Development Level

Tbio 92 | 11,445
Tclin 23 | 613
Tchem 19 | 1,598
Tdark 17 | 6,588

IMPC Phenotype

abnormal behavior 5 | 298
preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
decreased bone mineral density 3 | 126
enlarged heart 3 | 210
abnormal QT variability 2 | 10
abnormal heart morphology 2 | 162
decreased body length 2 | 101
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal male genitalia morpho... 1 | 3
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
brachydactyly 1 | 19
cataract 1 | 92
decreased IgM level 1 | 1
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating lipase l... 1 | 3
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
oligodactyly 1 | 1
polydactyly 1 | 7
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small kidney 1 | 16
syndactyly 1 | 23
thin ventricular wall 1 | 24

Disease

Carcinoma 92 | 11,493
ovarian cancer 74 | 8,520
osteosarcoma 54 | 7,950
lung cancer 51 | 4,740
psoriasis 51 | 6,694
medulloblastoma, large-cell 48 | 6,241
Autosomal recessive predisposition 42 | 1,442
atypical teratoid / rhabdoid tumor 41 | 5,112
group 3 medulloblastoma 39 | 4,104
glioblastoma 37 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,962
ependymoma 32 | 4,679
invasive ductal carcinoma 32 | 2,951
adult high grade glioma 29 | 3,801
non-small cell lung cancer 29 | 2,890
malignant mesothelioma 27 | 3,232
tuberculosis 27 | 2,010
Breast cancer 26 | 3,578
lung adenocarcinoma 26 | 2,716
lung carcinoma 26 | 2,843
Epilepsy 24 | 792
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
primitive neuroectodermal tumor 23 | 3,035
Cancer 22 | 2,499
astrocytic glioma 22 | 2,597
oligodendroglioma 22 | 2,850
Astrocytoma, Pilocytic 21 | 3,081
subependymal giant cell astrocytoma 21 | 2,287
ulcerative colitis 21 | 1,819
pancreatic cancer 20 | 2,398
Multiple myeloma 19 | 1,332
Seizures 19 | 596
colon cancer 19 | 1,478
interstitial cystitis 19 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
pituitary cancer 18 | 1,972
Kidney cancer 17 | 2,613
ductal carcinoma in situ 17 | 1,745
Cognitive delay 16 | 608
Global developmental delay 16 | 608
Mental and motor retardation 16 | 608
Intellectual disability 15 | 1,016
Pick disease 15 | 1,894
breast carcinoma 15 | 1,638
Schizophrenia 14 | 1,160
adrenocortical carcinoma 14 | 1,428
Liver Cirrhosis, Experimental 13 | 769
Muscle hypotonia 13 | 571
cystic fibrosis 13 | 1,696
diabetes mellitus 13 | 1,728
Bipolar Disorder 12 | 666
astrocytoma 12 | 1,146
gastric carcinoma 12 | 807
Failure to gain weight 11 | 365
Pediatric failure to thrive 11 | 365
Waldenstrons macroglobulinemia 11 | 765
Dull intelligence 10 | 645
Liver carcinoma 10 | 240
Low intelligence 10 | 645
Melanoma 10 | 711
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Osteoporosis 10 | 363
Poor school performance 10 | 645
Short stature 10 | 531
active ulcerative colitis 10 | 764
Carcinoma, Hepatocellular 9 | 228
Glaucoma 9 | 239
Infantile onset 9 | 238
Obesity 9 | 678
active Crohn's disease 9 | 922
aldosterone-producing adenoma 9 | 665
cutaneous lupus erythematosus 9 | 1,057
group 4 medulloblastoma 9 | 1,855
nephrosclerosis 9 | 333
spina bifida 9 | 1,074
Adenocarcinoma of lung 8 | 142
Hepatomegaly 8 | 285
Hypertension 8 | 396
Major Depressive Disorder 8 | 301
Metabolic acidosis 8 | 90
Stomach Neoplasms 8 | 300
acute quadriplegic myopathy 8 | 1,158
dermatomyositis 8 | 966
Cerebral atrophy 7 | 178
Depressive disorder 7 | 409
Down syndrome 7 | 499
Hypoglycemia 7 | 152
Neurodegenerative disease 7 | 414
Nystagmus 7 | 317
Small head 7 | 374
pancreatic carcinoma 7 | 562
pediatric high grade glioma 7 | 1,064
Atopic dermatitis 6 | 952
Mental Depression 6 | 333
Prostatic Neoplasms 6 | 495
acute myeloid leukemia 6 | 783
progressive supranuclear palsy 6 | 676
sonic hedgehog group medulloblastoma 6 | 467

Tissue

Endocrine System 148 | 18,159
Digestive Tract 146 | 17,369
Female tissues 145 | 17,400
Male tissues 145 | 17,142
Skin and soft tissues 145 | 17,230
Blood and immune system 144 | 16,909
Nervous System 143 | 16,725
Liver and Pancreas 142 | 16,750
Urinary Tract 141 | 16,678
Respiratory system 138 | 16,393
Cardiovascular System 131 | 15,192

Target Family

Enzyme 133 | 4,145
Non-IDG 10 | 12,091
Kinase 7 | 634
Epigenetic 1 | 242

UniProt Keyword

Lyase 151 | 151
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carbonic anhydrase 12 CA12 Tclin Enzyme -2.28368 173.2 309
Vitamin K-dependent gamma-carboxylase GGCX Tclin Enzyme -1.90296 79.3 192
Adenylate cyclase type 10 ADCY10 Tchem Enzyme -3.13751 1324.4 108
Ethylmalonyl-CoA decarboxylase ECHDC1 Tbio Enzyme -2.16398 143.2 102
S-adenosylmethionine decarboxylase proenzyme AMD1 Tchem Enzyme -3.21826 1586.8 141
Deoxyribose-phosphate aldolase DERA Tbio Enzyme -2.21374 155.0 69
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Nucleic acid dioxygenase ALKBH1 ALKBH1 Tbio Enzyme -2.09946 119.6 149
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.21106 157.2 307
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 Tbio Enzyme -1.13540 12.8 55