Development Level

Tdark 39 | 6,588
Tbio 31 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent testes 1 | 6
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hypoactivity 1 | 132
impaired righting response 1 | 26
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased grip strength 1 | 41
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
prolonged PQ interval 1 | 5
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small thymus 1 | 16
tremors 1 | 39

Disease

Carcinoma 55 | 11,493
medulloblastoma, large-cell 37 | 6,241
osteosarcoma 35 | 7,950
ovarian cancer 31 | 8,520
glioblastoma 26 | 5,792
atypical teratoid / rhabdoid tumor 25 | 5,112
ependymoma 19 | 4,679
oligodendroglioma 18 | 2,850
psoriasis 17 | 6,694
adult high grade glioma 16 | 3,801
group 4 medulloblastoma 16 | 1,855
Astrocytoma, Pilocytic 15 | 3,081
Kidney cancer 15 | 2,613
invasive ductal carcinoma 15 | 2,951
Breast cancer 13 | 3,578
malignant mesothelioma 13 | 3,232
astrocytic glioma 12 | 2,597
group 3 medulloblastoma 12 | 4,104
lung cancer 12 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pituitary cancer 11 | 1,972
primitive neuroectodermal tumor 11 | 3,035
subependymal giant cell astrocytoma 11 | 2,287
interstitial cystitis 10 | 2,312
lung carcinoma 9 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
tuberculosis 9 | 2,010
Pick disease 8 | 1,894
pancreatic cancer 8 | 2,398
adrenocortical carcinoma 7 | 1,428
ulcerative colitis 7 | 1,819
aldosterone-producing adenoma 6 | 665
breast carcinoma 6 | 1,638
ductal carcinoma in situ 6 | 1,745
gastric carcinoma 6 | 807
hepatocellular carcinoma 6 | 547
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
acute quadriplegic myopathy 5 | 1,158
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
Autosomal recessive predisposition 4 | 1,442
Intellectual disability 4 | 1,016
Multiple myeloma 4 | 1,332
Nemaline myopathy 4 | 17
cystic fibrosis 4 | 1,696
gastric cancer 4 | 459
lung adenocarcinoma 4 | 2,716
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
tuberculosis and treatment for 6 months 4 | 409
Congenital myopathy 3 | 16
Dull intelligence 3 | 645
Low intelligence 3 | 645
Mental Depression 3 | 333
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Pseudohypoaldosteronism 3 | 23
Rheumatoid arthritis 3 | 1,191
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
sarcoidosis 3 | 370
sonic hedgehog group medulloblastoma 3 | 467
Acquired metabolic disease 2 | 336
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Byzanthine arch palate 2 | 194
Congenital clubfoot 2 | 109
Curvature of spine 2 | 282
Dysarthria 2 | 192
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Malaria 2 | 160
Midface retrusion 2 | 105
Multiple Sclerosis 2 | 540
Muscle Weakness 2 | 170
Orofacial cleft 2 | 54
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Pectus excavatum 2 | 100
Prostatic Neoplasms 2 | 495
Retinitis pigmentosa 11 2 | 59
Short neck 2 | 140
Short stature 2 | 531
Small midface 2 | 105
Type 2 diabetes mellitus 2 | 272
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
dermatomyositis 2 | 966
medulloblastoma 2 | 720
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
type II diabetes mellitus and post-ischemic heart failure 2 | 88

Tissue

Endocrine System 71 | 18,159
Male tissues 70 | 17,142
Nervous System 70 | 16,725
Skin and soft tissues 70 | 17,230
Digestive Tract 69 | 17,369
Blood and immune system 67 | 16,909
Female tissues 67 | 17,400
Liver and Pancreas 67 | 16,750
Respiratory system 67 | 16,393
Urinary Tract 67 | 16,678
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 71 | 12,091

UniProt Keyword

Kelch repeat 71 | 71
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kelch-like protein 5 KLHL5 Tdark Non-IDG 0.04 0.81 49
Kelch-like protein 21 KLHL21 Tbio Non-IDG -0.32074 2.17 65
Actin-binding protein IPP IPP Tdark Non-IDG -2.93193 840.1 31
Muskelin MKLN1 Tbio Non-IDG -1.08451 14.7 102
Kelch-like protein 32 KLHL32 Tdark Non-IDG 0.18 0.58 64
Kelch repeat and BTB domain-containing protein 6 KBTBD6 Tdark Non-IDG 0.85 0.22 40
Kelch repeat and BTB domain-containing protein 3 KBTBD3 Tdark Non-IDG 0.00000 57
Calicin CCIN Tbio Non-IDG -1.20185 15.2 106
Kelch repeat and BTB domain-containing protein 11 KBTBD11 Tdark Non-IDG -1.64897 39.6 26
Influenza virus NS1A-binding protein IVNS1ABP Tbio Non-IDG -1.07437 11.3 81