weight 2 | 37
increased mean corpuscular hem... 2 | 93
preweaning lethality, incomple... 2 | 260
thrombocytopenia 2 | 46
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal glucose homeostasis 1 | 5
abnormal locomotor activation 1 | 26
abnormal tibia morphology 1 | 14
absent vibrissae 1 | 14
corneal opacity 1 | 25
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
enlarged heart 1 | 111
female infertility 1 | 34
hydrometra 1 | 13
hyperactivity 1 | 108
increased bone mineral content 1 | 92
increased circulating LDL chol... 1 | 15
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating lipase l... 1 | 1
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
macrophthalmia 1 | 2
persistence of hyaloid vascula... 1 | 22
preweaning lethality, complete... 1 | 633
short tibia 1 | 82

Disease

ovarian cancer 64 | 8,484
osteosarcoma 51 | 7,933
medulloblastoma, large-cell 48 | 6,234
lung cancer 41 | 4,466
glioblastoma 38 | 5,572
atypical teratoid / rhabdoid tumor 35 | 4,369
psoriasis 33 | 6,685
invasive ductal carcinoma 25 | 2,950
Breast cancer 20 | 3,094
Pick disease 20 | 1,893
ependymoma 19 | 2,514
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
ulcerative colitis 19 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
malignant mesothelioma 18 | 3,162
non-small cell lung cancer 18 | 2,798
Multiple myeloma 17 | 1,327
lung adenocarcinoma 17 | 2,713
primitive neuroectodermal tumor 17 | 3,031
adult high grade glioma 16 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
lung carcinoma 16 | 2,844
oligodendroglioma 16 | 2,849
pilocytic astrocytoma 16 | 3,086
Alzheimer's disease 15 | 644
astrocytic glioma 15 | 2,241
ductal carcinoma in situ 15 | 1,745
pancreatic cancer 15 | 2,300
diabetes mellitus 14 | 1,663
pediatric high grade glioma 14 | 2,712
pituitary cancer 14 | 1,972
sonic hedgehog group medulloblastoma 14 | 1,482
Cancer 13 | 2,346
group 4 medulloblastoma 13 | 1,875
Neurodegenerative disease 12 | 383
acute quadriplegic myopathy 12 | 1,157
breast carcinoma 12 | 1,614
colon cancer 12 | 1,475
dermatomyositis 12 | 933
interstitial cystitis 12 | 2,299
tuberculosis 11 | 1,557
Obesity 10 | 616
Parkinson's disease 10 | 364
tuberculosis and treatment for 6 months 10 | 686
Rheumatoid Arthritis 9 | 1,160
astrocytoma 9 | 1,493
cystic fibrosis 9 | 1,665
group 3 medulloblastoma 9 | 2,254
juvenile dermatomyositis 9 | 1,189
medulloblastoma 9 | 1,524
posterior fossa group B ependymoma 9 | 1,530
Optic atrophy 8 | 43
atypical teratoid/rhabdoid tumor 8 | 1,095
esophageal adenocarcinoma 8 | 737
progressive supranuclear palsy 8 | 674
subependymal giant cell astrocytoma 8 | 2,287
Diabetes Mellitus, Experimental 7 | 106
active Crohn's disease 7 | 918
aldosterone-producing adenoma 7 | 664
posterior fossa group A ependymoma 7 | 1,511
primary pancreatic ductal adenocarcinoma 7 | 1,271
Carcinoma 6 | 2,147
Myocardial Ischemia 6 | 169
Waldenstrons macroglobulinemia 6 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
hereditary spastic paraplegia 6 | 313
Amyotrophic Lateral Sclerosis 5 | 431
Charcot-Marie-Tooth disease 5 | 74
IGA Glomerulonephritis 5 | 454
Neuropathy 5 | 210
Prostatic Neoplasms 5 | 471
Toxic encephalopathy 5 | 131
Vascular disease 5 | 281
non primary Sjogren syndrome sicca 5 | 840
primary Sjogren syndrome 5 | 789
Atopic dermatitis 4 | 944
Autistic Disorder 4 | 320
COPD 4 | 113
Dementia 4 | 129
Diabetes Mellitus, Non-Insulin-Dependent 4 | 157
Duchenne muscular dystrophy 4 | 602
Endometriosis 4 | 535
Intellectual disability 4 | 573
Mammary Neoplasms 4 | 410
Parkinson Disease 4 | 102
Polycystic Ovary Syndrome 4 | 332
Schizophrenia 4 | 501
acute myeloid leukemia 4 | 780
adrenocortical carcinoma 4 | 1,427
gastric cancer 4 | 430
gastric carcinoma 4 | 832
nasopharyngeal carcinoma 4 | 1,056
pancreatic carcinoma 4 | 567
sarcoidosis 4 | 358
spina bifida 4 | 1,064
Attention deficit hyperactivity disorder 3 | 156
cutaneous lupus erythematosus 3 | 1,056
mucosa-associated lymphoid tissue lymphoma 3 | 480
nephrosclerosis 3 | 329

Tissue

Cardiovascular System 111 | 17,958
Female tissues 111 | 18,647
Male tissues 111 | 17,969
Nervous System 111 | 18,561
Blood and immune system 110 | 17,995
Digestive Tract 110 | 18,473
Endocrine System 110 | 18,512
Liver and Pancreas 110 | 18,136
Urinary Tract 110 | 18,444
Respiratory system 109 | 17,484
Skin and soft tissues 109 | 18,115

Target Family

Non-IDG 59 | 11,971
Enzyme 32 | 4,146
Kinase 11 | 634
Transporter 5 | 473
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Nuclear Receptor 1 | 48

UniProt Keyword

Mitochondrion outer membrane 112 | 112
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitofusin-1 MFN1 Tbio Non-IDG -1.99234 91.2 0
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.30451 203.2 252
NADH-cytochrome b5 reductase 3 CYB5R3 Tchem Enzyme -1.93440 89.2 241
Glycerol-3-phosphate acyltransferase 2, mitochondrial GPAT2 Tdark Enzyme -0.79239 6.58 36
CDGSH iron-sulfur domain-containing protein 1 CISD1 Tchem Non-IDG -1.66527 54.6 80
Protein misato homolog 1 MSTO1 Tdark Non-IDG -1.74451 53.5 48
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.95326 94.6 135
Long-chain-fatty-acid--CoA ligase 6 ACSL6 Tbio Enzyme -1.83623 72.3 120
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.50852 352.2 235
FUN14 domain-containing protein 1 FUNDC1 Tbio Non-IDG -0.77521 8.18 110