Development Level

Tbio 324 | 10,625
Tdark 160 | 7,003
Tclin 33 | 602
Tchem 29 | 1,890

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, incomple... 9 | 260
abnormal behavior 8 | 226
decreased total body fat amoun... 7 | 186
decreased bone mineral content 6 | 157
enlarged heart 6 | 111
preweaning lethality, complete... 6 | 633
decreased grip strength 5 | 123
decreased lean body mass 5 | 195
increased or absent threshold ... 5 | 128
abnormal gait 4 | 51
abnormal seminal vesicle morph... 4 | 47
decreased body length 4 | 108
decreased bone mineral density 4 | 126
increased circulating iron lev... 4 | 25
increased circulating potassiu... 4 | 31
increased mean corpuscular hem... 4 | 93
tremors 4 | 34
abnormal sleep behavior 3 | 63
decreased circulating glucose ... 3 | 121
decreased eosinophil cell numb... 3 | 41
decreased leukocyte cell numbe... 3 | 54
hypoactivity 3 | 89
increased blood urea nitrogen ... 3 | 44
increased circulating alanine ... 3 | 11
increased exploration in new e... 3 | 56
increased mean corpuscular vol... 3 | 91
increased vertical activity 3 | 18
abnormal bone structure 2 | 131
abnormal response to new envir... 2 | 8
decreased basophil cell number 2 | 11
decreased body weight 2 | 174
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased circulating serum al... 2 | 79
decreased circulating total pr... 2 | 41
decreased circulating triglyce... 2 | 83
decreased fasted circulating g... 2 | 49
decreased prepulse inhibition 2 | 52
decreased rib number 2 | 59
enlarged epididymis 2 | 27
enlarged spleen 2 | 26
hyperactivity 2 | 108
impaired glucose tolerance 2 | 52
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased circulating calcium ... 2 | 32
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 24
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
increased leukocyte cell numbe... 2 | 37
increased rib number 2 | 41
short tibia 2 | 82
straub tail 2 | 26
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal ear morphology 1 | 5
abnormal embryo size 1 | 112
abnormal heart morphology 1 | 51
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal tail movements 1 | 12
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 21
convulsive seizures 1 | 11
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased cardiac muscle contr... 1 | 5
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating magnesiu... 1 | 11
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased pulmonary respirator... 1 | 4
dilated heart left ventricle 1 | 10
embryonic lethality prior to t... 1 | 187
impaired righting response 1 | 19
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased eosinophil cell numb... 1 | 9
increased sacral vertebrae num... 1 | 62
lethargy 1 | 5
limb grasping 1 | 35
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
thrombocytosis 1 | 23

Disease

osteosarcoma 233 | 7,933
psoriasis 226 | 6,685
ovarian cancer 191 | 8,484
medulloblastoma, large-cell 171 | 6,234
glioblastoma 161 | 5,572
lung cancer 152 | 4,466
lung carcinoma 139 | 2,844
interstitial cystitis 136 | 2,299
invasive ductal carcinoma 118 | 2,950
atypical teratoid / rhabdoid tumor 112 | 4,369
ulcerative colitis 110 | 2,087
non-small cell lung cancer 108 | 2,798
lung adenocarcinoma 106 | 2,713
pilocytic astrocytoma 103 | 3,086
Cancer 101 | 2,346
Carcinoma 98 | 2,147
Breast cancer 93 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 86 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 85 | 3,289
malignant mesothelioma 81 | 3,162
intraductal papillary-mucinous adenoma (IPMA) 80 | 2,956
oligodendroglioma 78 | 2,849
cutaneous lupus erythematosus 77 | 1,056
pediatric high grade glioma 75 | 2,712
adult high grade glioma 74 | 2,148
subependymal giant cell astrocytoma 72 | 2,287
pituitary cancer 71 | 1,972
tuberculosis 71 | 1,557
pancreatic cancer 68 | 2,300
ductal carcinoma in situ 64 | 1,745
primitive neuroectodermal tumor 63 | 3,031
group 4 medulloblastoma 61 | 1,875
ependymoma 60 | 2,514
posterior fossa group A ependymoma 60 | 1,511
cystic fibrosis 58 | 1,665
primary Sjogren syndrome 58 | 789
breast carcinoma 56 | 1,614
group 3 medulloblastoma 55 | 2,254
colon cancer 52 | 1,475
astrocytic glioma 51 | 2,241
Rheumatoid Arthritis 49 | 1,160
primary pancreatic ductal adenocarcinoma 49 | 1,271
sonic hedgehog group medulloblastoma 42 | 1,482
adrenocortical carcinoma 39 | 1,427
diabetes mellitus 39 | 1,663
astrocytoma 35 | 1,493
nasopharyngeal carcinoma 35 | 1,056
Pick disease 34 | 1,893
Multiple Sclerosis 33 | 498
mucosa-associated lymphoid tissue lymphoma 33 | 480
atypical teratoid/rhabdoid tumor 31 | 1,095
active Crohn's disease 29 | 918
gastric carcinoma 29 | 832
posterior fossa group B ependymoma 29 | 1,530
Atopic dermatitis 28 | 944
Duchenne muscular dystrophy 28 | 602
esophageal adenocarcinoma 26 | 737
non-small cell lung carcinoma 26 | 413
juvenile dermatomyositis 24 | 1,189
medulloblastoma 24 | 1,524
periodontitis 24 | 269
Down syndrome 23 | 548
Hypersensitivity reaction type II disease 23 | 235
Multiple myeloma 23 | 1,327
Asthma 22 | 349
fibroadenoma 22 | 557
chronic lymphosyte leukemia 21 | 232
head and neck cancer and chronic obstructive pulmonary disease 21 | 237
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 499
Autistic Disorder 17 | 320
Renal Cell Carcinoma 17 | 199
acute quadriplegic myopathy 17 | 1,157
aldosterone-producing adenoma 17 | 664
dermatomyositis 17 | 933
sarcoidosis 17 | 358
Alzheimer's disease 16 | 644
pancreatic carcinoma 16 | 567
spina bifida 16 | 1,064
tuberculosis and treatment for 3 months 16 | 327
tuberculosis and treatment for 6 months 16 | 686
urothelial carcinoma 16 | 318
Anemia 15 | 252
Ankylosing spondylitis 15 | 138
Endometriosis 15 | 535
IGA Glomerulonephritis 15 | 454
Kidney disease 15 | 396
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
Allergic hypersensitivity disease 14 | 123
Human immunodeficiency virus infectious disease 14 | 92
Intellectual disability 14 | 573
Mammary Neoplasms 14 | 410
Obesity 14 | 616
Schizophrenia 14 | 501
gastric cancer 14 | 430
interstitial lung disease 14 | 291
Atherosclerosis 13 | 275
acute myeloid leukemia 13 | 780
chronic rhinosinusitis 13 | 512
inflammatory breast cancer 13 | 404
progressive supranuclear palsy 13 | 674

Tissue

Digestive Tract 498 | 18,473
Female tissues 498 | 18,647
Blood and immune system 497 | 17,995
Nervous System 497 | 18,561
Endocrine System 494 | 18,512
Urinary Tract 494 | 18,444
Liver and Pancreas 492 | 18,136
Skin and soft tissues 489 | 18,115
Cardiovascular System 485 | 17,958
Respiratory system 482 | 17,484
Male tissues 478 | 17,969

Target Family

Non-IDG 496 | 11,971
Kinase 32 | 634
Enzyme 11 | 4,146
Ion Channel 4 | 341
GPCR 3 | 406

UniProt Keyword

Immunoglobulin domain 546 | 546
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
T-cell receptor beta chain V region CTL-L17 TCRB Tdark Non-IDG 0.00000 0
T-cell receptor alpha chain V region HPB-MLT N/A Tdark Non-IDG 0.00000 0
T-cell receptor alpha chain V region CTL-L17 TCRA Tdark Non-IDG 0.00000 0
T cell receptor gamma variable 3 TRGV3 Tdark Non-IDG 0.00000 0
Natural killer cell receptor 2B4 CD244 Tbio Non-IDG -2.27438 190.1 418
T-cell receptor gamma-2 chain C region TRGC2 Tdark Non-IDG 0.00000 0
Sialoadhesin SIGLEC1 Tbio Non-IDG -2.22508 195.6 309
Contactin-6 CNTN6 Tbio Non-IDG -2.02527 101.3 65
Pregnancy-specific beta-1-glycoprotein 11 PSG11 Tdark Non-IDG -0.71117 5.22 20