Development Level

Tbio 59 | 11,651
Tchem 31 | 1,388
Tdark 11 | 6,593
Tclin 2 | 612

IMPC Phenotype

increased lean body mass 3 | 172
male infertility 3 | 123
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased circulating iron lev... 2 | 32
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
hydrometra 2 | 53
hypoactivity 2 | 132
preweaning lethality, complete... 2 | 979
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal gallbladder morpholog... 1 | 1
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
abnormal vocalization 1 | 21
decreased IgG3 level 1 | 1
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased brain size 1 | 4
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged gallbladder 1 | 2
improved glucose tolerance 1 | 79
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart weight 1 | 62
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
thrombocytopenia 1 | 56

Disease

Carcinoma 63 | 11,493
psoriasis 44 | 6,694
ovarian cancer 40 | 8,520
osteosarcoma 39 | 7,950
glioblastoma 32 | 5,792
lung cancer 32 | 4,740
medulloblastoma, large-cell 31 | 6,241
atypical teratoid / rhabdoid tumor 24 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
ependymoma 23 | 4,679
interstitial cystitis 23 | 2,312
lung carcinoma 23 | 2,843
adult high grade glioma 22 | 3,801
group 3 medulloblastoma 22 | 4,104
Astrocytoma, Pilocytic 21 | 3,081
diabetes mellitus 21 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
pancreatic cancer 19 | 2,398
Autosomal recessive predisposition 18 | 1,442
Breast cancer 18 | 3,578
invasive ductal carcinoma 18 | 2,951
malignant mesothelioma 18 | 3,232
lung adenocarcinoma 17 | 2,716
subependymal giant cell astrocytoma 17 | 2,287
non-small cell lung cancer 16 | 2,890
oligodendroglioma 16 | 2,850
Obesity 15 | 678
primitive neuroectodermal tumor 15 | 3,035
ulcerative colitis 15 | 1,819
Kidney cancer 12 | 2,613
group 4 medulloblastoma 12 | 1,855
Schizophrenia 11 | 1,160
breast carcinoma 11 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
pituitary cancer 11 | 1,972
Atherosclerosis 10 | 291
Cancer 10 | 2,499
Coronary artery disease 10 | 268
active Crohn's disease 10 | 922
astrocytic glioma 10 | 2,597
colon cancer 10 | 1,478
cutaneous lupus erythematosus 10 | 1,057
cystic fibrosis 10 | 1,696
ductal carcinoma in situ 10 | 1,745
active ulcerative colitis 9 | 764
adrenocortical carcinoma 9 | 1,428
tuberculosis 9 | 2,010
Lipid metabolism disorder 8 | 114
Rheumatoid arthritis 8 | 1,191
acute quadriplegic myopathy 8 | 1,158
nasopharyngeal carcinoma 8 | 1,058
Bipolar Disorder 7 | 666
Epilepsy 7 | 792
Liver Cirrhosis, Experimental 7 | 769
Neurodegenerative disease 7 | 414
esophageal adenocarcinoma 7 | 737
pediatric high grade glioma 7 | 1,064
primary pancreatic ductal adenocarcinoma 7 | 1,109
Dull intelligence 6 | 645
Hepatomegaly 6 | 285
Hyperreflexia 6 | 209
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Melanoma 6 | 711
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Muscle hypotonia 6 | 571
Poor school performance 6 | 645
Progressive disorder 6 | 142
Splenomegaly 6 | 190
astrocytoma 6 | 1,146
dermatomyositis 6 | 966
fibroadenoma 6 | 559
juvenile dermatomyositis 6 | 1,187
pancreatic carcinoma 6 | 562
primary Sjogren syndrome 6 | 735
Atopic dermatitis 5 | 952
Down syndrome 5 | 499
Hypertriglyceridemia result 5 | 37
Multiple myeloma 5 | 1,332
Pancreatitis 5 | 123
Pick disease 5 | 1,894
Polycystic ovary syndrome 5 | 360
Seizures 5 | 596
Steatorrhea 5 | 34
Toxic encephalopathy 5 | 141
hereditary spastic paraplegia 5 | 318
mucosa-associated lymphoid tissue lymphoma 5 | 484
non primary Sjogren syndrome sicca 5 | 891
non-small cell lung carcinoma 5 | 317
spina bifida 5 | 1,074
Cerebellar Ataxia 4 | 304
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Nystagmus 4 | 317
gastric cancer 4 | 459
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547

Tissue

Digestive Tract 101 | 17,369
Female tissues 101 | 17,400
Skin and soft tissues 100 | 17,230
Blood and immune system 99 | 16,909
Endocrine System 98 | 18,159
Urinary Tract 96 | 16,678
Male tissues 95 | 17,142
Liver and Pancreas 94 | 16,750
Respiratory system 91 | 16,393
Nervous System 90 | 16,725
Cardiovascular System 84 | 15,192

Target Family

Enzyme 93 | 4,145
Non-IDG 10 | 12,091

UniProt Keyword

Lipid degradation 103 | 103
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Endothelial lipase LIPG Tchem Enzyme -2.28530 192.2 712
Lipase member H LIPH Tbio Enzyme -1.36582 22.3 43
Sialidase-4 NEU4 Tchem Enzyme -1.39624 25.1 115
Sialidase-2 NEU2 Tbio Enzyme -2.12721 129.5 166
Phospholipase DDHD2 DDHD2 Tbio Enzyme -1.23833 16.6 49
Group IID secretory phospholipase A2 PLA2G2D Tchem Enzyme -2.16892 139.3 119
Phospholipase DDHD1 DDHD1 Tbio Enzyme -1.23443 15.3 31
Phospholipase B1, membrane-associated PLB1 Tdark Enzyme -1.65839 46.0 43
HRAS-like suppressor 3 PLA2G16 Tbio Non-IDG -1.96915 96.3 230