Development Level

Tbio 17 | 11,445
Tdark 4 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
decreased bone mineral content 1 | 151
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased body length 1 | 32
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
long tibia 1 | 25

Disease

Carcinoma 18 | 11,493
osteosarcoma 17 | 7,950
psoriasis 14 | 6,694
medulloblastoma, large-cell 13 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
ovarian cancer 12 | 8,520
glioblastoma 11 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
pancreatic cancer 11 | 2,398
tuberculosis 11 | 2,010
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
non-small cell lung cancer 10 | 2,890
adult high grade glioma 9 | 3,801
group 3 medulloblastoma 9 | 4,104
lung adenocarcinoma 9 | 2,716
lung carcinoma 9 | 2,843
pituitary cancer 9 | 1,972
Breast cancer 8 | 3,578
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Anemia 7 | 365
cystic fibrosis 7 | 1,696
malignant mesothelioma 7 | 3,232
primitive neuroectodermal tumor 7 | 3,035
diabetes mellitus 6 | 1,728
invasive ductal carcinoma 6 | 2,951
lung cancer 6 | 4,740
oligodendroglioma 6 | 2,850
Aceruloplasminemia 5 | 16
Hemochromatosis 5 | 54
adrenocortical carcinoma 5 | 1,428
hepatocellular carcinoma 5 | 547
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
mucosa-associated lymphoid tissue lymphoma 5 | 484
subependymal giant cell astrocytoma 5 | 2,287
Atopic dermatitis 4 | 952
Atransferrinemia 4 | 8
Autosomal recessive predisposition 4 | 1,442
Liver disease 4 | 237
active ulcerative colitis 4 | 764
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
interstitial cystitis 4 | 2,312
pancreatic carcinoma 4 | 562
ulcerative colitis 4 | 1,819
Arthropathy 3 | 43
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Chemical and Drug Induced Liver Injury 3 | 195
Congestive heart failure 3 | 113
Endometriosis 3 | 540
Friedreich ataxia 3 | 24
Heart failure 3 | 162
Hemoglobin low 3 | 124
Hyperferritinaemia 3 | 14
Increased ferritin 3 | 14
Inflammation 3 | 120
Iron deficiency anemia 3 | 12
Iron metabolism disease 3 | 20
Liver neoplasms 3 | 130
Obesity 3 | 678
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Serum ferritin increased 3 | 14
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467
Abnormality of the liver 2 | 21
Adenocarcinoma of lung 2 | 142
Alzheimer Disease 2 | 83
Alzheimer's disease 2 | 658
Autistic Disorder 2 | 364
Decreased joint mobility 2 | 53
Diarrhea 2 | 253
Heart disease 2 | 306
Hepatomegaly 2 | 285
Hypertension 2 | 396
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Liver diseases 2 | 87
Mesothelioma, Malignant 2 | 105
Neurodegenerative disease 2 | 414
Prostate cancer 2 | 175
Schizoaffective Disorder 2 | 55
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
cystic fibrosis and chronic rhinosinusitis 2 | 214
gastric carcinoma 2 | 807
medulloblastoma 2 | 720
spina bifida 2 | 1,074
substance-related disorder 2 | 162
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Non-IDG 12 | 12,091
Transporter 6 | 473
Enzyme 5 | 4,145

UniProt Keyword

Iron transport 23 | 23
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hephaestin HEPH Tbio Non-IDG -2.02535 102.7 111
Metalloreductase STEAP1 STEAP1 Tbio Enzyme -1.65454 46.2 322
Sideroflexin-4 SFXN4 Tbio Non-IDG -0.28426 2.10 77
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Metalloreductase STEAP2 STEAP2 Tbio Enzyme -1.78852 56.5 154
Natural resistance-associated macrophage protein 1 SLC11A1 Tbio Transporter -2.77524 629.3 129
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.53965 373.5 250
Mitoferrin-1 SLC25A37 Tbio Transporter -1.58954 37.6 97
Mitoferrin-2 SLC25A28 Tbio Transporter -1.06193 10.8 111
Metalloreductase STEAP4 STEAP4 Tbio Enzyme -1.59030 51.2 200