Development Level

Tbio 237 | 11,445
Tchem 36 | 1,598
Tclin 16 | 613
Tdark 2 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal behavior 8 | 298
decreased mean corpuscular vol... 6 | 79
abnormal bone structure 5 | 187
decreased bone mineral content 5 | 151
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
decreased blood urea nitrogen ... 3 | 51
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
hypoactivity 3 | 132
increased circulating sodium l... 3 | 71
increased mean corpuscular vol... 3 | 92
increased neutrophil cell numb... 3 | 46
small superior vagus ganglion 3 | 74
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
cardiovascular system phenotyp... 2 | 36
decreased CD8-positive, alpha-... 2 | 8
decreased T cell number 2 | 15
decreased bone mineral density 2 | 126
decreased circulating iron lev... 2 | 32
decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased circulating alanine ... 2 | 13
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased startle reflex 2 | 112
prolonged QRS complex duration 2 | 8
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal esophagus morphology 1 | 5
abnormal hair growth 1 | 10
abnormal joint morphology 1 | 23
abnormal midbrain development 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired righting response 1 | 26
increased aggression 1 | 4
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened RR interval 1 | 17
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 186 | 11,493
ovarian cancer 160 | 8,520
psoriasis 146 | 6,694
osteosarcoma 141 | 7,950
lung cancer 126 | 4,740
glioblastoma 116 | 5,792
lung carcinoma 107 | 2,843
medulloblastoma, large-cell 103 | 6,241
tuberculosis 88 | 2,010
Cancer 83 | 2,499
interstitial cystitis 83 | 2,312
malignant mesothelioma 82 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 79 | 3,291
adult high grade glioma 73 | 3,801
cutaneous lupus erythematosus 73 | 1,057
Astrocytoma, Pilocytic 70 | 3,081
ulcerative colitis 70 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 69 | 2,955
non-small cell lung cancer 69 | 2,890
lung adenocarcinoma 65 | 2,716
subependymal giant cell astrocytoma 65 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 64 | 2,989
invasive ductal carcinoma 63 | 2,951
pancreatic cancer 61 | 2,398
ependymoma 60 | 4,679
juvenile dermatomyositis 59 | 1,187
Breast cancer 57 | 3,578
cystic fibrosis 56 | 1,696
atypical teratoid / rhabdoid tumor 52 | 5,112
dermatomyositis 52 | 966
pancreatic ductal adenocarcinoma liver metastasis 52 | 1,962
primary Sjogren syndrome 52 | 735
group 3 medulloblastoma 49 | 4,104
Kidney cancer 45 | 2,613
Systemic lupus erythematosus 45 | 194
Rheumatoid arthritis 42 | 1,191
Multiple Sclerosis 40 | 540
active Crohn's disease 39 | 922
diabetes mellitus 36 | 1,728
group 4 medulloblastoma 36 | 1,855
pituitary cancer 36 | 1,972
astrocytoma 35 | 1,146
Autosomal recessive predisposition 34 | 1,442
adrenocortical carcinoma 34 | 1,428
Influenza 33 | 142
Liver Cirrhosis, Experimental 32 | 769
acute quadriplegic myopathy 30 | 1,158
mucosa-associated lymphoid tissue lymphoma 30 | 484
breast carcinoma 29 | 1,638
oligodendroglioma 29 | 2,850
Atopic dermatitis 28 | 952
Melanoma 28 | 711
Multiple myeloma 28 | 1,332
Schizophrenia 28 | 1,160
astrocytic glioma 28 | 2,597
esophageal adenocarcinoma 27 | 737
Duchenne muscular dystrophy 25 | 601
colon cancer 25 | 1,478
Arthritis 24 | 290
nasopharyngeal carcinoma 24 | 1,058
primitive neuroectodermal tumor 24 | 3,035
active ulcerative colitis 23 | 764
gastric carcinoma 23 | 807
Kidney disease 22 | 430
ductal carcinoma in situ 21 | 1,745
Influenza, Human 20 | 51
head and neck cancer and chronic obstructive pulmonary disease 20 | 239
Hypersensitivity reaction type II disease 19 | 253
Meningitis 19 | 67
Asthma 18 | 385
Microphthalmia with limb anomalies 18 | 40
Prostatic Neoplasms 18 | 495
Waldenstrons macroglobulinemia 18 | 765
chronic lymphosyte leukemia 18 | 204
hepatocellular carcinoma 18 | 547
pancreatic carcinoma 18 | 562
pediatric high grade glioma 18 | 1,064
primary pancreatic ductal adenocarcinoma 18 | 1,109
Immunologic Deficiency Syndromes 17 | 113
Skin cancer 17 | 469
aldosterone-producing adenoma 17 | 665
limb girdle muscular dystrophy 2A 17 | 213
spina bifida 17 | 1,074
Pick disease 16 | 1,894
acute myeloid leukemia 16 | 783
non primary Sjogren syndrome sicca 16 | 891
periodontitis 16 | 293
Chemical and Drug Induced Liver Injury 15 | 195
Inflammatory bowel disease 15 | 151
Vascular disease 15 | 319
Bipolar Disorder 14 | 666
Crohn's disease 14 | 321
Lupus Erythematosus, Systemic 14 | 67
Obesity 14 | 678
Pneumonia 14 | 174
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
Down syndrome 13 | 499
Lupus erythematosus 13 | 57
gastric cancer 13 | 459
nephrosclerosis 13 | 333

Tissue

Blood and immune system 284 | 16,909
Digestive Tract 283 | 17,369
Female tissues 283 | 17,400
Skin and soft tissues 283 | 17,230
Endocrine System 282 | 18,159
Liver and Pancreas 279 | 16,750
Respiratory system 277 | 16,393
Urinary Tract 277 | 16,678
Male tissues 272 | 17,142
Nervous System 263 | 16,725
Cardiovascular System 257 | 15,192

Target Family

Non-IDG 190 | 12,091
Enzyme 60 | 4,145
Kinase 21 | 634
Transcription Factor 11 | 1,400
GPCR 4 | 408
Epigenetic 2 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Innate immunity 291 | 291
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Spondin-2 SPON2 Tbio Non-IDG -1.73555 56.2 210
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.43609 25.1 193
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
NACHT, LRR and PYD domains-containing protein 2 NLRP2 Tbio Non-IDG -1.82146 68.5 245
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
RNA-binding protein 14 RBM14 Tbio Non-IDG -2.10043 124.7 168
Arginase-2, mitochondrial ARG2 Tchem Enzyme -2.46702 275.2 245
E3 ISG15--protein ligase HERC5 HERC5 Tbio Enzyme -1.63055 44.5 57