Development Level

Tchem 2 | 1,598
Tbio 1 | 11,445

IMPC Phenotype

abnormal lens morphology 1 | 81
cataract 1 | 92
increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499

Disease

Breast cancer 3 | 3,578
Cancer 3 | 2,499
Carcinoma 3 | 11,493
DOID:2627 3 | 94
Li-Fraumeni syndrome 3 | 13
Lymphoma 3 | 81
Stomach cancer 3 | 30
lung cancer 3 | 4,740
ovarian cancer 3 | 8,520
Abnormality of metabolism/homeostasis 2 | 134
Actinic keratosis 2 | 21
Adenoma 2 | 167
Barrett's esophagus 2 | 182
Biliary tract cancer 2 | 19
Breast Neoplasms 2 | 445
Cervix uteri carcinoma in situ 2 | 16
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
ENSP00000256078 2 | 30
Encephalopathy, progressive 2 | 6
Esophageal carcinoma 2 | 16
Gastrointestinal stromal tumor 2 | 62
Glaucoma 2 | 239
Glioma 2 | 74
Head and neck squamous cell carcinoma 2 | 11
Hereditary Breast and Ovarian Cancer Syndrome 2 | 14
Immune system cancer 2 | 140
Increased risk of pancreatic cancer 2 | 9
Li-Fraumeni syndrome 2 2 | 2
Liver cancer 2 | 604
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
Malignant neoplasm of pancreas 2 | 9
Malignant neoplasm of prostate 2 | 11
Malignant neoplasm of skin 2 | 15
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Mouth Neoplasms 2 | 55
Nervous System Neoplasms 2 | 8
Nijmegen breakage syndrome 2 | 24
Osteogenic Sarcoma 2 | 6
Pancreatic Neoplasm 2 | 85
Papilloma 2 | 44
Progressive brain disease 2 | 6
Prostatic Neoplasms 2 | 495
Renal Cell Carcinoma 2 | 214
Retinal Neoplasms 2 | 3
Retinoblastoma 2 | 19
Sarcoma 2 | 62
Skin Neoplasms 2 | 69
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Tumors of Adrenal Cortex 2 | 3
Upper respiratory tract disease 2 | 15
Vascular disease 2 | 319
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035
Adenocarcinoma Of Esophagus 1 | 14
Adenocarcinoma of lung (disorder) 1 | 60
Adenocarcinoma, Clear Cell 1 | 2
Adrenal Gland Neoplasms 1 | 11
Ameloblastoma 1 | 24
Balkan Nephropathy 1 | 6
Carcinoma, Small Cell 1 | 9
Carotid Artery Diseases 1 | 11
Central Nervous System Neoplasms 1 | 2
Choroid Plexus Papilloma 1 | 10
Chronic Obstructive Airway Disease 1 | 37
Demyelinating Diseases 1 | 7
Genitourinary Neoplasms 1 | 3
Hemangiosarcoma 1 | 18
In situ carcinoma 1 | 3
Intestinal benign neoplasm 1 | 12
Ischemia 1 | 28
Liver Diseases, Parasitic 1 | 9
Malignant tumor of colon 1 | 19
Micronodular cirrhosis 1 | 12
Nausea 1 | 20
Neurilemmoma 1 | 23
Papilledema 1 | 11
Pathological accumulation of air in tissues 1 | 10
Penile Neoplasms 1 | 4
Peutz-Jeghers syndrome 1 | 21
Polyploidy 1 | 4
Skin benign neoplasm 1 | 6
Small cell carcinoma of lung 1 | 45
T-Cell Lymphoma 1 | 13
Thymoma 1 | 16
Transitional cell carcinoma of bladder 1 | 17
Urologic Neoplasms 1 | 8
Vulvar Lichen Sclerosus 1 | 2
gallbladder neoplasm 1 | 10

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 1 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

UniProt Keyword

Li-Fraumeni syndrome 3 | 3
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -3.00304 978.7 1374
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298