Development Level

Tbio 200 | 10,625
Tchem 36 | 1,890
Tclin 16 | 602
Tdark 4 | 7,003

IMPC Term

decreased bone mineral content 4 | 157
embryonic lethality prior to t... 4 | 187
increased circulating HDL chol... 4 | 63
preweaning lethality, complete... 4 | 633
abnormal behavior 3 | 226
abnormal embryo size 3 | 112
decreased CD4-positive, CD25-p... 3 | 24
decreased circulating glucose ... 3 | 121
decreased grip strength 3 | 123
decreased neutrophil cell numb... 3 | 37
decreased total body fat amoun... 3 | 186
embryonic lethality prior to o... 3 | 148
increased circulating choleste... 3 | 53
increased circulating sodium l... 3 | 71
increased mean corpuscular hem... 3 | 93
abnormal bone structure 2 | 131
abnormal neural tube closure 2 | 37
decreased B cell number 2 | 30
decreased CD8-positive, alpha-... 2 | 26
decreased bone mineral density 2 | 126
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
enlarged heart 2 | 111
hyperactivity 2 | 108
increased bone mineral content 2 | 92
increased circulating alanine ... 2 | 11
increased mean corpuscular vol... 2 | 91
small superior vagus ganglion 2 | 20
abnormal behavioral response t... 1 | 52
abnormal forebrain development 1 | 18
abnormal hair growth 1 | 8
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal midbrain development 1 | 22
abnormal placenta size 1 | 10
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 35
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating magnesiu... 1 | 11
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased monocyte cell number 1 | 28
decreased rib number 1 | 59
enlarged lymph nodes 1 | 27
enlarged urinary bladder 1 | 4
female infertility 1 | 34
hydrometra 1 | 13
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased CD4-positive, alpha ... 1 | 15
increased NK cell number 1 | 19
increased aggression 1 | 2
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean platelet volume 1 | 19
increased vertical activity 1 | 18
oligodactyly 1 | 14
pale yolk sac 1 | 12
pallor 1 | 13
shortened PQ interval 1 | 6
shortened RR interval 1 | 19
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 139 | 8,484
psoriasis 127 | 6,685
osteosarcoma 116 | 7,933
lung cancer 115 | 4,466
lung carcinoma 103 | 2,844
glioblastoma 96 | 5,572
medulloblastoma, large-cell 89 | 6,234
ulcerative colitis 79 | 2,087
interstitial cystitis 76 | 2,299
tuberculosis 72 | 1,557
Cancer 71 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 71 | 3,289
malignant mesothelioma 71 | 3,162
cutaneous lupus erythematosus 70 | 1,056
pilocytic astrocytoma 65 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 64 | 2,956
non-small cell lung cancer 61 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 60 | 2,988
subependymal giant cell astrocytoma 60 | 2,287
lung adenocarcinoma 59 | 2,713
invasive ductal carcinoma 56 | 2,950
juvenile dermatomyositis 55 | 1,189
pancreatic cancer 55 | 2,300
cystic fibrosis 54 | 1,665
primary Sjogren syndrome 49 | 789
dermatomyositis 48 | 933
Breast cancer 43 | 3,094
pediatric high grade glioma 43 | 2,712
pancreatic ductal adenocarcinoma liver metastasis 41 | 1,795
Rheumatoid Arthritis 40 | 1,160
atypical teratoid / rhabdoid tumor 38 | 4,369
systemic lupus erythematosus 37 | 156
Multiple Sclerosis 36 | 498
pituitary cancer 35 | 1,972
active Crohn's disease 34 | 918
adult high grade glioma 34 | 2,148
astrocytoma 34 | 1,493
group 4 medulloblastoma 34 | 1,875
Carcinoma 33 | 2,147
Influenza 32 | 142
adrenocortical carcinoma 31 | 1,427
posterior fossa group A ependymoma 31 | 1,511
group 3 medulloblastoma 29 | 2,254
diabetes mellitus 27 | 1,663
mucosa-associated lymphoid tissue lymphoma 27 | 480
acute quadriplegic myopathy 26 | 1,157
breast carcinoma 26 | 1,614
esophageal adenocarcinoma 26 | 737
Atopic dermatitis 25 | 944
Duchenne muscular dystrophy 24 | 602
Multiple myeloma 24 | 1,327
Lupus erythematosus 23 | 80
gastric carcinoma 23 | 832
primary pancreatic ductal adenocarcinoma 23 | 1,271
IGA Glomerulonephritis 21 | 454
nasopharyngeal carcinoma 21 | 1,056
oligodendroglioma 21 | 2,849
chronic lymphosyte leukemia 20 | 232
colon cancer 20 | 1,475
Arthritis 19 | 248
Kidney disease 19 | 396
head and neck cancer and chronic obstructive pulmonary disease 19 | 237
primitive neuroectodermal tumor 19 | 3,031
ductal carcinoma in situ 18 | 1,745
posterior fossa group B ependymoma 18 | 1,530
astrocytic glioma 17 | 2,241
hepatocellular carcinoma 17 | 532
ependymoma 16 | 2,514
pancreatic carcinoma 16 | 567
Prostatic Neoplasms 15 | 471
aldosterone-producing adenoma 15 | 664
Down syndrome 14 | 548
Hypersensitivity reaction type II disease 14 | 235
Inflammatory bowel disease 14 | 142
Pick disease 14 | 1,893
Waldenstrons macroglobulinemia 14 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 499
limb girdle muscular dystrophy 2A 14 | 156
Asthma 13 | 349
Complement deficiency 13 | 15
Crohn's disease 13 | 304
Melanoma 13 | 261
acute myeloid leukemia 13 | 780
gastric cancer 13 | 430
spina bifida 13 | 1,064
Human immunodeficiency virus infectious disease 12 | 92
Inflammation 12 | 109
Meningitis 12 | 46
Obesity 12 | 616
Vascular disease 12 | 281
medulloblastoma 12 | 1,524
periodontitis 12 | 269
tuberculosis and treatment for 6 months 12 | 686
Becker muscular dystrophy 11 | 187
Drug-Induced Liver Injury 11 | 118
glioblastoma multiforme 11 | 347
nephrosclerosis 11 | 329
non primary Sjogren syndrome sicca 11 | 840
Endometriosis 10 | 535
Schizophrenia 10 | 501

Tissue

Blood and immune system 255 | 17,995
Female tissues 255 | 18,647
Nervous System 255 | 18,561
Urinary Tract 255 | 18,444
Digestive Tract 254 | 18,473
Cardiovascular System 253 | 17,958
Endocrine System 253 | 18,512
Skin and soft tissues 253 | 18,115
Liver and Pancreas 251 | 18,136
Respiratory system 250 | 17,484
Male tissues 246 | 17,969

Target Family

Non-IDG 170 | 11,971
Enzyme 51 | 4,146
Kinase 19 | 634
Transcription Factor 10 | 1,400
GPCR 3 | 406
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Innate immunity 256 | 256
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
Antileukoproteinase SLPI Tbio Enzyme -2.56514 434.2 290
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
Properdin CFP Tbio Non-IDG -3.16935 1491.5 297
Natural killer cell receptor 2B4 CD244 Tbio Non-IDG -2.27438 190.1 418
Fibrinogen alpha chain FGA Tbio Non-IDG -2.84597 716.2 457
A-kinase anchor protein 8 AKAP8 Tbio Enzyme -1.32097 22.6 240
Complement component 1 Q subcomponent-binding protein, mitochondrial C1QBP Tbio Non-IDG -2.51978 332.6 298
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
NKG2-D type II integral membrane protein KLRK1 Tbio Non-IDG -1.48442 31.1 337