Development Level

Tbio 350 | 11,445
Tdark 221 | 6,588
Tclin 35 | 613
Tchem 19 | 1,598

Collection

RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Complete... 2 | 25
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 14 | 499
abnormal behavior 9 | 298
enlarged heart 9 | 210
preweaning lethality, complete... 7 | 979
abnormal heart morphology 6 | 162
decreased total body fat amoun... 6 | 207
abnormal gait 5 | 69
abnormal seminal vesicle morph... 5 | 114
decreased grip strength 5 | 116
abnormal bone structure 4 | 187
decreased circulating glucose ... 4 | 126
decreased leukocyte cell numbe... 4 | 73
decreased vertical activity 4 | 208
increased heart weight 4 | 62
male infertility 4 | 123
abnormal sleep behavior 3 | 70
decreased body length 3 | 101
decreased bone mineral content 3 | 151
decreased fasted circulating g... 3 | 65
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
hypoactivity 3 | 132
impaired righting response 3 | 26
increased circulating iron lev... 3 | 30
increased circulating triglyce... 3 | 42
increased lean body mass 3 | 172
increased monocyte cell number 3 | 63
increased or absent threshold ... 3 | 101
increased vertical activity 3 | 24
small superior vagus ganglion 3 | 74
tremors 3 | 39
abnormal coat-hair pigmentatio... 2 | 64
abnormal ear morphology 2 | 9
abnormal embryo size 2 | 220
abnormal eye anterior chamber ... 2 | 9
abnormal response to new envir... 2 | 10
abnormal skin morphology 2 | 50
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating total pr... 2 | 49
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
enlarged spleen 2 | 41
hydrometra 2 | 53
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased circulating alanine ... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating bilirubi... 2 | 16
increased circulating choleste... 2 | 66
increased circulating potassiu... 2 | 29
increased circulating sodium l... 2 | 71
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
short tibia 2 | 97
thick ventricular wall 2 | 7
thrombocytopenia 2 | 56
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
persistence of hyaloid vascula... 1 | 33
thrombocytosis 1 | 27

Disease

Carcinoma 326 | 11,493
osteosarcoma 241 | 7,950
psoriasis 230 | 6,694
ovarian cancer 195 | 8,520
medulloblastoma, large-cell 170 | 6,241
glioblastoma 165 | 5,792
lung cancer 164 | 4,740
interstitial cystitis 144 | 2,312
lung carcinoma 139 | 2,843
atypical teratoid / rhabdoid tumor 131 | 5,112
adult high grade glioma 126 | 3,801
ependymoma 121 | 4,679
invasive ductal carcinoma 118 | 2,951
non-small cell lung cancer 117 | 2,890
ulcerative colitis 114 | 1,819
Breast cancer 113 | 3,578
Cancer 112 | 2,499
lung adenocarcinoma 110 | 2,716
group 3 medulloblastoma 103 | 4,104
Astrocytoma, Pilocytic 102 | 3,081
Kidney cancer 99 | 2,613
tuberculosis 95 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 87 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 86 | 3,291
malignant mesothelioma 86 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 81 | 2,955
cutaneous lupus erythematosus 79 | 1,057
oligodendroglioma 78 | 2,850
pancreatic cancer 75 | 2,398
subependymal giant cell astrocytoma 73 | 2,287
pituitary cancer 71 | 1,972
ductal carcinoma in situ 64 | 1,745
primitive neuroectodermal tumor 62 | 3,035
astrocytic glioma 59 | 2,597
cystic fibrosis 59 | 1,696
breast carcinoma 56 | 1,638
colon cancer 55 | 1,478
primary Sjogren syndrome 55 | 735
Rheumatoid arthritis 51 | 1,191
group 4 medulloblastoma 48 | 1,855
Schizophrenia 47 | 1,160
primary pancreatic ductal adenocarcinoma 45 | 1,109
Autosomal recessive predisposition 44 | 1,442
diabetes mellitus 42 | 1,728
Liver cancer 39 | 604
Melanoma 39 | 711
adrenocortical carcinoma 39 | 1,428
mucosa-associated lymphoid tissue lymphoma 35 | 484
nasopharyngeal carcinoma 35 | 1,058
Pick disease 34 | 1,894
Skin cancer 34 | 469
Multiple Sclerosis 32 | 540
periodontitis 31 | 293
Duchenne muscular dystrophy 29 | 601
active Crohn's disease 29 | 922
Atopic dermatitis 28 | 952
Multiple myeloma 28 | 1,332
astrocytoma 28 | 1,146
gastric carcinoma 28 | 807
Liver Cirrhosis, Experimental 27 | 769
Hypersensitivity reaction type II disease 26 | 253
esophageal adenocarcinoma 26 | 737
juvenile dermatomyositis 25 | 1,187
chronic lymphosyte leukemia 24 | 204
Asthma 23 | 385
pediatric high grade glioma 23 | 1,064
fibroadenoma 22 | 559
posterior fossa group A ependymoma 22 | 468
Intellectual disability 21 | 1,016
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
Down syndrome 20 | 499
Kidney disease 20 | 430
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 510
head and neck cancer and chronic obstructive pulmonary disease 20 | 239
non-small cell lung carcinoma 20 | 317
Alzheimer's disease 19 | 658
Bipolar Disorder 19 | 666
Anemia 18 | 365
Autistic Disorder 18 | 364
Renal Cell Carcinoma 18 | 214
dermatomyositis 18 | 966
sarcoidosis 18 | 370
Human immunodeficiency virus infectious disease 17 | 138
Lymphoproliferative syndrome 17 | 58
acute quadriplegic myopathy 17 | 1,158
aldosterone-producing adenoma 17 | 665
medulloblastoma 17 | 720
active ulcerative colitis 16 | 764
pancreatic carcinoma 16 | 562
spina bifida 16 | 1,074
urothelial carcinoma 16 | 318
Arthritis 15 | 290
Breast Neoplasms 15 | 445
Endometriosis 15 | 540
gastric cancer 15 | 459
Allergic hypersensitivity disease 14 | 126
Atherosclerosis 14 | 291
Epilepsy 14 | 792
non primary Sjogren syndrome sicca 14 | 891
progressive supranuclear palsy 14 | 676

Tissue

Digestive Tract 422 | 17,369
Endocrine System 422 | 18,159
Blood and immune system 421 | 16,909
Female tissues 417 | 17,400
Skin and soft tissues 415 | 17,230
Male tissues 404 | 17,142
Urinary Tract 403 | 16,678
Respiratory system 401 | 16,393
Liver and Pancreas 396 | 16,750
Nervous System 390 | 16,725
Cardiovascular System 351 | 15,192

Target Family

Non-IDG 575 | 12,091
Kinase 32 | 634
Enzyme 11 | 4,145
Ion Channel 4 | 344
GPCR 3 | 408

UniProt Keyword

Immunoglobulin domain 625 | 625
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314
Butyrophilin-like protein 2 BTNL2 Tbio Non-IDG -2.57312 369.3 73
Immunoglobulin heavy variable 7-4-1 IGHV7-4-1 Tdark Non-IDG 0.00000 0
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.89275 74.1 161
Hyaluronan and proteoglycan link protein 4 HAPLN4 Tbio Non-IDG -0.76903 6.57 156
Putative killer cell immunoglobulin-like receptor like protein KIR3DP1 KIR3DP1 Tdark Non-IDG 0.00000 0
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
Butyrophilin-like protein 10 BTNL10 Tdark Non-IDG 0.00000 0
Peroxidasin-like protein PXDNL Tbio Non-IDG -1.10753 14.4 0