Development Level

Tbio 85 | 11,445
Tdark 9 | 6,588
Tchem 7 | 1,598
Tclin 2 | 613

IMPC Phenotype

increased bone mineral density 4 | 72
preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
decreased erythrocyte cell num... 3 | 62
hypoactivity 3 | 132
increased mean corpuscular vol... 3 | 92
abnormal behavior 2 | 298
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal retina morphology 2 | 71
decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
enlarged epididymis 2 | 31
enlarged heart 2 | 210
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 36
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
abnormal QT variability 1 | 10
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal eye pigmentation 1 | 3
abnormal eye size 1 | 7
abnormal eyelid aperture 1 | 2
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
absent pinna reflex 1 | 23
anophthalmia 1 | 33
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged testis 1 | 6
excessive tearing 1 | 2
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
limb grasping 1 | 41
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
trunk curl 1 | 16

Disease

Carcinoma 69 | 11,493
ovarian cancer 53 | 8,520
psoriasis 47 | 6,694
osteosarcoma 45 | 7,950
glioblastoma 36 | 5,792
medulloblastoma, large-cell 35 | 6,241
lung cancer 31 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
ependymoma 28 | 4,679
invasive ductal carcinoma 28 | 2,951
atypical teratoid / rhabdoid tumor 27 | 5,112
Kidney cancer 24 | 2,613
lung carcinoma 23 | 2,843
oligodendroglioma 23 | 2,850
adult high grade glioma 22 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
malignant mesothelioma 22 | 3,232
diabetes mellitus 21 | 1,728
Atherosclerosis 20 | 291
Breast cancer 20 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
Coronary artery disease 19 | 268
astrocytic glioma 19 | 2,597
Astrocytoma, Pilocytic 18 | 3,081
Obesity 18 | 678
ductal carcinoma in situ 18 | 1,745
interstitial cystitis 18 | 2,312
Lipid metabolism disorder 17 | 114
group 3 medulloblastoma 17 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
lung adenocarcinoma 16 | 2,716
pancreatic cancer 15 | 2,398
pituitary cancer 15 | 1,972
subependymal giant cell astrocytoma 15 | 2,287
spina bifida 14 | 1,074
active Crohn's disease 13 | 922
adrenocortical carcinoma 13 | 1,428
cutaneous lupus erythematosus 13 | 1,057
cystic fibrosis 13 | 1,696
non-small cell lung cancer 13 | 2,890
ulcerative colitis 13 | 1,819
Cardiovascular system disease 12 | 246
active ulcerative colitis 11 | 764
group 4 medulloblastoma 11 | 1,855
pediatric high grade glioma 11 | 1,064
Autosomal recessive predisposition 10 | 1,442
acute quadriplegic myopathy 10 | 1,158
primary pancreatic ductal adenocarcinoma 10 | 1,109
Alzheimer's disease 9 | 658
Kidney disease 9 | 430
Liver Cirrhosis, Experimental 9 | 769
nasopharyngeal carcinoma 9 | 1,058
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
Cholestasis 8 | 155
Hypertension 8 | 396
Pick disease 8 | 1,894
astrocytoma 8 | 1,146
non primary Sjogren syndrome sicca 8 | 891
Hypercholesterolemia, Familial 7 | 23
Hyperlipoproteinemia Type II 7 | 12
Liver disease 7 | 237
Schizophrenia 7 | 1,160
Waldenstrons macroglobulinemia 7 | 765
juvenile dermatomyositis 7 | 1,187
Cancer 6 | 2,499
Cerebrovascular disease 6 | 238
Dyslipidemias 6 | 27
Hypercholesterolemia 6 | 44
Melanoma 6 | 711
Vascular disease 6 | 319
breast carcinoma 6 | 1,638
chronic rhinosinusitis 6 | 512
colon cancer 6 | 1,478
primary Sjogren syndrome 6 | 735
progressive supranuclear palsy 6 | 676
Amyloidosis 5 | 67
Arcus Senilis 5 | 11
Cardiovascular Diseases 5 | 59
Coronary Disease 5 | 25
Coronary heart disease 5 | 16
Down syndrome 5 | 499
Fatty liver disease 5 | 103
Heart disease 5 | 306
Hepatomegaly 5 | 285
Hyperlipidemia 5 | 43
Hypertensive disease 5 | 292
Liver cancer 5 | 604
Multiple myeloma 5 | 1,332
Serum cholesterol raised 5 | 22
Simpson-Golabi-Behmel syndrome 5 | 19
Skin cancer 5 | 469
Splenomegaly 5 | 190
dermatomyositis 5 | 966
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
Rheumatoid arthritis 4 | 1,191
aldosterone-producing adenoma 4 | 665
nephrosclerosis 4 | 333
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Endocrine System 102 | 18,159
Digestive Tract 101 | 17,369
Female tissues 101 | 17,400
Liver and Pancreas 99 | 16,750
Male tissues 99 | 17,142
Skin and soft tissues 99 | 17,230
Urinary Tract 98 | 16,678
Blood and immune system 97 | 16,909
Nervous System 96 | 16,725
Respiratory system 93 | 16,393
Cardiovascular System 85 | 15,192

Target Family

Non-IDG 79 | 12,091
Transporter 19 | 473
Enzyme 3 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634

UniProt Keyword

Lipid transport 103 | 103
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MICOS complex subunit MIC26 APOO Tbio Non-IDG -1.25338 18.9 141
Cytoplasmic phosphatidylinositol transfer protein 1 PITPNC1 Tbio Non-IDG -0.74280 6.46 51
Vigilin HDLBP Tbio Non-IDG -2.01228 106.9 233
Major facilitator superfamily domain-containing protein 2B MFSD2B Tdark Non-IDG -0.40512 1.19 80
Phospholipid-transporting ATPase IA ATP8A1 Tbio Transporter -1.56158 35.5 43
Sigma non-opioid intracellular receptor 1 SIGMAR1 Tclin Non-IDG -2.28907 210.0 143
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.42853 26.4 88
Phospholipid-transporting ATPase IC ATP8B1 Tbio Transporter -2.47204 273.0 19
Anoctamin-3 ANO3 Tbio Non-IDG -1.18072 15.2 79
Sodium-dependent lysophosphatidylcholine symporter 1 MFSD2A Tbio Non-IDG -1.40175 26.3 73