Development Level

Tdark 144 | 7,003
Tbio 142 | 10,625
Tchem 17 | 1,890
Tclin 7 | 602

Collection

Eligible Ion Channel Proteins 3 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
abnormal behavior 6 | 226
decreased body weight 3 | 174
male infertility 3 | 62
preweaning lethality, incomple... 3 | 260
abnormal maxilla morphology 2 | 16
abnormal spinal cord morpholog... 2 | 8
abnormal tail morphology 2 | 17
decreased eosinophil cell numb... 2 | 41
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased lumbar vertebrae num... 2 | 62
herniated abdominal wall 2 | 4
improved glucose tolerance 2 | 56
increased circulating calcium ... 2 | 32
increased hemoglobin content 2 | 45
increased monocyte cell number 2 | 27
increased or absent threshold ... 2 | 128
increased rib number 2 | 41
prenatal lethality prior to he... 2 | 64
small testis 2 | 37
small thymus 2 | 11
thrombocytopenia 2 | 46
abnormal QRS complex 1 | 25
abnormal brain morphology 1 | 6
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eyelid morphology 1 | 6
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 24
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal mandible morphology 1 | 2
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 11
abnormal pericardium morpholog... 1 | 11
abnormal placenta size 1 | 10
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal sacral vertebrae morp... 1 | 5
abnormal snout morphology 1 | 18
abnormal testis morphology 1 | 30
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vocalization 1 | 21
absent teeth 1 | 4
craniofacial phenotype 1 | 9
decreased IgE level 1 | 3
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased brain size 1 | 4
decreased cardiac muscle contr... 1 | 5
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased heart rate 1 | 10
decreased kidney weight 1 | 7
decreased mean platelet volume 1 | 12
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hydroencephaly 1 | 6
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased erythrocyte cell num... 1 | 26
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased thoracic vertebrae n... 1 | 8
lethargy 1 | 5
limb grasping 1 | 35
narrow eye opening 1 | 15
no abnormal phenotype detected 1 | 3
pale yolk sac 1 | 12
polycystic kidney 1 | 9
polydactyly 1 | 22
prenatal lethality 1 | 16
short tibia 1 | 82
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
urinary bladder obstruction 1 | 2
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

psoriasis 114 | 6,685
osteosarcoma 110 | 7,933
ovarian cancer 104 | 8,484
medulloblastoma, large-cell 100 | 6,234
glioblastoma 95 | 5,572
atypical teratoid / rhabdoid tumor 74 | 4,369
Carcinoma 61 | 2,147
lung cancer 61 | 4,466
pilocytic astrocytoma 54 | 3,086
lung carcinoma 49 | 2,844
invasive ductal carcinoma 47 | 2,950
malignant mesothelioma 44 | 3,162
oligodendroglioma 44 | 2,849
adult high grade glioma 43 | 2,148
lung adenocarcinoma 43 | 2,713
astrocytic glioma 42 | 2,241
pituitary cancer 42 | 1,972
primitive neuroectodermal tumor 42 | 3,031
pediatric high grade glioma 41 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,289
non-small cell lung cancer 40 | 2,798
Breast cancer 39 | 3,094
pancreatic cancer 38 | 2,300
interstitial cystitis 37 | 2,299
posterior fossa group A ependymoma 37 | 1,511
sonic hedgehog group medulloblastoma 37 | 1,482
ependymoma 36 | 2,514
posterior fossa group B ependymoma 36 | 1,530
ulcerative colitis 34 | 2,087
group 3 medulloblastoma 30 | 2,254
group 4 medulloblastoma 29 | 1,875
subependymal giant cell astrocytoma 29 | 2,287
cystic fibrosis 28 | 1,665
ductal carcinoma in situ 28 | 1,745
medulloblastoma 28 | 1,524
adrenocortical carcinoma 27 | 1,427
breast carcinoma 27 | 1,614
Cancer 24 | 2,346
Pick disease 23 | 1,893
colon cancer 23 | 1,475
facioscapulohumeral dystrophy 23 | 286
tuberculosis 23 | 1,557
Atopic dermatitis 21 | 944
astrocytoma 21 | 1,493
primary pancreatic ductal adenocarcinoma 20 | 1,271
Duchenne muscular dystrophy 16 | 602
juvenile dermatomyositis 16 | 1,189
cutaneous lupus erythematosus 15 | 1,056
nasopharyngeal carcinoma 15 | 1,056
Rheumatoid Arthritis 14 | 1,160
diabetes mellitus 14 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
atypical teratoid/rhabdoid tumor 12 | 1,095
fibroadenoma 12 | 557
gastric carcinoma 12 | 832
non primary Sjogren syndrome sicca 12 | 840
spina bifida 12 | 1,064
aldosterone-producing adenoma 11 | 664
non-small cell lung carcinoma 11 | 413
Obesity 10 | 616
esophageal adenocarcinoma 10 | 737
primary Sjogren syndrome 10 | 789
Alzheimer's disease 9 | 644
Asthma 9 | 349
IGA Glomerulonephritis 9 | 454
Multiple Sclerosis 9 | 498
Multiple myeloma 9 | 1,327
active Crohn's disease 9 | 918
acute quadriplegic myopathy 9 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
dermatomyositis 9 | 933
limb girdle muscular dystrophy 2A 9 | 156
Down syndrome 8 | 548
Influenza 8 | 142
Waldenstrons macroglobulinemia 8 | 765
chronic rhinosinusitis 8 | 512
gastric cancer 8 | 430
glioblastoma multiforme 8 | 347
mucosa-associated lymphoid tissue lymphoma 8 | 480
pancreatic carcinoma 8 | 567
progressive supranuclear palsy 8 | 674
Endometriosis 7 | 535
Polycystic Ovary Syndrome 7 | 332
Schizophrenia 7 | 501
Atherosclerosis 6 | 275
Bipolar Disorder 6 | 266
Kidney disease 6 | 396
Male infertility 6 | 170
Myopia 6 | 99
Parkinson's disease 6 | 364
hepatocellular carcinoma 6 | 532
non diabetic and post-ischemic heart failure 6 | 200
Arthritis 5 | 248
Cerebrovascular disease 5 | 231
Chronic obstructive pulmonary disease 5 | 146
Heart disease 5 | 279
head and neck cancer 5 | 270
inflammatory breast cancer 5 | 404

Tissue

Female tissues 296 | 18,647
Digestive Tract 295 | 18,473
Endocrine System 293 | 18,512
Urinary Tract 293 | 18,444
Nervous System 290 | 18,561
Liver and Pancreas 289 | 18,136
Blood and immune system 288 | 17,995
Skin and soft tissues 286 | 18,115
Male tissues 285 | 17,969
Cardiovascular System 283 | 17,958
Respiratory system 275 | 17,484

Target Family

Non-IDG 274 | 11,971
Enzyme 15 | 4,146
GPCR 10 | 406
Kinase 5 | 634
Ion Channel 4 | 341
Epigenetic 2 | 242

UniProt Keyword

Leucine-rich repeat 310 | 310
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Leucine-rich repeat-containing protein 74B LRRC74B Tdark Non-IDG 0.00000 1.00 17
Protein C21orf2 C21orf2 Tbio Non-IDG -1.66840 37.4 95
Ribonuclease inhibitor RNH1 Tbio Enzyme -2.79304 640.5 234
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
SLIT and NTRK-like protein 5 SLITRK5 Tbio Non-IDG -0.75000 6.92 84
Adhesion G protein-coupled receptor A3 ADGRA3 Tbio GPCR -0.92696 10.7 107
Leucine-rich alpha-2-glycoprotein LRG1 Tbio Non-IDG -2.05099 124.2 190
F-box/LRR-repeat protein 13 FBXL13 Tdark Non-IDG -0.47349 2.81 66
Platelet glycoprotein IX GP9 Tbio Non-IDG -2.22681 159.1 295