Development Level

Tbio 174 | 10,625
Tchem 74 | 1,890
Tdark 36 | 7,003
Tclin 34 | 602

IMPC Term

preweaning lethality, complete... 15 | 633
abnormal behavior 8 | 226
preweaning lethality, incomple... 7 | 260
abnormal lens morphology 6 | 73
decreased bone mineral content 6 | 157
decreased bone mineral density 6 | 126
decreased total body fat amoun... 6 | 186
abnormal bone structure 5 | 131
decreased grip strength 5 | 123
embryonic lethality prior to t... 5 | 187
hyperactivity 5 | 108
hypoactivity 5 | 89
abnormal retina morphology 4 | 100
decreased body weight 4 | 174
decreased circulating triglyce... 4 | 83
decreased heart weight 4 | 44
decreased lean body mass 4 | 195
embryonic lethality prior to o... 4 | 148
increased bone mineral content 4 | 92
abnormal embryo size 3 | 112
cataract 3 | 26
decreased circulating insulin ... 3 | 75
decreased circulating iron lev... 3 | 25
decreased circulating serum al... 3 | 79
decreased fasted circulating g... 3 | 49
decreased leukocyte cell numbe... 3 | 54
decreased vertical activity 3 | 22
embryonic growth retardation 3 | 28
enlarged heart 3 | 111
increased B cell number 3 | 23
increased circulating alkaline... 3 | 119
increased circulating triglyce... 3 | 24
increased or absent threshold ... 3 | 128
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal coat/ hair morphology 2 | 18
abnormal coping response 2 | 12
abnormal cranium morphology 2 | 32
abnormal eye morphology 2 | 38
abnormal femur morphology 2 | 14
abnormal gait 2 | 51
abnormal glucose homeostasis 2 | 5
abnormal iris morphology 2 | 12
abnormal locomotor activation 2 | 26
abnormal retinal blood vessel ... 2 | 18
decreased blood urea nitrogen ... 2 | 31
decreased caudal vertebrae num... 2 | 49
decreased circulating LDL chol... 2 | 37
decreased circulating amylase ... 2 | 24
decreased circulating calcium ... 2 | 33
decreased circulating choleste... 2 | 85
decreased circulating phosphat... 2 | 15
decreased circulating total pr... 2 | 41
decreased follicular B cell nu... 2 | 4
decreased hemoglobin content 2 | 53
decreased lactate dehydrogenas... 2 | 14
decreased mean platelet volume 2 | 12
decreased red blood cell distr... 2 | 11
impaired righting response 2 | 19
improved glucose tolerance 2 | 56
increased circulating choleste... 2 | 53
increased circulating creatini... 2 | 29
increased circulating iron lev... 2 | 25
increased circulating potassiu... 2 | 31
increased circulating serum al... 2 | 25
increased erythrocyte cell num... 2 | 26
increased fasted circulating g... 2 | 68
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 93
increased startle reflex 2 | 38
mydriasis 2 | 9
short tibia 2 | 82
small kidney 2 | 10
vertebral transformation 2 | 12
abnormal QRS complex 1 | 25
abnormal embryo turning 1 | 15
abnormal heart morphology 1 | 51
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal response to new envir... 1 | 8
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
decreased cardiac muscle contr... 1 | 5
decreased cervical vertebrae n... 1 | 12
decreased circulating magnesiu... 1 | 11
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart rate 1 | 10
decreased hematocrit 1 | 25
decreased mean corpuscular hem... 1 | 34
enlarged lymph nodes 1 | 27
increased blood urea nitrogen ... 1 | 44
increased circulating amylase ... 1 | 13
increased rib number 1 | 41
limb grasping 1 | 35
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

ovarian cancer 147 | 8,484
psoriasis 137 | 6,685
osteosarcoma 135 | 7,933
medulloblastoma, large-cell 106 | 6,234
lung cancer 88 | 4,466
glioblastoma 85 | 5,572
Cancer 72 | 2,346
non-small cell lung cancer 70 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 69 | 3,289
malignant mesothelioma 64 | 3,162
atypical teratoid / rhabdoid tumor 63 | 4,369
pancreatic ductal adenocarcinoma liver metastasis 62 | 1,795
intraductal papillary-mucinous adenoma (IPMA) 61 | 2,956
lung adenocarcinoma 58 | 2,713
lung carcinoma 58 | 2,844
pancreatic cancer 57 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,988
invasive ductal carcinoma 55 | 2,950
primitive neuroectodermal tumor 53 | 3,031
Breast cancer 52 | 3,094
oligodendroglioma 51 | 2,849
interstitial cystitis 48 | 2,299
ulcerative colitis 47 | 2,087
tuberculosis 46 | 1,557
group 3 medulloblastoma 45 | 2,254
ependymoma 44 | 2,514
pediatric high grade glioma 42 | 2,712
pilocytic astrocytoma 42 | 3,086
adrenocortical carcinoma 40 | 1,427
cystic fibrosis 40 | 1,665
subependymal giant cell astrocytoma 40 | 2,287
ductal carcinoma in situ 39 | 1,745
adult high grade glioma 38 | 2,148
astrocytic glioma 37 | 2,241
diabetes mellitus 37 | 1,663
pituitary cancer 35 | 1,972
Pick disease 33 | 1,893
breast carcinoma 33 | 1,614
Carcinoma 29 | 2,147
group 4 medulloblastoma 29 | 1,875
posterior fossa group A ependymoma 29 | 1,511
medulloblastoma 28 | 1,524
astrocytoma 27 | 1,493
primary pancreatic ductal adenocarcinoma 27 | 1,271
atypical teratoid/rhabdoid tumor 26 | 1,095
Prostatic Neoplasms 25 | 471
aldosterone-producing adenoma 25 | 664
Anemia 23 | 252
Atopic dermatitis 23 | 944
Rheumatoid Arthritis 23 | 1,160
Hypertension 22 | 287
active Crohn's disease 22 | 918
colon cancer 22 | 1,475
Obesity 21 | 616
cutaneous lupus erythematosus 21 | 1,056
non primary Sjogren syndrome sicca 21 | 840
sonic hedgehog group medulloblastoma 20 | 1,482
Kidney disease 19 | 396
Multiple myeloma 18 | 1,327
pancreatic carcinoma 18 | 567
Alzheimer's disease 17 | 644
Schizophrenia 17 | 501
acute myeloid leukemia 17 | 780
chronic rhinosinusitis 17 | 512
esophageal adenocarcinoma 17 | 737
Atherosclerosis 16 | 275
Autistic Disorder 16 | 320
Endometriosis 16 | 535
Liver disease 16 | 219
Mammary Neoplasms 16 | 410
nasopharyngeal carcinoma 16 | 1,056
Vascular disease 14 | 281
gastric carcinoma 14 | 832
hepatocellular carcinoma 14 | 532
juvenile dermatomyositis 14 | 1,189
posterior fossa group B ependymoma 14 | 1,530
spina bifida 14 | 1,064
Drug-Induced Liver Injury 13 | 118
Malaria 13 | 140
Parkinson's disease 13 | 364
Peripheral Neuropathy 13 | 303
acute quadriplegic myopathy 13 | 1,157
dermatomyositis 13 | 933
mucosa-associated lymphoid tissue lymphoma 13 | 480
Cerebrovascular disease 12 | 231
Hypertensive disease 12 | 193
Lung Neoplasms 12 | 171
Neurodegenerative disease 12 | 383
Asthma 11 | 349
Diabetes Mellitus, Non-Insulin-Dependent 11 | 157
Heart disease 11 | 279
Polycystic Ovary Syndrome 11 | 332
Thalassemia 11 | 46
active ulcerative colitis 11 | 477
fibroadenoma 11 | 557
Duchenne muscular dystrophy 10 | 602
Intellectual disability 10 | 573
gastric cancer 10 | 430
periodontitis 10 | 269
primary Sjogren syndrome 10 | 789

Tissue

Female tissues 313 | 18,647
Blood and immune system 312 | 17,995
Digestive Tract 312 | 18,473
Endocrine System 312 | 18,512
Liver and Pancreas 312 | 18,136
Nervous System 312 | 18,561
Cardiovascular System 311 | 17,958
Male tissues 310 | 17,969
Urinary Tract 310 | 18,444
Skin and soft tissues 309 | 18,115
Respiratory system 305 | 17,484

Target Family

Enzyme 168 | 4,146
Non-IDG 115 | 11,971
Epigenetic 20 | 242
Transporter 6 | 473
TF/Epigenetic 4 | 38
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400
Ion Channel 1 | 341

UniProt Keyword

Iron 318 | 318
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysine-specific demethylase 3B KDM3B Tbio Epigenetic -0.92399 9.25 269
Indoleamine 2,3-dioxygenase 2 IDO2 Tchem Enzyme -1.88853 82.2 208
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 OGFOD2 Tdark Enzyme 0.00000 75
24-hydroxycholesterol 7-alpha-hydroxylase CYP39A1 Tbio Enzyme -0.95411 6.43 97
Cytochrome b MT-CYB Tbio Non-IDG -3.74473 5676.0 122
Cytochrome b561 CYB561 Tbio Non-IDG -1.41910 20.4 45
Ferritin heavy chain FTH1 Tbio Non-IDG -2.95630 924.5 435
Cytochrome b5 CYB5A Tchem Non-IDG -3.24788 1711.2 249
Microprocessor complex subunit DGCR8 DGCR8 Tbio Non-IDG -2.41582 254.1 201