Development Level

Tbio 157 | 11,651
Tdark 136 | 6,593
Tchem 11 | 1,388
Tclin 8 | 612

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Complete... 2 | 25
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 13 | 979
decreased vertical activity 8 | 208
abnormal behavior 7 | 298
preweaning lethality, incomple... 5 | 499
increased neutrophil cell numb... 4 | 46
male infertility 4 | 123
prenatal lethality prior to he... 4 | 87
decreased body weight 3 | 161
decreased lean body mass 3 | 135
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased circulating calcium ... 3 | 34
increased mean corpuscular vol... 3 | 92
small testis 3 | 58
small thymus 3 | 16
thrombocytopenia 3 | 56
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal lung morphology 2 | 26
abnormal maxilla morphology 2 | 17
abnormal rib morphology 2 | 10
abnormal seminal vesicle morph... 2 | 114
abnormal tail morphology 2 | 25
abnormal testis morphology 2 | 43
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased body length 2 | 32
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
small spleen 2 | 19
small superior vagus ganglion 2 | 74
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal eyelid morphology 1 | 7
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
absent teeth 1 | 3
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased red blood cell distr... 1 | 41
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 38
increased eosinophil cell numb... 1 | 11
increased heart rate 1 | 23
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
limb grasping 1 | 41
polycystic kidney 1 | 15
prenatal lethality 1 | 28
vertebral fusion 1 | 23

Disease

Carcinoma 210 | 11,493
psoriasis 114 | 6,694
osteosarcoma 110 | 7,950
ovarian cancer 105 | 8,520
glioblastoma 101 | 5,792
medulloblastoma, large-cell 100 | 6,241
ependymoma 87 | 4,679
atypical teratoid / rhabdoid tumor 82 | 5,112
adult high grade glioma 73 | 3,801
lung cancer 71 | 4,740
Kidney cancer 62 | 2,613
group 3 medulloblastoma 60 | 4,104
Astrocytoma, Pilocytic 54 | 3,081
Breast cancer 53 | 3,578
lung carcinoma 49 | 2,843
astrocytic glioma 47 | 2,597
invasive ductal carcinoma 47 | 2,951
malignant mesothelioma 44 | 3,232
non-small cell lung cancer 44 | 2,890
oligodendroglioma 44 | 2,850
lung adenocarcinoma 43 | 2,716
pituitary cancer 42 | 1,972
primitive neuroectodermal tumor 42 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
pancreatic cancer 38 | 2,398
interstitial cystitis 37 | 2,312
group 4 medulloblastoma 33 | 1,855
ulcerative colitis 31 | 1,819
subependymal giant cell astrocytoma 29 | 2,287
cystic fibrosis 28 | 1,696
ductal carcinoma in situ 28 | 1,745
tuberculosis 28 | 2,010
Cancer 27 | 2,499
adrenocortical carcinoma 27 | 1,428
breast carcinoma 27 | 1,638
Pick disease 23 | 1,894
colon cancer 23 | 1,478
facioscapulohumeral dystrophy 23 | 288
Atopic dermatitis 21 | 952
primary pancreatic ductal adenocarcinoma 19 | 1,109
Melanoma 18 | 711
Schizophrenia 17 | 1,160
medulloblastoma 17 | 720
Duchenne muscular dystrophy 16 | 601
Skin cancer 16 | 469
astrocytoma 16 | 1,146
juvenile dermatomyositis 16 | 1,187
Autosomal recessive predisposition 15 | 1,442
cutaneous lupus erythematosus 15 | 1,057
nasopharyngeal carcinoma 15 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Rheumatoid arthritis 14 | 1,191
diabetes mellitus 14 | 1,728
sonic hedgehog group medulloblastoma 14 | 467
Liver cancer 13 | 604
fibroadenoma 12 | 559
gastric carcinoma 12 | 807
non primary Sjogren syndrome sicca 12 | 891
posterior fossa group A ependymoma 12 | 468
spina bifida 12 | 1,074
Multiple Sclerosis 11 | 540
aldosterone-producing adenoma 11 | 665
pediatric high grade glioma 11 | 1,064
Alzheimer's disease 10 | 658
Bipolar Disorder 10 | 666
esophageal adenocarcinoma 10 | 737
limb girdle muscular dystrophy 2A 10 | 213
posterior fossa group B ependymoma 10 | 416
primary Sjogren syndrome 10 | 735
Liver Cirrhosis, Experimental 9 | 769
Multiple myeloma 9 | 1,332
active Crohn's disease 9 | 922
acute quadriplegic myopathy 9 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
dermatomyositis 9 | 966
Asthma 8 | 385
Down syndrome 8 | 499
Waldenstrons macroglobulinemia 8 | 765
chronic rhinosinusitis 8 | 512
gastric cancer 8 | 459
mucosa-associated lymphoid tissue lymphoma 8 | 484
pancreatic carcinoma 8 | 562
progressive supranuclear palsy 8 | 676
Arthritis 7 | 290
Colorectal Neoplasms 7 | 243
Endometriosis 7 | 540
Influenza 7 | 142
Kidney disease 7 | 430
Male infertility 7 | 206
Myopia 7 | 176
Obesity 7 | 678
Polycystic ovary syndrome 7 | 360
active ulcerative colitis 7 | 764
Chronic obstructive pulmonary disease 6 | 184
Epilepsy 6 | 792
Intellectual disability 6 | 1,016
hepatocellular carcinoma 6 | 547
non diabetic and post-ischemic heart failure 6 | 200

Tissue

Endocrine System 288 | 18,159
Female tissues 269 | 17,400
Digestive Tract 268 | 17,369
Male tissues 264 | 17,142
Blood and immune system 259 | 16,909
Nervous System 259 | 16,725
Skin and soft tissues 259 | 17,230
Liver and Pancreas 252 | 16,750
Respiratory system 252 | 16,393
Urinary Tract 249 | 16,678
Cardiovascular System 222 | 15,192

Target Family

Non-IDG 276 | 12,091
Enzyme 15 | 4,145
GPCR 10 | 408
Kinase 5 | 634
Ion Channel 4 | 344
Epigenetic 2 | 242

UniProt Keyword

Leucine-rich repeat 312 | 312
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leucine-rich repeat-containing protein 72 LRRC72 Tdark Non-IDG 0.00000 39
Protein zyg-11 homolog B ZYG11B Tdark Non-IDG -0.49136 2.50 52
Protein phosphatase 1 regulatory subunit 29 ELFN2 Tdark Enzyme 0.06 0.68 51
Immunoglobulin superfamily containing leucine-rich repeat protein 2 ISLR2 Tbio Non-IDG -1.71209 49.0 64
Leucine-rich repeats and immunoglobulin-like domains protein 3 LRIG3 Tbio Non-IDG -1.14921 15.6 94
F-box/LRR-repeat protein 7 FBXL7 Tbio Non-IDG -0.80631 6.84 53
Leucine-rich repeat and fibronectin type-III domain-containing protein 2 LRFN2 Tbio Non-IDG -0.81315 6.12 97
Osteomodulin OMD Tbio Non-IDG -2.36749 234.5 121
F-box/LRR-repeat protein 3 FBXL3 Tbio Non-IDG -0.99438 10.2 174
F-box/LRR-repeat protein 21 FBXL21 Tdark Non-IDG 0.00000 0