Development Level

Tbio 86 | 10,625
Tdark 65 | 7,003
Tchem 30 | 1,890
Tclin 4 | 602

IMPC Term

abnormal behavior 8 | 226
decreased total body fat amoun... 8 | 186
increased grip strength 7 | 83
preweaning lethality, complete... 7 | 633
increased lean body mass 6 | 107
decreased lean body mass 5 | 195
increased sacral vertebrae num... 5 | 62
abnormal bone structure 4 | 131
decreased circulating HDL chol... 4 | 77
preweaning lethality, incomple... 4 | 260
abnormal retina morphology 3 | 100
abnormal retinal pigmentation 3 | 61
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased circulating serum al... 3 | 79
hyperactivity 3 | 108
increased total body fat amoun... 3 | 57
male infertility 3 | 62
short tibia 3 | 82
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal gait 2 | 51
abnormal rib morphology 2 | 28
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating chloride... 2 | 32
decreased circulating fructosa... 2 | 31
decreased hemoglobin content 2 | 53
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased rib number 2 | 59
embryonic lethality prior to t... 2 | 187
female infertility 2 | 34
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased circulating HDL chol... 2 | 63
increased circulating creatini... 2 | 29
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 24
increased mean platelet volume 2 | 19
increased or absent threshold ... 2 | 128
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal heart left ventricle ... 1 | 20
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal pancreas morphology 1 | 6
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
corneal opacity 1 | 25
decreased B cell number 1 | 30
decreased circulating calcium ... 1 | 33
decreased circulating glycerol... 1 | 19
decreased circulating thyroxin... 1 | 5
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased pulmonary respirator... 1 | 4
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
enlarged spleen 1 | 26
hydrometra 1 | 13
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased cardiac muscle contr... 1 | 5
increased circulating LDL chol... 1 | 15
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating glycerol... 1 | 11
increased circulating potassiu... 1 | 31
increased mean corpuscular hem... 1 | 93
increased prepulse inhibition 1 | 21
increased red blood cell distr... 1 | 21
polydactyly 1 | 22
premature death 1 | 5
small testis 1 | 37
straub tail 1 | 26
tremors 1 | 34

Disease

osteosarcoma 92 | 7,933
ovarian cancer 88 | 8,484
medulloblastoma, large-cell 52 | 6,234
psoriasis 48 | 6,685
glioblastoma 43 | 5,572
malignant mesothelioma 39 | 3,162
atypical teratoid / rhabdoid tumor 38 | 4,369
group 3 medulloblastoma 36 | 2,254
lung cancer 35 | 4,466
primitive neuroectodermal tumor 32 | 3,031
Cancer 31 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
Breast cancer 25 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,988
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,795
Pick disease 21 | 1,893
adult high grade glioma 21 | 2,148
ependymoma 21 | 2,514
invasive ductal carcinoma 21 | 2,950
non-small cell lung cancer 21 | 2,798
pilocytic astrocytoma 20 | 3,086
Carcinoma 19 | 2,147
oligodendroglioma 18 | 2,849
pediatric high grade glioma 17 | 2,712
astrocytic glioma 16 | 2,241
lung adenocarcinoma 16 | 2,713
pancreatic cancer 16 | 2,300
Intellectual disability 15 | 573
spina bifida 15 | 1,064
subependymal giant cell astrocytoma 15 | 2,287
tuberculosis and treatment for 6 months 13 | 686
Mammary Neoplasms 12 | 410
Multiple myeloma 12 | 1,327
atypical teratoid/rhabdoid tumor 12 | 1,095
group 4 medulloblastoma 12 | 1,875
juvenile dermatomyositis 12 | 1,189
medulloblastoma 12 | 1,524
pituitary cancer 12 | 1,972
ductal carcinoma in situ 11 | 1,745
hepatocellular carcinoma 11 | 532
posterior fossa group B ependymoma 11 | 1,530
Rheumatoid Arthritis 10 | 1,160
acute myeloid leukemia 10 | 780
acute quadriplegic myopathy 10 | 1,157
adrenocortical carcinoma 10 | 1,427
dermatomyositis 10 | 933
lung carcinoma 10 | 2,844
posterior fossa group A ependymoma 10 | 1,511
progressive supranuclear palsy 10 | 674
sonic hedgehog group medulloblastoma 10 | 1,482
tuberculosis 10 | 1,557
Waldenstrons macroglobulinemia 9 | 765
interstitial cystitis 9 | 2,299
diabetes mellitus 8 | 1,663
gastric cancer 8 | 430
astrocytoma 7 | 1,493
breast carcinoma 7 | 1,614
cystic fibrosis 7 | 1,665
non primary Sjogren syndrome sicca 7 | 840
ulcerative colitis 7 | 2,087
Down syndrome 6 | 548
Liver carcinoma 6 | 217
Prostatic Neoplasms 6 | 471
Schizophrenia 6 | 501
colon cancer 6 | 1,475
Alzheimer's disease 5 | 644
IGA Glomerulonephritis 5 | 454
Leukemia, Myelocytic, Acute 5 | 113
Stomach Neoplasms 5 | 282
gastric carcinoma 5 | 832
nasopharyngeal carcinoma 5 | 1,056
primary Sjogren syndrome 5 | 789
primary pancreatic ductal adenocarcinoma 5 | 1,271
Adenoid Cystic Carcinoma 4 | 99
Amyotrophic Lateral Sclerosis 4 | 431
Autistic Disorder 4 | 320
Bladder Neoplasm 4 | 109
Cleft Lip 4 | 91
Cleft palate 4 | 125
Leukemia 4 | 88
Lymphoma, Follicular 4 | 20
Male infertility 4 | 170
Peripheral Neuropathy 4 | 303
active Crohn's disease 4 | 918
aldosterone-producing adenoma 4 | 664
pancreatic carcinoma 4 | 567
Amphetamine-Related Disorders 3 | 74
Atopic dermatitis 3 | 944
Becker muscular dystrophy 3 | 187
Crohn's disease 3 | 304
Duchenne muscular dystrophy 3 | 602
Microcephaly 3 | 149
Neuropathy 3 | 210
Polycystic Ovary Syndrome 3 | 332
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,056
cystic fibrosis and chronic rhinosinusitis 3 | 213
head and neck cancer 3 | 270

Tissue

Endocrine System 179 | 18,512
Female tissues 179 | 18,647
Nervous System 179 | 18,561
Urinary Tract 179 | 18,444
Cardiovascular System 178 | 17,958
Digestive Tract 178 | 18,473
Skin and soft tissues 178 | 18,115
Blood and immune system 177 | 17,995
Liver and Pancreas 177 | 18,136
Respiratory system 175 | 17,484
Male tissues 174 | 17,969

Target Family

Enzyme 117 | 4,146
Epigenetic 43 | 242
TF/Epigenetic 15 | 38
Non-IDG 10 | 11,971

UniProt Keyword

Methyltransferase 185 | 185
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.20916 14.6 78
Putative methyltransferase NSUN7 NSUN7 Tdark Enzyme -0.64137 4.34 10
SET domain-containing protein 9 SETD9 Tdark Non-IDG 0.21 0.40 71
Transmembrane O-methyltransferase LRTOMT Tbio Enzyme 13.4 29
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.53375 346.3 108
rRNA 2'-O-methyltransferase fibrillarin FBL Tbio Enzyme -3.17750 1580.2 240
Protein-L-isoaspartate(D-aspartate) O-methyltransferase PCMT1 Tbio Enzyme -1.78815 65.1 138
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase NOP2 Tbio Enzyme -1.48238 28.2 66
Histone-lysine N-methyltransferase 2E KMT2E Tbio Epigenetic -1.45323 38.7 150
Phenylethanolamine N-methyltransferase PNMT Tchem Enzyme -2.88545 840.4 235