Development Level

Tbio 112 | 11,445
Tchem 28 | 1,598
Tclin 12 | 613
Tdark 1 | 6,588

Collection

RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased vertical activity 3 | 208
hypoactivity 3 | 132
increased circulating HDL chol... 3 | 80
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
increased bone mineral content 2 | 108
increased circulating alanine ... 2 | 13
increased circulating aspartat... 2 | 15
increased circulating choleste... 2 | 66
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent testes 1 | 6
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating alanine ... 1 | 47
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged uterus 1 | 11
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased IgG2b level 1 | 1
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

psoriasis 89 | 6,694
Carcinoma 86 | 11,493
lung cancer 72 | 4,740
ovarian cancer 72 | 8,520
glioblastoma 66 | 5,792
lung carcinoma 66 | 2,843
tuberculosis 61 | 2,010
Cancer 58 | 2,499
osteosarcoma 57 | 7,950
interstitial cystitis 55 | 2,312
medulloblastoma, large-cell 54 | 6,241
malignant mesothelioma 52 | 3,232
ulcerative colitis 47 | 1,819
adult high grade glioma 44 | 3,801
non-small cell lung cancer 44 | 2,890
Astrocytoma, Pilocytic 40 | 3,081
cutaneous lupus erythematosus 40 | 1,057
lung adenocarcinoma 39 | 2,716
cystic fibrosis 38 | 1,696
ependymoma 36 | 4,679
subependymal giant cell astrocytoma 35 | 2,287
Breast cancer 34 | 3,578
diabetes mellitus 34 | 1,728
invasive ductal carcinoma 34 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
Rheumatoid arthritis 30 | 1,191
Arthritis 29 | 290
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
Asthma 28 | 385
atypical teratoid / rhabdoid tumor 28 | 5,112
group 3 medulloblastoma 28 | 4,104
pancreatic cancer 27 | 2,398
Inflammatory bowel disease 26 | 151
Kidney cancer 26 | 2,613
pituitary cancer 24 | 1,972
Hypersensitivity reaction type II disease 22 | 253
Liver Cirrhosis, Experimental 22 | 769
Lung disease 22 | 142
Multiple Sclerosis 22 | 540
active Crohn's disease 21 | 922
Dermatitis 20 | 157
Influenza 20 | 142
Schizophrenia 20 | 1,160
colon cancer 20 | 1,478
gastric carcinoma 20 | 807
juvenile dermatomyositis 20 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Atherosclerosis 19 | 291
primary Sjogren syndrome 19 | 735
Inflammation 18 | 120
Kidney disease 18 | 430
Pneumonia 18 | 174
head and neck cancer and chronic obstructive pulmonary disease 18 | 239
mucosa-associated lymphoid tissue lymphoma 18 | 484
Vascular disease 17 | 319
active ulcerative colitis 17 | 764
breast carcinoma 17 | 1,638
ductal carcinoma in situ 17 | 1,745
nasopharyngeal carcinoma 17 | 1,058
primitive neuroectodermal tumor 17 | 3,035
Allergic hypersensitivity disease 16 | 126
adrenocortical carcinoma 16 | 1,428
Malaria 15 | 160
Obesity 15 | 678
periodontitis 15 | 293
Hypersensitivity 14 | 63
Meningitis 14 | 67
astrocytic glioma 14 | 2,597
astrocytoma 14 | 1,146
dermatomyositis 14 | 966
esophageal adenocarcinoma 14 | 737
oligodendroglioma 14 | 2,850
Atopic dermatitis 13 | 952
Bipolar Disorder 13 | 666
Breast Neoplasms 13 | 445
Human immunodeficiency virus infectious disease 13 | 138
Mammary Neoplasms 13 | 425
group 4 medulloblastoma 13 | 1,855
hepatocellular carcinoma 13 | 547
spina bifida 13 | 1,074
Arthritis, Rheumatoid 12 | 174
Coronary artery disease 12 | 268
Hypertension 12 | 396
Peritonitis 12 | 43
aldosterone-producing adenoma 12 | 665
Brain Injuries 11 | 65
Glomerulonephritis 11 | 46
Liver disease 11 | 237
Mesothelioma, Malignant 11 | 105
Prostatic Neoplasms 11 | 495
Reperfusion Injury 11 | 86
sarcoidosis 11 | 370
Endometriosis 10 | 540
Hypereosinophilic syndrome 10 | 71
Melanoma 10 | 711
Pancreatitis 10 | 123
Systemic lupus erythematosus 10 | 194
chronic lymphosyte leukemia 10 | 204
head and neck cancer 10 | 271

Tissue

Female tissues 150 | 17,400
Skin and soft tissues 150 | 17,230
Blood and immune system 149 | 16,909
Digestive Tract 149 | 17,369
Endocrine System 149 | 18,159
Liver and Pancreas 146 | 16,750
Male tissues 144 | 17,142
Respiratory system 144 | 16,393
Urinary Tract 144 | 16,678
Nervous System 134 | 16,725
Cardiovascular System 126 | 15,192

Target Family

Non-IDG 109 | 12,091
Enzyme 18 | 4,145
Kinase 12 | 634
GPCR 7 | 408
Transcription Factor 5 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

UniProt Keyword

Inflammatory response 153 | 153
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT, LRR and PYD domains-containing protein 2 NLRP2 Tbio Non-IDG -1.82146 68.5 245
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.93036 825.2 985
Stabilin-1 STAB1 Tbio Non-IDG -1.61013 45.4 107
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
Zinc finger protein 580 ZNF580 Tbio Transcription Factor -1.04597 11.4 74
C-C motif chemokine 13 CCL13 Tbio Non-IDG -2.02640 99.2 264
Plasminogen receptor (KT) PLGRKT Tbio Non-IDG -0.62045 4.93 72
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Latexin LXN Tbio Enzyme -2.54426 344.4 419