Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal snout morphology 1 | 23
decreased circulating unsatura... 1 | 2
decreased food intake 1 | 13
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41

Disease

Carcinoma 6 | 11,493
invasive ductal carcinoma 6 | 2,951
Breast cancer 5 | 3,578
lung cancer 5 | 4,740
osteosarcoma 5 | 7,950
Atherosclerosis 4 | 291
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
ovarian cancer 4 | 8,520
pancreatic cancer 4 | 2,398
psoriasis 4 | 6,694
Coronary artery disease 3 | 268
Kidney cancer 3 | 2,613
Lipid metabolism disorder 3 | 114
Melanoma 3 | 711
Skin cancer 3 | 469
atypical teratoid / rhabdoid tumor 3 | 5,112
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group A ependymoma 3 | 468
Alzheimer's disease 2 | 658
Angina Pectoris 2 | 32
Arcus Senilis 2 | 11
Arcus juvenilis 2 | 5
Atherosclerosis of aorta 2 | 5
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cardiovascular system disease 2 | 246
Cerebral artery atherosclerosis 2 | 3
Coronary Arteriosclerosis 2 | 6
Coronary Disease 2 | 25
Coronary artery disease, premature 2 | 6
Coronary heart disease 2 | 16
Dyslipidemias 2 | 27
Dyspnea 2 | 76
Eyelid Xanthoma 2 | 5
Familial hypercholesterolemia - homozygous 2 | 7
Fatty Liver 2 | 70
Fatty liver disease 2 | 103
Heart murmur 2 | 5
Hypercholesterolemia 2 | 44
Hypercholesterolemia, Familial 2 | 23
Hyperlipidemia 2 | 43
Hyperlipidemias 2 | 17
Hyperlipoproteinemia Type II 2 | 12
Hyperlipoproteinemia Type IIa 2 | 11
Hypertensive disease 2 | 292
Impaired left ventricular function 2 | 16
Increase in blood pressure 2 | 119
Internal carotid artery abnormalities 2 | 3
Left-Sided Heart Failure 2 | 16
Low density lipoprotein increased 2 | 8
Myocardial Infarction 2 | 151
Myocardial steatosis 2 | 3
Obesity 2 | 678
Peripheral arterial stenosis 2 | 4
Plaque build-up in arteries supplying blood to heart 2 | 6
Precocious atherosclerosis 2 | 4
Premature arteriosclerosis 2 | 5
Premature hardening of arteries 2 | 5
Premature plaque build-up in arteries 2 | 4
Renal Artery Stenosis 2 | 9
Serum cholesterol raised 2 | 22
Steatohepatitis 2 | 44
Sudden Cardiac Death 2 | 29
Vascular disease 2 | 319
Xanthelasma of periocular region 2 | 5
Xanthoma 2 | 5
Xanthoma of periocular region 2 | 5
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Acanthocytosis 1 | 7
Animal Mammary Neoplasms 1 | 136
Barrett's esophagus 1 | 182
Chemical and Drug Induced Liver Injury 1 | 195
DOID:2627 1 | 94
Decreased to absent deep tendon reflexes 1 | 42
Drug Eruptions 1 | 18
Gaucher disease type 1 1 | 180
Hyperinsulinism 1 | 133
Hypobetalipoproteinemias 1 | 5
Large intestine cancer 1 | 126
Liver disease 1 | 237
Low density lipoprotein decreased 1 | 5
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Metabolic syndrome X 1 | 52
Non-alcoholic Fatty Liver Disease 1 | 42
Pancreatitis 1 | 123
Somatic mutation 1 | 61
Steatorrhea 1 | 34
inflammatory breast cancer 1 | 286
sarcoidosis 1 | 370

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192
Nervous System 8 | 16,725
Skin and soft tissues 8 | 17,230
Respiratory system 7 | 16,393

Target Family

Non-IDG 9 | 12,091

UniProt Keyword

LDL 9 | 9
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MICOS complex subunit MIC26 APOO Tbio Non-IDG -1.25338 18.9 141
Apolipoprotein B receptor APOBR Tbio Non-IDG -1.00933 12.4 135
Apolipoprotein B-100 APOB Tchem Non-IDG -4.00022 10024.1 856
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.06808 938.9 585
Lipolysis-stimulated lipoprotein receptor LSR Tbio Non-IDG -1.92670 81.8 89
Apolipoprotein F APOF Tbio Non-IDG -1.45156 33.3 232
Apolipoprotein C-II APOC2 Tbio Non-IDG -2.51086 342.7 22
Sortilin-related receptor SORL1 Tbio Non-IDG -2.22799 188.4 169
Macrophage scavenger receptor types I and II MSR1 Tbio Non-IDG -2.17658 149.3 654