Development Level

Tdark 102 | 6,593
Tbio 47 | 11,651

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased circulating HDL chol... 2 | 68
decreased circulating insulin ... 2 | 76
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal kidney morphology 1 | 65
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased lean body mass 1 | 172
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

psoriasis 101 | 6,694
Carcinoma 67 | 11,493
diabetes mellitus 41 | 1,728
Atopic dermatitis 34 | 952
ovarian cancer 23 | 8,520
osteosarcoma 15 | 7,950
medulloblastoma, large-cell 14 | 6,241
Cancer 13 | 2,499
cystic fibrosis 13 | 1,696
spina bifida 13 | 1,074
Palmoplantar keratosis 12 | 74
non-small cell lung cancer 12 | 2,890
Dystrophia unguium 11 | 53
Monilethrix 11 | 18
esophageal adenocarcinoma 11 | 737
Breast cancer 10 | 3,578
Pachyonychia congenita 10 | 10
lung cancer 10 | 4,740
adult high grade glioma 9 | 3,801
nasopharyngeal carcinoma 9 | 1,058
Abnormal blistering of the skin 8 | 54
Blister of skin 8 | 54
Hyperhidrosis disorder 8 | 81
Increased sweating 8 | 81
Skin bulla 8 | 54
Sweating 8 | 81
malignant mesothelioma 8 | 3,232
Alopecia 7 | 115
Hereditary mucosal leukokeratosis 7 | 7
Hypotrichosis 7 | 47
Leukokeratosis 7 | 19
Leukoplakia, Oral 7 | 20
Epidermolytic hyperkeratosis 6 | 14
Keratosis 6 | 37
Nail Diseases 6 | 24
Nail abnormality 6 | 22
Nail dysplasia 6 | 52
Onychogryposis 6 | 13
breast carcinoma 6 | 1,638
cutaneous lupus erythematosus 6 | 1,057
ductal carcinoma in situ 6 | 1,745
pancreatic cancer 6 | 2,398
Abnormality of metabolism/homeostasis 5 | 134
Dental caries 5 | 164
Epidermolysis bullosa simplex 5 | 9
Erythema 5 | 58
Flushing 5 | 60
Highly variable severity 5 | 157
Ichthyoses 5 | 41
Kidney cancer 5 | 2,613
Papilloma 5 | 44
Rotting teeth 5 | 73
Variable expressivity 5 | 157
atypical teratoid / rhabdoid tumor 5 | 5,112
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
Abnormality of nail color 4 | 5
Adenoma 4 | 167
Ameloblastoma 4 | 24
Breast Neoplasms 4 | 445
Brittle hair 4 | 25
Carcinoma, Squamous Cell 4 | 110
Cell Transformation, Neoplastic 4 | 97
Congenital ichthyosiform erythroderma 4 | 28
Esophageal Squamous Cell Carcinoma 4 | 77
Fractured hair 4 | 25
Fragile hair 4 | 25
Liver disease 4 | 237
Mammary Neoplasms 4 | 425
Neoplastic Cell Transformation 4 | 89
Phrynoderma 4 | 11
Reduced tensile strength of hair 4 | 25
Squamous cell carcinoma 4 | 129
Squamous cell carcinoma of esophagus 4 | 77
Syringoma 4 | 11
colon cancer 4 | 1,478
glioblastoma 4 | 5,792
Abnormality of the fingernails 3 | 51
Anemia 3 | 365
Basal cell carcinoma 3 | 54
Carcinoma, Renal Cell 3 | 124
Contact Dermatitis 3 | 81
Corneal dystrophy 3 | 24
Dermatitis, Contact 3 | 71
Eczema 3 | 45
Fine hair 3 | 42
Infantile onset 3 | 238
Liver Cirrhosis, Experimental 3 | 769
Recurrent skin infections 3 | 21
Renal Cell Carcinoma 3 | 214
Skin Neoplasms 3 | 69
Skin disease 3 | 66
Slow-growing hair 3 | 19
Warts 3 | 10
Woolly hair, autosomal dominant 3 | 5
Woolly hair, congenital 3 | 5
Wooly hair 3 | 17
active ulcerative colitis 3 | 764
periodontitis 3 | 293
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 65 | 18,159
Female tissues 65 | 17,400
Skin and soft tissues 65 | 17,230
Digestive Tract 55 | 17,369
Blood and immune system 46 | 16,909
Male tissues 39 | 17,142
Liver and Pancreas 34 | 16,750
Nervous System 33 | 16,725
Respiratory system 30 | 16,393
Urinary Tract 27 | 16,678
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 149 | 12,091

UniProt Keyword

Keratin 149 | 149
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Keratin, type II cytoskeletal 6C KRT6C Tbio Non-IDG -0.47272 2.11 89
Keratin-associated protein 10-2 KRTAP10-2 Tdark Non-IDG 0.00000 5
Keratin-associated protein 10-3 KRTAP10-3 Tdark Non-IDG 1.08 0.05 0
Keratin-associated protein 10-1 KRTAP10-1 Tdark Non-IDG 0.48 0.20 0
Keratin-associated protein 10-6 KRTAP10-6 Tdark Non-IDG 0.00000 1
Keratin-associated protein 10-5 KRTAP10-5 Tdark Non-IDG 0.60 0.11 0
Keratin-associated protein 10-4 KRTAP10-4 Tdark Non-IDG 0.60 0.25 0
Keratin-associated protein 12-4 KRTAP12-4 Tdark Non-IDG 0.00000 0
Keratin-associated protein 12-3 KRTAP12-3 Tdark Non-IDG 1.23 0.05 0
Keratin, type I cytoskeletal 13 KRT13 Tbio Non-IDG -2.25522 171.2 403