Development Level

Tbio 405 | 10,625
Tchem 71 | 1,890
Tdark 67 | 7,003
Tclin 28 | 602

Collection

Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 10 | 633
embryonic lethality prior to t... 8 | 187
abnormal behavior 7 | 226
decreased bone mineral content 7 | 157
decreased lean body mass 7 | 195
decreased circulating glucose ... 5 | 121
decreased grip strength 5 | 123
abnormal embryo size 4 | 112
decreased total body fat amoun... 4 | 186
embryonic lethality prior to o... 4 | 148
enlarged heart 4 | 111
increased bone mineral content 4 | 92
increased circulating HDL chol... 4 | 63
abnormal heart morphology 3 | 51
abnormal neural tube closure 3 | 37
decreased CD4-positive, CD25-p... 3 | 24
decreased body weight 3 | 174
decreased neutrophil cell numb... 3 | 37
hyperactivity 3 | 108
increased circulating choleste... 3 | 53
increased circulating sodium l... 3 | 71
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
small superior vagus ganglion 3 | 20
abnormal behavioral response t... 2 | 52
abnormal bone structure 2 | 131
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal tail movements 2 | 12
abnormal testis morphology 2 | 30
decreased B cell number 2 | 30
decreased CD8-positive, alpha-... 2 | 26
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
decreased monocyte cell number 2 | 28
decreased prepulse inhibition 2 | 52
female infertility 2 | 34
hypoactivity 2 | 89
increased NK cell number 2 | 19
increased bone mineral density 2 | 52
increased circulating alanine ... 2 | 11
increased circulating calcium ... 2 | 32
increased circulating potassiu... 2 | 31
increased circulating total pr... 2 | 20
increased erythrocyte cell num... 2 | 26
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
small testis 2 | 37
thrombocytopenia 2 | 46
abnormal embryo turning 1 | 15
abnormal femur morphology 1 | 14
abnormal hair growth 1 | 8
abnormal heart looping 1 | 2
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal neural tube morpholog... 1 | 8
abnormal pelvic girdle bone mo... 1 | 11
abnormal skin morphology 1 | 23
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 35
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased heart rate 1 | 10
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased mature B cell number 1 | 25
decreased rib number 1 | 59
embryonic growth retardation 1 | 28
enlarged adrenal glands 1 | 3
enlarged lymph nodes 1 | 27
hydrometra 1 | 13
increased body length 1 | 20
increased body weight 1 | 42
increased circulating aspartat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 37
increased mean platelet volume 1 | 19
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
oligodactyly 1 | 14
pallor 1 | 13
prolonged RR interval 1 | 2
shortened PQ interval 1 | 6
tremors 1 | 34

Disease

psoriasis 256 | 6,685
ovarian cancer 229 | 8,484
osteosarcoma 226 | 7,933
lung cancer 204 | 4,466
Cancer 189 | 2,346
lung carcinoma 184 | 2,844
glioblastoma 160 | 5,572
interstitial cystitis 153 | 2,299
ulcerative colitis 140 | 2,087
medulloblastoma, large-cell 137 | 6,234
cutaneous lupus erythematosus 128 | 1,056
tuberculosis 122 | 1,557
diabetes mellitus 120 | 1,663
non-small cell lung cancer 116 | 2,798
Rheumatoid Arthritis 114 | 1,160
pilocytic astrocytoma 113 | 3,086
subependymal giant cell astrocytoma 109 | 2,287
primary Sjogren syndrome 106 | 789
invasive ductal carcinoma 103 | 2,950
malignant mesothelioma 102 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 96 | 3,289
lung adenocarcinoma 91 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 90 | 2,988
Hypersensitivity reaction type II disease 86 | 235
intraductal papillary-mucinous adenoma (IPMA) 86 | 2,956
pancreatic cancer 84 | 2,300
Multiple Sclerosis 83 | 498
juvenile dermatomyositis 83 | 1,189
Arthritis 81 | 248
Ankylosing spondylitis 79 | 138
cystic fibrosis 73 | 1,665
astrocytoma 69 | 1,493
Acquired immunodeficiency syndrome 66 | 164
Juvenile rheumatoid arthritis 66 | 104
dermatomyositis 66 | 933
active Crohn's disease 65 | 918
pediatric high grade glioma 65 | 2,712
adult high grade glioma 64 | 2,148
Breast cancer 62 | 3,094
Uveitis 61 | 103
atypical teratoid / rhabdoid tumor 61 | 4,369
Behcet's disease 60 | 74
Psoriatic arthritis 56 | 83
group 4 medulloblastoma 55 | 1,875
posterior fossa group A ependymoma 55 | 1,511
pancreatic ductal adenocarcinoma liver metastasis 54 | 1,795
pituitary cancer 51 | 1,972
Kidney disease 48 | 396
primary pancreatic ductal adenocarcinoma 48 | 1,271
breast carcinoma 47 | 1,614
Carcinoma 46 | 2,147
adrenocortical carcinoma 45 | 1,427
Multiple myeloma 44 | 1,327
esophageal adenocarcinoma 44 | 737
mucosa-associated lymphoid tissue lymphoma 44 | 480
oligodendroglioma 44 | 2,849
systemic lupus erythematosus 44 | 156
group 3 medulloblastoma 43 | 2,254
Stevens-Johnson syndrome 40 | 78
Duchenne muscular dystrophy 38 | 602
Influenza 38 | 142
Takayasu's arteritis 38 | 52
colon cancer 38 | 1,475
ductal carcinoma in situ 38 | 1,745
Atopic dermatitis 37 | 944
Congenital adrenal hyperplasia 37 | 74
chronic lymphosyte leukemia 37 | 232
head and neck cancer and chronic obstructive pulmonary disease 37 | 237
Anemia 36 | 252
Liver disease 36 | 219
gastric carcinoma 36 | 832
Hepatitis B 35 | 103
Leprosy 35 | 77
Retinal vasculitis 35 | 36
nasopharyngeal carcinoma 35 | 1,056
IGA Glomerulonephritis 34 | 454
ependymoma 31 | 2,514
primitive neuroectodermal tumor 31 | 3,031
Lupus erythematosus 30 | 80
Human immunodeficiency virus infectious disease 29 | 92
Asthma 28 | 349
Waldenstrons macroglobulinemia 28 | 765
acute myeloid leukemia 28 | 780
periodontitis 28 | 269
acute quadriplegic myopathy 27 | 1,157
astrocytic glioma 27 | 2,241
sarcoidosis 27 | 358
Crohn's disease 25 | 304
Hemochromatosis 24 | 55
Pick disease 24 | 1,893
Primary immunodeficiency disease 24 | 52
Skin disease 24 | 65
hepatocellular carcinoma 24 | 532
pancreatic carcinoma 23 | 567
Down syndrome 22 | 548
gastric cancer 21 | 430
medulloblastoma 21 | 1,524
posterior fossa group B ependymoma 21 | 1,530
aldosterone-producing adenoma 20 | 664
spina bifida 20 | 1,064

Tissue

Female tissues 485 | 18,647
Blood and immune system 484 | 17,995
Digestive Tract 483 | 18,473
Urinary Tract 483 | 18,444
Nervous System 481 | 18,561
Liver and Pancreas 478 | 18,136
Endocrine System 477 | 18,512
Cardiovascular System 475 | 17,958
Respiratory system 475 | 17,484
Skin and soft tissues 470 | 18,115
Male tissues 467 | 17,969

Target Family

Non-IDG 435 | 11,971
Enzyme 73 | 4,146
Kinase 35 | 634
Transcription Factor 15 | 1,400
GPCR 7 | 406
Ion Channel 3 | 341
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Immunity 571 | 571
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
HLA class II histocompatibility antigen, DRB1-14 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 337
Antileukoproteinase SLPI Tbio Enzyme -2.56514 434.2 290
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
HLA class I histocompatibility antigen, Cw-5 alpha chain HLA-C Tbio Non-IDG 777.4 0