Development Level

Tbio 72 | 10,625
Tchem 33 | 1,890
Tclin 12 | 602
Tdark 11 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased circulating triglyce... 3 | 83
preweaning lethality, incomple... 3 | 260
abnormal retina morphology 2 | 100
decreased blood urea nitrogen ... 2 | 31
decreased body weight 2 | 174
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hyperactivity 2 | 108
increased circulating potassiu... 2 | 31
thrombocytopenia 2 | 46
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal gait 1 | 51
abnormal locomotor activation 1 | 26
abnormal retinal pigmentation 1 | 61
abnormal tibia morphology 1 | 14
decreased B cell number 1 | 30
decreased body length 1 | 108
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased pro-B cell number 1 | 2
decreased startle reflex 1 | 48
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
increased IgA level 1 | 1
increased aggression 1 | 2
increased bone mineral content 1 | 92
increased circulating LDL chol... 1 | 15
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased pro-B cell number 1 | 1
increased startle reflex 1 | 38
limb grasping 1 | 35
mydriasis 1 | 9
preweaning lethality, complete... 1 | 633

Disease

psoriasis 71 | 6,685
ovarian cancer 52 | 8,484
osteosarcoma 44 | 7,933
lung cancer 42 | 4,466
medulloblastoma, large-cell 42 | 6,234
glioblastoma 38 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,956
invasive ductal carcinoma 33 | 2,950
Breast cancer 32 | 3,094
Cancer 32 | 2,346
atypical teratoid / rhabdoid tumor 32 | 4,369
interstitial cystitis 32 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,988
lung carcinoma 31 | 2,844
pancreatic cancer 30 | 2,300
lung adenocarcinoma 29 | 2,713
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,795
ulcerative colitis 29 | 2,087
pilocytic astrocytoma 25 | 3,086
malignant mesothelioma 24 | 3,162
non-small cell lung cancer 24 | 2,798
pediatric high grade glioma 24 | 2,712
cystic fibrosis 22 | 1,665
primitive neuroectodermal tumor 22 | 3,031
Prostatic Neoplasms 21 | 471
ductal carcinoma in situ 21 | 1,745
oligodendroglioma 21 | 2,849
active Crohn's disease 20 | 918
pituitary cancer 19 | 1,972
Pick disease 18 | 1,893
cutaneous lupus erythematosus 18 | 1,056
tuberculosis 18 | 1,557
ependymoma 17 | 2,514
posterior fossa group A ependymoma 17 | 1,511
astrocytic glioma 16 | 2,241
group 3 medulloblastoma 16 | 2,254
subependymal giant cell astrocytoma 16 | 2,287
colon cancer 15 | 1,475
diabetes mellitus 15 | 1,663
adrenocortical carcinoma 14 | 1,427
breast carcinoma 14 | 1,614
adult high grade glioma 13 | 2,148
astrocytoma 13 | 1,493
acute quadriplegic myopathy 12 | 1,157
chronic rhinosinusitis 12 | 512
juvenile dermatomyositis 12 | 1,189
Liver disease 11 | 219
Peripheral Neuropathy 11 | 303
esophageal adenocarcinoma 11 | 737
group 4 medulloblastoma 11 | 1,875
non primary Sjogren syndrome sicca 11 | 840
sonic hedgehog group medulloblastoma 11 | 1,482
Atopic dermatitis 10 | 944
Drug-Induced Liver Injury 10 | 118
Hypertension 10 | 287
Alzheimer's disease 9 | 644
Anemia 9 | 252
Obesity 9 | 616
aldosterone-producing adenoma 9 | 664
nasopharyngeal carcinoma 9 | 1,056
Adverse reaction to drug 8 | 54
Bilirubin metabolic disorder 8 | 39
Endometriosis 8 | 535
Lung Neoplasms 8 | 171
Mammary Neoplasms 8 | 410
Rheumatoid Arthritis 8 | 1,160
medulloblastoma 8 | 1,524
non diabetic and post-ischemic heart failure 8 | 200
pancreatic carcinoma 8 | 567
posterior fossa group B ependymoma 8 | 1,530
primary pancreatic ductal adenocarcinoma 8 | 1,271
Acute kidney injury 7 | 65
Adenocarcinoma 7 | 115
Coronary artery disease 7 | 240
Diarrhea 7 | 155
Multiple myeloma 7 | 1,327
Pericholangitis 7 | 7
Schizophrenia 7 | 501
adrenocortical adenoma 7 | 134
atypical teratoid/rhabdoid tumor 7 | 1,095
dermatomyositis 7 | 933
fibroadenoma 7 | 557
gastric carcinoma 7 | 832
hepatocellular carcinoma 7 | 532
mucosa-associated lymphoid tissue lymphoma 7 | 480
primary Sjogren syndrome 7 | 789
Attention deficit hyperactivity disorder 6 | 156
Cerebrovascular disease 6 | 231
Down syndrome 6 | 548
Epilepsy 6 | 346
IGA Glomerulonephritis 6 | 454
Kidney disease 6 | 396
Liver carcinoma 6 | 217
Parkinson's disease 6 | 364
Waldenstrons macroglobulinemia 6 | 765
Asthma 5 | 349
gastric cancer 5 | 430
nephrosclerosis 5 | 329
spina bifida 5 | 1,064

Tissue

Liver and Pancreas 126 | 18,136
Digestive Tract 125 | 18,473
Urinary Tract 125 | 18,444
Blood and immune system 123 | 17,995
Female tissues 121 | 18,647
Endocrine System 120 | 18,512
Nervous System 120 | 18,561
Skin and soft tissues 120 | 18,115
Male tissues 118 | 17,969
Cardiovascular System 114 | 17,958
Respiratory system 114 | 17,484

Target Family

Enzyme 80 | 4,146
Non-IDG 42 | 11,971
Kinase 3 | 634
Ion Channel 2 | 341
Transcription Factor 1 | 1,400

UniProt Keyword

Microsome 128 | 128
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dimethylaniline monooxygenase [N-oxide-forming] 5 FMO5 Tbio Enzyme -0.93021 9.11 128
Adenosylhomocysteinase 2 AHCYL1 Tchem Enzyme -1.57893 43.2 102
24-hydroxycholesterol 7-alpha-hydroxylase CYP39A1 Tbio Enzyme -0.95411 6.43 97
Cytochrome b5 CYB5A Tchem Non-IDG -3.24788 1711.2 249
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.20847 1594.9 391
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
Retinol dehydrogenase 10 RDH10 Tbio Enzyme -1.34654 27.5 95
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -1.98060 100.6 25
UDP-glucuronosyltransferase 2B10 UGT2B10 Tchem Enzyme -1.11329 16.8 81
Delta(14)-sterol reductase TM7SF2 Tbio Enzyme -1.04299 12.4 80