Development Level

Tbio 144 | 10,625
Tchem 33 | 1,890
Tdark 21 | 7,003
Tclin 9 | 602

IMPC Term

preweaning lethality, complete... 6 | 633
increased or absent threshold ... 5 | 128
preweaning lethality, incomple... 5 | 260
decreased lean body mass 4 | 195
decreased rib number 4 | 59
hypoactivity 4 | 89
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased body length 3 | 108
decreased body weight 3 | 174
decreased circulating glucose ... 3 | 121
decreased grip strength 3 | 123
decreased lumbar vertebrae num... 3 | 62
decreased threshold for audito... 3 | 32
enlarged heart 3 | 111
increased body weight 3 | 42
abnormal lens morphology 2 | 73
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased mean corpuscular hem... 2 | 19
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased total body fat amoun... 2 | 186
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased hematocrit 2 | 36
increased sacral vertebrae num... 2 | 62
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal eye anterior chamber ... 1 | 3
abnormal hair growth 1 | 8
abnormal iris morphology 1 | 12
abnormal liver morphology 1 | 5
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal tibia morphology 1 | 14
abnormal vertebrae morphology 1 | 14
absent pinna reflex 1 | 21
absent startle reflex 1 | 15
cataract 1 | 26
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating fructosa... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased lactate dehydrogenas... 1 | 14
decreased mean corpuscular hem... 1 | 34
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
decreased thoracic vertebrae n... 1 | 7
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased CD4-positive, alpha ... 1 | 15
increased Ly6C high monocyte n... 1 | 12
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased fasted circulating g... 1 | 68
increased mean corpuscular vol... 1 | 91
increased memory CD4-positive,... 1 | 3
irregularly shaped pupil 1 | 7
persistence of hyaloid vascula... 1 | 22
short tibia 1 | 82
shortened ST segment 1 | 9
vertebral fusion 1 | 23

Disease

ovarian cancer 102 | 8,484
osteosarcoma 94 | 7,933
psoriasis 87 | 6,685
glioblastoma 73 | 5,572
medulloblastoma, large-cell 69 | 6,234
atypical teratoid / rhabdoid tumor 57 | 4,369
lung cancer 54 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,289
Breast cancer 42 | 3,094
malignant mesothelioma 42 | 3,162
invasive ductal carcinoma 40 | 2,950
pediatric high grade glioma 40 | 2,712
pilocytic astrocytoma 38 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
interstitial cystitis 36 | 2,299
lung carcinoma 35 | 2,844
oligodendroglioma 35 | 2,849
subependymal giant cell astrocytoma 35 | 2,287
primitive neuroectodermal tumor 34 | 3,031
Cancer 31 | 2,346
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,795
astrocytic glioma 30 | 2,241
non-small cell lung cancer 30 | 2,798
diabetes mellitus 29 | 1,663
ependymoma 29 | 2,514
ductal carcinoma in situ 27 | 1,745
lung adenocarcinoma 27 | 2,713
ulcerative colitis 27 | 2,087
adult high grade glioma 25 | 2,148
group 3 medulloblastoma 25 | 2,254
pancreatic cancer 24 | 2,300
pituitary cancer 24 | 1,972
Carcinoma 23 | 2,147
Pick disease 22 | 1,893
astrocytoma 21 | 1,493
cystic fibrosis 21 | 1,665
group 4 medulloblastoma 21 | 1,875
posterior fossa group A ependymoma 20 | 1,511
breast carcinoma 19 | 1,614
adrenocortical carcinoma 18 | 1,427
tuberculosis 18 | 1,557
Atopic dermatitis 17 | 944
Multiple myeloma 16 | 1,327
Obesity 16 | 616
primary pancreatic ductal adenocarcinoma 16 | 1,271
spina bifida 16 | 1,064
atypical teratoid/rhabdoid tumor 15 | 1,095
colon cancer 15 | 1,475
cutaneous lupus erythematosus 15 | 1,056
Alzheimer's disease 14 | 644
Prostatic Neoplasms 14 | 471
medulloblastoma 14 | 1,524
primary Sjogren syndrome 14 | 789
Endometriosis 13 | 535
non primary Sjogren syndrome sicca 13 | 840
posterior fossa group B ependymoma 13 | 1,530
sonic hedgehog group medulloblastoma 13 | 1,482
Waldenstrons macroglobulinemia 12 | 765
Down syndrome 11 | 548
IGA Glomerulonephritis 11 | 454
Rheumatoid Arthritis 11 | 1,160
acute quadriplegic myopathy 11 | 1,157
juvenile dermatomyositis 11 | 1,189
active Crohn's disease 10 | 918
acute myeloid leukemia 10 | 780
progressive supranuclear palsy 10 | 674
Atherosclerosis 9 | 275
Coronary artery disease 9 | 240
Crohn's disease 9 | 304
gastric carcinoma 9 | 832
Hypertensive disease 8 | 193
Mammary Neoplasms 8 | 410
Metabolic syndrome X 8 | 155
dermatomyositis 8 | 933
mucosa-associated lymphoid tissue lymphoma 8 | 480
nasopharyngeal carcinoma 8 | 1,056
pancreatic carcinoma 8 | 567
Animal Mammary Neoplasms 7 | 136
Duchenne muscular dystrophy 7 | 602
Infertility 7 | 163
Mammary Neoplasms, Experimental 7 | 150
Menopausal flushing 7 | 17
Polycystic Ovary Syndrome 7 | 332
Adenoma 6 | 165
Amyotrophic Lateral Sclerosis 6 | 431
Asthma 6 | 349
Atrophic vaginitis 6 | 14
Autistic Disorder 6 | 320
Heart disease 6 | 279
Hypertension 6 | 287
Intellectual disability 6 | 573
Multiple Sclerosis 6 | 498
Parkinson's disease 6 | 364
Prostate cancer 6 | 172
Vascular disease 6 | 281
aldosterone-producing adenoma 6 | 664
chronic rhinosinusitis 6 | 512
nephrosclerosis 6 | 329
tuberculosis and treatment for 6 months 6 | 686

Tissue

Digestive Tract 205 | 18,473
Endocrine System 205 | 18,512
Liver and Pancreas 205 | 18,136
Nervous System 205 | 18,561
Female tissues 204 | 18,647
Skin and soft tissues 204 | 18,115
Blood and immune system 203 | 17,995
Cardiovascular System 203 | 17,958
Urinary Tract 203 | 18,444
Respiratory system 202 | 17,484
Male tissues 201 | 17,969

Target Family

Non-IDG 161 | 11,971
Enzyme 19 | 4,146
Kinase 10 | 634
Nuclear Receptor 9 | 48
GPCR 7 | 406
Epigenetic 1 | 242

UniProt Keyword

Lipid-binding 207 | 207
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516
C2 domain-containing protein 5 C2CD5 Tbio Non-IDG 0.27 0.49 34
Gastrotropin FABP6 Tbio Non-IDG -2.14251 142.9 116
PH and SEC7 domain-containing protein 4 PSD4 Tdark Non-IDG -0.79827 6.91 21
Fatty acid-binding protein, intestinal FABP2 Tchem Non-IDG -2.48234 381.1 342
Guanine nucleotide exchange factor DBS MCF2L Tbio Non-IDG -0.93602 11.4 104
Fatty acid-binding protein, brain FABP7 Tchem Non-IDG -2.12234 145.0 346
ATP synthase F(0) complex subunit C2, mitochondrial ATP5G2 Tbio Enzyme -1.03087 9.31 110
Profilin-4 PFN4 Tdark Non-IDG -0.52386 3.41 21