Development Level

Tbio 182 | 10,625
Tdark 55 | 7,003
Tchem 33 | 1,890
Tclin 9 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 16 | 633
abnormal behavior 7 | 226
decreased body weight 5 | 174
decreased bone mineral content 5 | 157
hyperactivity 5 | 108
increased mean corpuscular hem... 5 | 93
decreased lean body mass 4 | 195
decreased total body fat amoun... 4 | 186
increased lean body mass 4 | 107
increased mean corpuscular vol... 4 | 91
preweaning lethality, incomple... 4 | 260
abnormal bone structure 3 | 131
abnormal retina morphology 3 | 100
decreased body length 3 | 108
decreased circulating glucose ... 3 | 121
decreased circulating serum al... 3 | 79
increased circulating alkaline... 3 | 119
increased fasted circulating g... 3 | 68
increased or absent threshold ... 3 | 128
abnormal cranium morphology 2 | 32
abnormal embryo size 2 | 112
abnormal head morphology 2 | 10
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal tail movements 2 | 12
absent pinna reflex 2 | 21
decreased caudal vertebrae num... 2 | 49
decreased circulating free fat... 2 | 39
decreased circulating total pr... 2 | 41
decreased eosinophil cell numb... 2 | 41
decreased erythrocyte cell num... 2 | 43
decreased mean corpuscular vol... 2 | 50
decreased startle reflex 2 | 48
embryonic lethality prior to t... 2 | 187
hypoactivity 2 | 89
increased exploration in new e... 2 | 56
increased heart weight 2 | 37
limb grasping 2 | 35
male infertility 2 | 62
prenatal lethality prior to he... 2 | 64
abnormal behavioral response t... 1 | 52
abnormal coat/hair pigmentatio... 1 | 54
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal head shape 1 | 4
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 35
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating phosphat... 1 | 15
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
hemorrhage 1 | 12
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 25
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
prenatal lethality 1 | 16
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46
thrombocytosis 1 | 23
tremors 1 | 34
vertebral fusion 1 | 23

Disease

ovarian cancer 140 | 8,484
medulloblastoma, large-cell 128 | 6,234
osteosarcoma 124 | 7,933
glioblastoma 115 | 5,572
psoriasis 111 | 6,685
lung cancer 91 | 4,466
atypical teratoid / rhabdoid tumor 89 | 4,369
primitive neuroectodermal tumor 72 | 3,031
oligodendroglioma 67 | 2,849
Breast cancer 66 | 3,094
malignant mesothelioma 66 | 3,162
pediatric high grade glioma 66 | 2,712
Carcinoma 61 | 2,147
pilocytic astrocytoma 61 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,988
non-small cell lung cancer 58 | 2,798
group 3 medulloblastoma 56 | 2,254
ependymoma 55 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,289
invasive ductal carcinoma 54 | 2,950
posterior fossa group B ependymoma 51 | 1,530
lung adenocarcinoma 48 | 2,713
lung carcinoma 47 | 2,844
Pick disease 45 | 1,893
colon cancer 43 | 1,475
adrenocortical carcinoma 42 | 1,427
pancreatic cancer 41 | 2,300
nasopharyngeal carcinoma 40 | 1,056
subependymal giant cell astrocytoma 40 | 2,287
astrocytic glioma 39 | 2,241
ductal carcinoma in situ 39 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,956
breast carcinoma 37 | 1,614
group 4 medulloblastoma 34 | 1,875
sonic hedgehog group medulloblastoma 34 | 1,482
adult high grade glioma 33 | 2,148
pituitary cancer 32 | 1,972
Cancer 28 | 2,346
astrocytoma 28 | 1,493
Atopic dermatitis 27 | 944
posterior fossa group A ependymoma 27 | 1,511
interstitial cystitis 26 | 2,299
medulloblastoma 26 | 1,524
Endometriosis 25 | 535
atypical teratoid/rhabdoid tumor 25 | 1,095
chronic rhinosinusitis 24 | 512
ulcerative colitis 24 | 2,087
progressive supranuclear palsy 23 | 674
juvenile dermatomyositis 22 | 1,189
tuberculosis 20 | 1,557
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
primary pancreatic ductal adenocarcinoma 19 | 1,271
Microcephaly 17 | 149
Lissencephaly 16 | 61
Multiple myeloma 16 | 1,327
acute quadriplegic myopathy 16 | 1,157
non-small cell lung carcinoma 16 | 413
spina bifida 16 | 1,064
Intellectual disability 15 | 573
dermatomyositis 15 | 933
diabetes mellitus 15 | 1,663
IGA Glomerulonephritis 14 | 454
Neurodegenerative disease 14 | 383
Primary ciliary dyskinesia 14 | 73
tuberculosis and treatment for 6 months 14 | 686
Alzheimer's disease 13 | 644
Amyotrophic Lateral Sclerosis 13 | 431
acute myeloid leukemia 13 | 780
inflammatory breast cancer 13 | 404
primary Sjogren syndrome 13 | 789
Neuroblastoma 12 | 78
Neuropathy 11 | 210
Situs Inversus 11 | 48
cutaneous lupus erythematosus 11 | 1,056
cystic fibrosis 11 | 1,665
fibroadenoma 11 | 557
hepatocellular carcinoma 11 | 532
hereditary spastic paraplegia 11 | 313
Down syndrome 10 | 548
Kaposi's sarcoma 10 | 20
Kidney cancer 10 | 118
Rheumatoid Arthritis 10 | 1,160
cystic fibrosis and chronic rhinosinusitis 10 | 213
gastric cancer 10 | 430
non primary Sjogren syndrome sicca 10 | 840
Duchenne muscular dystrophy 9 | 602
HER2-positive carcinoma of breast 9 | 10
Liposarcoma 9 | 20
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Metastatic Prostate Carcinoma 9 | 18
Nephroblastoma 9 | 45
Open-angle glaucoma 9 | 26
Rhabdomyosarcoma 9 | 29
Secondary malignant neoplasm of pancreas 9 | 10
Transitional cell carcinoma 9 | 18
active Crohn's disease 9 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
esophageal adenocarcinoma 9 | 737
gastric carcinoma 9 | 832

Tissue

Blood and immune system 276 | 17,995
Female tissues 276 | 18,647
Male tissues 276 | 17,969
Nervous System 276 | 18,561
Cardiovascular System 275 | 17,958
Digestive Tract 275 | 18,473
Endocrine System 275 | 18,512
Liver and Pancreas 274 | 18,136
Urinary Tract 274 | 18,444
Skin and soft tissues 272 | 18,115
Respiratory system 270 | 17,484

Target Family

Non-IDG 248 | 11,971
Enzyme 26 | 4,146
Kinase 4 | 634
Epigenetic 1 | 242

UniProt Keyword

Microtubule 279 | 279
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Microtubule-associated protein RP/EB family member 3 MAPRE3 Tbio Non-IDG -2.14681 132.5 161
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
Dynein light chain Tctex-type 1 DYNLT1 Tbio Non-IDG -2.32941 210.3 40
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.94177 80.5 168
Kinesin-like protein KIFC3 KIFC3 Tchem Non-IDG -1.08696 12.5 48
Dynein heavy chain 14, axonemal DNAH14 Tdark Non-IDG -0.16914 1.36 38
Tubulin beta-2A chain TUBB2A Tclin Non-IDG -1.58651 36.1 215
Retinitis pigmentosa 1-like 1 protein RP1L1 Tbio Non-IDG -1.19453 19.3 0