Development Level

Tbio 76 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal skin morphology 1 | 50
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74

Disease

Cancer 73 | 2,499
Ankylosing spondylitis 71 | 140
Behcet's disease 70 | 89
diabetes mellitus 58 | 1,728
Acquired immunodeficiency syndrome 57 | 197
Arthritis 57 | 290
Hypersensitivity reaction type II disease 57 | 253
Uveitis 57 | 103
Herpes zoster 56 | 68
Juvenile rheumatoid arthritis 56 | 111
psoriasis 52 | 6,694
Stevens-Johnson syndrome 50 | 92
Human immunodeficiency virus infectious disease 49 | 138
Psoriatic arthritis 49 | 86
dermatomyositis 39 | 966
Carcinoma 37 | 11,493
Rheumatoid arthritis 36 | 1,191
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Dermatitis 35 | 157
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
Anemia 23 | 365
Hemochromatosis 23 | 54
Kidney disease 22 | 430
Liver disease 22 | 237
Birdshot chorioretinopathy 21 | 23
Hepatitis B 21 | 108
Leprosy 21 | 73
Multiple Sclerosis 21 | 540
Primary immunodeficiency disease 21 | 54
Skin disease 21 | 66
tuberculosis 21 | 2,010
Pre-Eclampsia 15 | 68
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
ovarian cancer 7 | 8,520
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
juvenile dermatomyositis 6 | 1,187
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
cutaneous lupus erythematosus 5 | 1,057
lung carcinoma 5 | 2,843
osteosarcoma 5 | 7,950
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
Glioma 3 | 74
astrocytoma 3 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
Adverse reaction to drug 2 | 61
Bipolar Disorder 2 | 666
Chemical and Drug Induced Liver Injury 2 | 195
Drug-Related Side Effects and Adverse Reactions 2 | 62
Duchenne muscular dystrophy 2 | 601
Exanthema 2 | 43
Gastrointestinal Hemorrhage 2 | 52
Genetic Predisposition to Disease 2 | 27
HIV Infections 2 | 102
Inflammatory abnormality of the eye 2 | 10
Parapsoriasis 2 | 6
Photodysphoria 2 | 121
Photophobia 2 | 121
Proteinuria 2 | 144
Psychotic Disorders 2 | 151
Weight decreased 2 | 103
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
inflammatory breast cancer 2 | 286
interstitial cystitis 2 | 2,312
limb girdle muscular dystrophy 2I 2 | 32
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormal respiratory patterns 1 | 20
Acne 1 | 52
Amyloidosis 1 | 67
Confusion 1 | 21
Diffuse large B-cell lymphoma 1 | 39
Edema 1 | 81
Heart Diseases 1 | 43
Hematuria 1 | 36
Hemiparesis 1 | 34
Idiopathic pulmonary arterial hypertension 1 | 40
Lymphatic system disease 1 | 15
Macroglobulinemia 1 | 18
Myasthenia gravis 1 | 23
Urinary tract obstruction 1 | 11

Tissue

Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Respiratory system 7 | 16,393
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 76 | 12,091

UniProt Keyword

MHC I 76 | 76
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

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