Development Level

Tclin 44 | 602
Tchem 25 | 1,890
Tbio 8 | 10,625
Tdark 2 | 7,003

Collection

Eligible Ion Channel Proteins 22 | 117

IMPC Term

decreased body weight 2 | 174
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
increased startle reflex 2 | 38
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating bilirubi... 1 | 14
decreased circulating glycerol... 1 | 19
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating choleste... 1 | 53
limb grasping 1 | 35
preweaning lethality, incomple... 1 | 260
small epididymis 1 | 3
thrombocytopenia 1 | 46

Disease

psoriasis 37 | 6,685
medulloblastoma, large-cell 35 | 6,234
Carcinoma 33 | 2,147
glioblastoma 32 | 5,572
Epilepsy 29 | 346
General anesthesia 27 | 53
atypical teratoid / rhabdoid tumor 27 | 4,369
Schizophrenia 25 | 501
pilocytic astrocytoma 24 | 3,086
oligodendroglioma 23 | 2,849
primitive neuroectodermal tumor 23 | 3,031
ependymoma 20 | 2,514
lung carcinoma 20 | 2,844
osteosarcoma 20 | 7,933
pediatric high grade glioma 20 | 2,712
Tonic-clonic epilepsy 18 | 47
Autistic Disorder 17 | 320
Local anesthesia 17 | 40
Nicotine dependence 17 | 53
astrocytic glioma 17 | 2,241
subependymal giant cell astrocytoma 15 | 2,287
Alcohol dependence 14 | 107
Lennox-Gastaut syndrome 14 | 34
medulloblastoma 14 | 1,524
ovarian cancer 14 | 8,484
pituitary cancer 14 | 1,972
Bipolar Disorder 13 | 266
Pick disease 13 | 1,893
Simple partial seizure 13 | 26
adult high grade glioma 12 | 2,148
lung cancer 12 | 4,466
Epilepsy characterized by intractable complex partial seizures 11 | 28
Irritable bowel syndrome 11 | 59
Migraine Prevention 11 | 22
Parkinson's disease 11 | 364
group 4 medulloblastoma 11 | 1,875
Alcoholism 9 | 14
Anxiety 9 | 24
Insomnia 9 | 20
Panic disorder 9 | 55
Sedation as Adjunct to Anesthesia 9 | 15
Breast cancer 8 | 3,094
Chemotherapy-induced nausea and vomiting 8 | 18
Intellectual disability 8 | 573
Spasticity 8 | 26
group 3 medulloblastoma 8 | 2,254
Arteriosclerotic Parkinsonism 7 | 8
Benzodiazepine Induced Sedation 7 | 8
Benzodiazepine Maintained Anesthesia 7 | 8
Benzodiazepine Toxicity 7 | 8
Extrapyramidal disease 7 | 8
Generalized anxiety disorder 7 | 29
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Major Depressive Disorder 7 | 106
Muscle relaxation, function 7 | 8
Parkinsonism 7 | 19
Postencephalitic parkinsonism 7 | 12
Seizures 7 | 95
Status Epilepticus 7 | 85
Substance Withdrawal Syndrome 7 | 52
Tetanus 7 | 66
Toxic encephalopathy 7 | 131
astrocytoma 7 | 1,493
atypical teratoid/rhabdoid tumor 7 | 1,095
interstitial cystitis 7 | 2,299
lung adenocarcinoma 7 | 2,713
posterior fossa group A ependymoma 7 | 1,511
ulcerative colitis 7 | 2,087
Alcohol withdrawal delirium 6 | 9
Alcohol withdrawal syndrome 6 | 9
Alzheimer's disease 6 | 644
Anxiety associated with Menopause 6 | 7
Frontal lobe epilepsy 6 | 8
Induce Anterograde Amnesia 6 | 9
Mixed anxiety and depressive disorder 6 | 10
Multiple pterygium syndrome 6 | 17
Partial Epilepsy Treatment Adjunct 6 | 16
Peptic ulcer 6 | 22
Pre-Op Apprehension 6 | 10
Preoperative Anxiety 6 | 9
Sedation 6 | 11
Sedation in Intubated Patients 6 | 8
Severe Insomnia 6 | 7
Severe anxiety (panic) 6 | 7
Smoking cessation assistance 6 | 8
cutaneous lupus erythematosus 6 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
non primary Sjogren syndrome sicca 6 | 840
Congenital myasthenic syndrome 5 | 28
Diabetic gastroparesis 5 | 7
Gastroesophageal reflux disease 5 | 37
Gastrointestinal Radiography Adjunct 5 | 11
Intubation of gastrointestinal tract 5 | 7
Neuropathy 5 | 210
Pellagra 5 | 25
Prevention of Post-Operative Nausea and Vomiting 5 | 14
sonic hedgehog group medulloblastoma 5 | 1,482

Tissue

Digestive Tract 79 | 18,473
Endocrine System 79 | 18,512
Female tissues 79 | 18,647
Nervous System 79 | 18,561
Urinary Tract 79 | 18,444
Liver and Pancreas 78 | 18,136
Skin and soft tissues 77 | 18,115
Respiratory system 75 | 17,484
Blood and immune system 74 | 17,995
Cardiovascular System 74 | 17,958
Male tissues 73 | 17,969

Target Family

Ion Channel 79 | 341

UniProt Keyword

Ligand-gated ion channel 79 | 79
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acetylcholine receptor subunit delta CHRND Tclin Ion Channel -1.23749 17.4 128
Glycine receptor subunit beta GLRB Tclin Ion Channel -1.15613 15.9 85
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.37968 2392.4 232
P2X purinoceptor 6 P2RX6 Tchem Ion Channel -1.46223 26.9 118
Acetylcholine receptor subunit beta CHRNB1 Tclin Ion Channel -1.24555 17.5 166
Neuronal acetylcholine receptor subunit alpha-7 CHRFAM7A Tchem Ion Channel -1.90534 84.1 211
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.59352 37.2 293
Glutamate receptor ionotropic, delta-2 GRID2 Tbio Ion Channel -2.02027 111.0 70
Glutamate receptor ionotropic, delta-1 GRID1 Tbio Ion Channel -1.01738 9.38 156