Development Level

Tbio 60 | 11,445
Tdark 9 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
hypoactivity 2 | 132
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal locomotor activation 1 | 16
abnormal retina morphology 1 | 71
absent teeth 1 | 3
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
enlarged pancreas 1 | 2
eye hemorrhage 1 | 1
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9
increased lean body mass 1 | 172
long tibia 1 | 25
short tibia 1 | 97

Disease

Carcinoma 40 | 11,493
ovarian cancer 39 | 8,520
glioblastoma 37 | 5,792
osteosarcoma 32 | 7,950
atypical teratoid / rhabdoid tumor 30 | 5,112
medulloblastoma, large-cell 30 | 6,241
psoriasis 30 | 6,694
ependymoma 29 | 4,679
Astrocytoma, Pilocytic 28 | 3,081
lung cancer 28 | 4,740
adult high grade glioma 26 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
non-small cell lung cancer 23 | 2,890
pancreatic cancer 22 | 2,398
primitive neuroectodermal tumor 22 | 3,035
malignant mesothelioma 20 | 3,232
Breast cancer 19 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
lung adenocarcinoma 19 | 2,716
lung carcinoma 18 | 2,843
group 3 medulloblastoma 17 | 4,104
invasive ductal carcinoma 17 | 2,951
oligodendroglioma 17 | 2,850
breast carcinoma 15 | 1,638
subependymal giant cell astrocytoma 15 | 2,287
group 4 medulloblastoma 14 | 1,855
astrocytic glioma 13 | 2,597
cystic fibrosis 13 | 1,696
spina bifida 13 | 1,074
pituitary cancer 12 | 1,972
primary pancreatic ductal adenocarcinoma 12 | 1,109
acute quadriplegic myopathy 11 | 1,158
gastric carcinoma 11 | 807
adrenocortical carcinoma 10 | 1,428
astrocytoma 10 | 1,146
colon cancer 10 | 1,478
dermatomyositis 10 | 966
esophageal adenocarcinoma 10 | 737
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Cancer 9 | 2,499
Pick disease 9 | 1,894
ductal carcinoma in situ 9 | 1,745
interstitial cystitis 9 | 2,312
tuberculosis 9 | 2,010
active Crohn's disease 8 | 922
nasopharyngeal carcinoma 8 | 1,058
pediatric high grade glioma 8 | 1,064
ulcerative colitis 8 | 1,819
Liver Cirrhosis, Experimental 7 | 769
Amyotrophic lateral sclerosis 6 | 451
Polycystic ovary syndrome 6 | 360
Rheumatoid arthritis 6 | 1,191
cutaneous lupus erythematosus 6 | 1,057
diabetes mellitus 6 | 1,728
interstitial lung disease 6 | 298
juvenile dermatomyositis 6 | 1,187
Bipolar Disorder 5 | 666
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Schizophrenia 5 | 1,160
active ulcerative colitis 5 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
pancreatic carcinoma 5 | 562
sonic hedgehog group medulloblastoma 5 | 467
Acquired metabolic disease 4 | 336
Kidney cancer 4 | 2,613
Short stature 4 | 531
chronic rhinosinusitis 4 | 512
fibroadenoma 4 | 559
medulloblastoma 4 | 720
progressive supranuclear palsy 4 | 676
Atopic dermatitis 3 | 952
COPD 3 | 118
Cardiomyopathy, Dilated 3 | 83
Chronic Lymphocytic Leukemia 3 | 262
Creatine phosphokinase serum increased 3 | 110
Elevated creatine kinase 3 | 110
Emery-Dreifuss muscular dystrophy 3 | 23
Familial isolated dilated cardiomyopathy 3 | 41
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
LEFT VENTRICULAR NONCOMPACTION 10 3 | 40
LEFT VENTRICULAR NONCOMPACTION 8 3 | 40
Parkinson's disease 3 | 392
Prostate cancer 3 | 175
Sensorineural Hearing Loss (disorder) 3 | 284
Substance-Related Disorders 3 | 115
Waldenstrons macroglobulinemia 3 | 765
X-linked cerebral adrenoleukodystrophy 3 | 116
chronic kidney disease 3 | 90
gastric cancer 3 | 459
head and neck cancer 3 | 271
hereditary spastic paraplegia 3 | 318
non diabetic and post-ischemic heart failure 3 | 200
non primary Sjogren syndrome sicca 3 | 891
urothelial carcinoma 3 | 318
Curvature of spine 2 | 282
Epilepsy 2 | 792
Umbilical hernia 2 | 93

Tissue

Endocrine System 69 | 18,159
Digestive Tract 68 | 17,369
Female tissues 66 | 17,400
Liver and Pancreas 66 | 16,750
Urinary Tract 66 | 16,678
Nervous System 65 | 16,725
Blood and immune system 64 | 16,909
Male tissues 64 | 17,142
Skin and soft tissues 64 | 17,230
Cardiovascular System 62 | 15,192
Respiratory system 60 | 16,393

Target Family

Non-IDG 54 | 12,091
Transcription Factor 12 | 1,400
Enzyme 3 | 4,145
Kinase 2 | 634

UniProt Keyword

LIM domain 71 | 71
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LIM domain only protein 7 LMO7 Tbio Non-IDG -1.24771 19.7 80
Four and a half LIM domains protein 1 FHL1 Tbio Non-IDG -2.46134 291.4 312
LIM/homeobox protein Lhx8 LHX8 Tbio Transcription Factor -1.58436 40.6 163
LIM and SH3 domain protein 1 LASP1 Tbio Non-IDG -1.87137 77.5 299
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.26880 23.6 187
Nebulin-related-anchoring protein NRAP Tbio Non-IDG -0.50644 3.42 54
Lipoma-preferred partner LPP Tbio Non-IDG -2.77949 582.6 164
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -2.00418 105.2 236
PDZ and LIM domain protein 4 PDLIM4 Tbio Non-IDG -2.02708 99.1 145
LIM/homeobox protein Lhx2 LHX2 Tbio Transcription Factor -1.93103 91.8 221