Development Level

Tbio 26 | 11,445
Tdark 4 | 6,588

IMPC Phenotype

abnormal skin morphology 2 | 50
preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent testes 1 | 6
decreased body weight 1 | 161
decreased circulating choleste... 1 | 93
decreased grip strength 1 | 116
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
thrombocytopenia 1 | 56

Disease

Carcinoma 29 | 11,493
Kidney cancer 24 | 2,613
glioblastoma 19 | 5,792
Breast cancer 17 | 3,578
ovarian cancer 17 | 8,520
lung cancer 16 | 4,740
psoriasis 15 | 6,694
ependymoma 13 | 4,679
atypical teratoid / rhabdoid tumor 12 | 5,112
malignant mesothelioma 12 | 3,232
medulloblastoma, large-cell 12 | 6,241
pancreatic cancer 12 | 2,398
invasive ductal carcinoma 11 | 2,951
lung carcinoma 11 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Autosomal recessive predisposition 10 | 1,442
Astrocytoma, Pilocytic 9 | 3,081
Liver cancer 9 | 604
osteosarcoma 9 | 7,950
adult high grade glioma 8 | 3,801
cystic fibrosis 8 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Skin cancer 7 | 469
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
non-small cell lung cancer 7 | 2,890
subependymal giant cell astrocytoma 7 | 2,287
Endometrial cancer 6 | 311
Intellectual disability 6 | 1,016
Melanoma 6 | 711
Myopia 6 | 176
active ulcerative colitis 6 | 764
lung adenocarcinoma 6 | 2,716
oligodendroglioma 6 | 2,850
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Duchenne muscular dystrophy 5 | 601
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Schizophrenia 5 | 1,160
astrocytic glioma 5 | 2,597
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pediatric high grade glioma 5 | 1,064
primary pancreatic ductal adenocarcinoma 5 | 1,109
Flexion contracture of proximal interphalangeal joint 4 | 75
Pierson syndrome 4 | 13
Prenatal onset 4 | 139
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
juvenile dermatomyositis 4 | 1,187
sonic hedgehog group medulloblastoma 4 | 467
tuberculosis 4 | 2,010
Abnormal blistering of the skin 3 | 54
Abnormal pigmentation 3 | 25
Age related macular degeneration 1 3 | 4
Anemia 3 | 365
Bipolar Disorder 3 | 666
Blister of skin 3 | 54
Broad flat nasal bridge 3 | 236
Cardiovascular system disease 3 | 246
DOID:2627 3 | 94
Death in early childhood 3 | 82
Death in infancy 3 | 82
Dehydration 3 | 40
Dental Enamel Hypoplasia 3 | 43
Dental caries 3 | 164
Dyspnea 3 | 76
Dystrophia unguium 3 | 53
Epidermolysis bullosa 3 | 21
Epilepsy 3 | 792
Esophageal Stenosis 3 | 15
Failure to gain weight 3 | 365
Hemoglobin low 3 | 124
Hoarseness 3 | 31
Hypodontia 3 | 81
Junctional epidermolysis bullosa 3 | 7
Myopathy 3 | 185
Nail dysplasia 3 | 52
Nasal bridge wide 3 | 236
Pediatric failure to thrive 3 | 365
Pyloric Stenosis 3 | 47
Rotting teeth 3 | 73
Seizures 3 | 596
Skin bulla 3 | 54
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
fibroadenoma 3 | 559
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
spina bifida 3 | 1,074

Tissue

Endocrine System 30 | 18,159
Blood and immune system 29 | 16,909
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Digestive Tract 28 | 17,369
Respiratory system 28 | 16,393
Cardiovascular System 25 | 15,192

Target Family

Non-IDG 26 | 12,091
GPCR 3 | 408
Enzyme 1 | 4,145

UniProt Keyword

Laminin EGF-like domain 30 | 30
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stabilin-1 STAB1 Tbio Non-IDG -1.61013 45.4 107
Netrin-5 NTN5 Tdark Non-IDG 0.09 1.55 32
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Laminin subunit beta-4 LAMB4 Tbio Non-IDG -0.78478 6.19 13
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.47924 34.4 115
Cadherin EGF LAG seven-pass G-type receptor 3 CELSR3 Tbio GPCR -1.38072 25.3 190
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Attractin ATRN Tbio Non-IDG -2.61000 386.6 172
Usherin USH2A Tbio Non-IDG -2.45871 284.8 38
Multiple epidermal growth factor-like domains protein 9 MEGF9 Tdark Non-IDG -0.17276 1.32 103