Development Level

Tbio 61 | 11,445
Tdark 23 | 6,588
Tchem 6 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

male infertility 10 | 123
female infertility 7 | 60
decreased bone mineral content 5 | 151
decreased bone mineral density 3 | 126
decreased mean corpuscular hem... 3 | 50
improved glucose tolerance 3 | 79
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 31
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
increased blood urea nitrogen ... 2 | 48
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
preweaning lethality, complete... 2 | 979
shortened RR interval 2 | 17
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal ovary morphology 1 | 7
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal thymus morphology 1 | 7
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged thymus 1 | 5
hyperactivity 1 | 148
hypoactivity 1 | 132
increased basophil cell number 1 | 7
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened ST segment 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 64 | 11,493
osteosarcoma 36 | 7,950
ovarian cancer 28 | 8,520
medulloblastoma, large-cell 27 | 6,241
group 3 medulloblastoma 26 | 4,104
psoriasis 26 | 6,694
glioblastoma 25 | 5,792
Infertility 20 | 188
Kidney cancer 20 | 2,613
Male infertility 20 | 206
atypical teratoid / rhabdoid tumor 20 | 5,112
ependymoma 18 | 4,679
Breast cancer 17 | 3,578
primitive neuroectodermal tumor 17 | 3,035
Cancer 15 | 2,499
adult high grade glioma 13 | 3,801
lung cancer 13 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung adenocarcinoma 12 | 2,716
malignant mesothelioma 12 | 3,232
Astrocytoma, Pilocytic 10 | 3,081
Autosomal recessive predisposition 9 | 1,442
Azoospermia 9 | 110
Premature ovarian failure 9 | 65
colon cancer 9 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
non-small cell lung cancer 9 | 2,890
adrenocortical carcinoma 8 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
Dull intelligence 7 | 645
Intellectual disability 7 | 1,016
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
astrocytic glioma 7 | 2,597
ductal carcinoma in situ 7 | 1,745
pancreatic cancer 7 | 2,398
Rheumatoid arthritis 6 | 1,191
Short stature 6 | 531
Small head 6 | 374
Waldenstrons macroglobulinemia 6 | 765
group 4 medulloblastoma 6 | 1,855
nasopharyngeal carcinoma 6 | 1,058
pituitary cancer 6 | 1,972
subependymal giant cell astrocytoma 6 | 2,287
Endometriosis 5 | 540
Hypoplastic mandible condyle 5 | 275
Mandibular hypoplasia 5 | 275
Melanoma 5 | 711
Micrognathism 5 | 275
Multiple myeloma 5 | 1,332
Nijmegen breakage syndrome 5 | 24
acute quadriplegic myopathy 5 | 1,158
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
ulcerative colitis 5 | 1,819
Ataxia telangiectasia 4 | 34
Atopic dermatitis 4 | 952
Attention deficit hyperactivity disorder 4 | 278
Delayed bone age 4 | 136
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Microcephaly 4 | 166
Premature Menopause 4 | 31
Prostatic Neoplasms 4 | 495
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
gastric carcinoma 4 | 807
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
Anteverted nostril 3 | 191
Asthma 3 | 385
Bilateral fifth finger clinodactyly 3 | 110
Bladder Neoplasm 3 | 112
Cognitive delay 3 | 608
Concave bridge of nose 3 | 195
Congenital hypoplasia of penis 3 | 176
Curvature of little finger 3 | 110
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Endometrial cancer 3 | 311
Glaucoma 3 | 239
Global developmental delay 3 | 608
Liver cancer 3 | 604
Mental and motor retardation 3 | 608
Myeloid Leukemia 3 | 19
Short neck 3 | 140
Urinary Bladder Neoplasms 3 | 114
atypical teratoid/rhabdoid tumor 3 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
posterior fossa group B ependymoma 3 | 416
tuberculosis 3 | 2,010

Tissue

Endocrine System 90 | 18,159
Female tissues 83 | 17,400
Skin and soft tissues 81 | 17,230
Digestive Tract 80 | 17,369
Male tissues 78 | 17,142
Blood and immune system 77 | 16,909
Nervous System 76 | 16,725
Liver and Pancreas 73 | 16,750
Urinary Tract 72 | 16,678
Respiratory system 70 | 16,393
Cardiovascular System 58 | 15,192

Target Family

Non-IDG 66 | 12,091
Enzyme 12 | 4,145
Epigenetic 5 | 242
Kinase 4 | 634
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400
Transporter 1 | 473

UniProt Keyword

Meiosis 90 | 90
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meiosis-specific protein MEI4 MEI4 Tdark Non-IDG 0.00000 7
Testis anion transporter 1 SLC26A8 Tbio Transporter -0.96605 9.56 60
HORMA domain-containing protein 1 HORMAD1 Tbio Non-IDG -1.44656 27.9 135
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.33263 208.9 148
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 ASZ1 Tbio Non-IDG -2.81661 644.9 107
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
Meiosis regulator and mRNA stability factor 1 MARF1 Tdark Non-IDG -0.82344 7.58 23
Cohesin subunit SA-3 STAG3 Tbio Non-IDG -1.30055 20.0 104
ATP-dependent RNA helicase TDRD9 TDRD9 Tbio Epigenetic -0.66287 3.88 43
Meiosis-specific nuclear structural protein 1 MNS1 Tbio Non-IDG -1.18603 14.1 68