Development Level

Tbio 19 | 11,445
Tdark 18 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

abnormal bone structure 2 | 187
preweaning lethality, incomple... 2 | 499
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal skin morphology 1 | 50
abnormal vibrissa morphology 1 | 25
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
male infertility 1 | 123
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small kidney 1 | 16

Disease

psoriasis 24 | 6,694
Carcinoma 12 | 11,493
diabetes mellitus 11 | 1,728
esophageal adenocarcinoma 9 | 737
lung cancer 8 | 4,740
ovarian cancer 7 | 8,520
Atopic dermatitis 6 | 952
cystic fibrosis 6 | 1,696
nasopharyngeal carcinoma 6 | 1,058
non-small cell lung cancer 6 | 2,890
osteosarcoma 6 | 7,950
Kidney cancer 5 | 2,613
medulloblastoma, large-cell 5 | 6,241
Epidermolytic hyperkeratosis 4 | 14
Ichthyosis 4 | 56
Ichthyosis vulgaris 4 | 11
cutaneous lupus erythematosus 4 | 1,057
interstitial cystitis 4 | 2,312
spina bifida 4 | 1,074
Breast cancer 3 | 3,578
Carcinoma, Squamous Cell 3 | 110
Congenital ichthyosiform erythroderma 3 | 28
Irritant dermatitis 3 | 9
Squamous cell carcinoma 3 | 129
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
Alopecia 2 | 115
Asthma 2 | 385
Bullous pemphigoid 2 | 18
Congenital Nonbullous Ichthyosiform Erythroderma 2 | 16
DOID:2627 2 | 94
Dry eye syndrome 2 | 18
Endometrial cancer 2 | 311
Hyperkeratosis 2 | 50
Keratosis 2 | 37
Liver cancer 2 | 604
Melanoma 2 | 711
Palmoplantar keratosis 2 | 74
Pemphigus 2 | 23
Pick disease 2 | 1,894
Psoriatic arthritis 2 | 86
Skin Neoplasms 2 | 69
Skin cancer 2 | 469
Uncombable hair syndrome 2 | 3
acute quadriplegic myopathy 2 | 1,158
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
head and neck cancer 2 | 271
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
periodontitis 2 | 293
Abnormal helices 1 | 11
Afro-textured hair 1 | 13
Alopecia areata 1 | 41
Autosomal recessive congenital ichthyosis 1 | 11
Autosomal recessive congenital ichthyosis 4B 1 | 13
Chloracne 1 | 32
Coarse hair 1 | 31
Corneal erosion 1 | 16
Dermatitis herpetiformis 1 | 12
Dry skin 1 | 75
Ectropion 1 | 38
Erythema 1 | 58
Esotropia 1 | 31
Everted lower lip vermilion 1 | 54
Exfoliative dermatitis 1 | 24
Exotropia 1 | 35
Flushing 1 | 60
Gastroenteritis 1 | 41
Hemophagocytic lymphohistiocytosis 1 | 30
Hypertrophic cardiomyopathy 20 1 | 12
Kinky hair texture 1 | 13
Lack of skin elasticity 1 | 10
Leiomyoma 1 | 32
Lichen planus 1 | 16
Myoma 1 | 12
Nail Diseases 1 | 24
Nail abnormality 1 | 22
Nappy hair texture 1 | 13
Neurotoxicity Syndromes 1 | 26
Nonepidermolytic palmoplantar keratoderma 1 | 12
Oculodentodigital dysplasia 1 | 14
Papilloma 1 | 44
Pilomatrixoma 1 | 12
Protruding lower lip 1 | 54
Pruritus 1 | 58
Rough hair texture 1 | 31
Seborrheic dermatitis 1 | 31
Silver-Russell syndrome 1 | 39
Stretched skin 1 | 10
Tooth agenesis 1 | 44
Uterine fibroid 1 | 28
White hair 1 | 7
Wooly hair 1 | 17
Xerosis 1 | 75
sarcoidosis 1 | 370

Tissue

Skin and soft tissues 38 | 17,230
Female tissues 36 | 17,400
Blood and immune system 30 | 16,909
Digestive Tract 29 | 17,369
Endocrine System 24 | 18,159
Liver and Pancreas 17 | 16,750
Urinary Tract 17 | 16,678
Nervous System 16 | 16,725
Cardiovascular System 13 | 15,192
Respiratory system 12 | 16,393
Male tissues 10 | 17,142

Target Family

Non-IDG 37 | 12,091
Enzyme 2 | 4,145

UniProt Keyword

Keratinization 39 | 39
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Late cornified envelope protein 5A LCE5A Tdark Non-IDG 0.50 0.32 0
Small proline-rich protein 4 SPRR4 Tdark Non-IDG -0.32647 2.13 9
Small proline-rich protein 2F SPRR2F Tbio Non-IDG 0.44 0.31 12
Small proline-rich protein 2G SPRR2G Tbio Non-IDG 0.39 0.31 1
Late cornified envelope protein 3D LCE3D Tdark Non-IDG -0.13175 1.11 0
Cornifelin CNFN Tdark Non-IDG -0.56002 3.82 7
Late cornified envelope protein 4A LCE4A Tdark Non-IDG 0.12 0.33 0
Late cornified envelope protein 2A LCE2A Tdark Non-IDG -0.17609 1.50 11
Late cornified envelope protein 3A LCE3A Tdark Non-IDG -0.37436 2.16 0
Late cornified envelope protein 3B LCE3B Tbio Non-IDG -1.17734 17.9 0