Development Level

Tbio 74 | 11,178
Tchem 34 | 1,885
Tclin 11 | 612
Tdark 10 | 6,569

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased blood urea nitrogen ... 3 | 51
decreased circulating triglyce... 3 | 79
hyperactivity 3 | 148
hypoactivity 3 | 132
increased leukocyte cell numbe... 3 | 47
preweaning lethality, incomple... 3 | 499
cataract 2 | 92
decreased body weight 2 | 161
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal pupil morphology 1 | 2
abnormal retina morphology 1 | 71
abnormal tibia morphology 1 | 14
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased monocyte cell number 1 | 8
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased IgA level 1 | 1
increased aggression 1 | 4
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased circulating unsatura... 1 | 1
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 88 | 11,192
psoriasis 67 | 6,514
ovarian cancer 46 | 8,297
osteosarcoma 41 | 7,766
lung cancer 39 | 4,607
medulloblastoma, large-cell 38 | 6,086
glioblastoma 37 | 5,635
Breast cancer 33 | 3,469
atypical teratoid / rhabdoid tumor 33 | 4,971
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,204
ependymoma 32 | 4,559
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,872
invasive ductal carcinoma 31 | 2,867
Cancer 30 | 2,388
interstitial cystitis 30 | 2,237
lung carcinoma 30 | 2,755
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,902
pancreatic cancer 29 | 2,322
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,911
adult high grade glioma 27 | 3,701
group 3 medulloblastoma 27 | 4,002
lung adenocarcinoma 27 | 2,627
non-small cell lung cancer 24 | 2,799
tuberculosis 24 | 1,963
Astrocytoma, Pilocytic 23 | 3,006
malignant mesothelioma 23 | 3,135
ulcerative colitis 23 | 1,765
Prostatic Neoplasms 21 | 472
cystic fibrosis 21 | 1,629
ductal carcinoma in situ 20 | 1,686
primitive neuroectodermal tumor 20 | 2,957
active Crohn's disease 18 | 882
pituitary cancer 18 | 1,915
astrocytic glioma 17 | 2,530
cutaneous lupus erythematosus 17 | 1,016
Pick disease 16 | 1,856
diabetes mellitus 16 | 1,683
oligodendroglioma 16 | 2,768
Schizophrenia 15 | 1,136
colon cancer 15 | 1,428
Chemical and Drug Induced Liver Injury 14 | 188
subependymal giant cell astrocytoma 14 | 2,230
Hypertension 13 | 372
adrenocortical carcinoma 13 | 1,385
breast carcinoma 13 | 1,589
Autosomal recessive predisposition 12 | 1,407
Kidney cancer 12 | 2,548
Liver disease 12 | 227
chronic rhinosinusitis 12 | 505
Anemia 11 | 353
Liver Cirrhosis, Experimental 11 | 733
Melanoma 11 | 689
esophageal adenocarcinoma 11 | 696
juvenile dermatomyositis 11 | 1,147
Alzheimer's disease 10 | 640
Atopic dermatitis 10 | 915
Obesity 10 | 655
acute quadriplegic myopathy 10 | 1,133
astrocytoma 10 | 1,113
nasopharyngeal carcinoma 10 | 1,024
non primary Sjogren syndrome sicca 10 | 861
Drug-Related Side Effects and Adverse Reactions 9 | 61
Sickle Cell Anemia 9 | 50
aldosterone-producing adenoma 9 | 646
Adverse reaction to drug 8 | 60
Bilirubin metabolic disorder 8 | 41
Cholestasis 8 | 154
Diarrhea 8 | 245
Endometriosis 8 | 521
non diabetic and post-ischemic heart failure 8 | 195
pancreatic carcinoma 8 | 555
Acute kidney injury 7 | 67
Adenocarcinoma 7 | 116
Breast Neoplasms 7 | 423
Coronary artery disease 7 | 253
Depressive disorder 7 | 401
Epilepsy 7 | 775
Hypertensive disease 7 | 278
Mammary Neoplasms 7 | 403
Pericholangitis 7 | 8
Rheumatoid arthritis 7 | 1,156
adrenocortical adenoma 7 | 127
gastric carcinoma 7 | 781
medulloblastoma 7 | 702
mucosa-associated lymphoid tissue lymphoma 7 | 473
pediatric high grade glioma 7 | 1,035
primary Sjogren syndrome 7 | 710
Attention deficit hyperactivity disorder 6 | 272
Cerebrovascular disease 6 | 223
Kidney disease 6 | 411
Lung Neoplasms 6 | 217
Major Depressive Disorder 6 | 293
Parkinson's disease 6 | 378
Unipolar Depression 6 | 244
active ulcerative colitis 6 | 736
fibroadenoma 6 | 538
group 4 medulloblastoma 6 | 1,806
hepatocellular carcinoma 6 | 536
primary pancreatic ductal adenocarcinoma 6 | 1,071
Asthma 5 | 370

Tissue

Liver and Pancreas 125 | 16,750
Digestive Tract 123 | 17,369
Female tissues 119 | 17,400
Skin and soft tissues 119 | 17,230
Endocrine System 118 | 18,159
Male tissues 117 | 17,142
Urinary Tract 117 | 16,678
Blood and immune system 109 | 16,909
Respiratory system 106 | 16,393
Nervous System 102 | 16,725
Cardiovascular System 87 | 15,192

Target Family

Enzyme 81 | 4,145
Non-IDG 42 | 12,091
Kinase 3 | 634
Ion Channel 2 | 344
Transcription Factor 1 | 1,400

UniProt Keyword

Microsome 129 | 129
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 2A13 CYP2A13 Tbio Non-IDG -2.14858 139.9 122
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.65839 4688.0 397
Steroid 21-hydroxylase CYP21A2 Tbio Enzyme 0.00000 214
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.93702 904.4 260
Vitamin D 25-hydroxylase CYP2R1 Tbio Enzyme -1.96830 95.4 152
Ryanodine receptor 3 RYR3 Tclin Ion Channel -2.15460 142.3 16
Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 Tchem Enzyme -3.04846 1171.6 189
Phylloquinone omega-hydroxylase CYP4F2 CYP4F2 Tbio Enzyme -2.16137 145.5 83
UDP-glucuronosyltransferase 1-7 UGT1A7 Tbio Enzyme -1.87803 74.6 24
UDP-glucuronosyltransferase 1-8 UGT1A8 Tbio Enzyme -1.68933 43.9 5