Development Level

Tbio 465 | 11,445
Tdark 149 | 6,588
Tchem 72 | 1,598
Tclin 31 | 613

Collection

GPCR: IDG Consortium (Complete... 2 | 25
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 18 | 979
abnormal behavior 13 | 298
embryonic lethality prior to t... 9 | 278
decreased bone mineral content 7 | 151
decreased mean corpuscular vol... 7 | 79
abnormal embryo size 6 | 220
decreased lean body mass 6 | 135
decreased vertical activity 6 | 208
abnormal bone structure 5 | 187
decreased circulating choleste... 5 | 93
decreased circulating glucose ... 5 | 126
decreased grip strength 5 | 116
embryonic lethality prior to o... 5 | 239
hypoactivity 5 | 132
increased lean body mass 5 | 172
abnormal heart morphology 4 | 162
decreased blood urea nitrogen ... 4 | 51
decreased lymphocyte cell numb... 4 | 83
decreased total body fat amoun... 4 | 207
embryonic growth retardation 4 | 106
enlarged heart 4 | 210
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
preweaning lethality, incomple... 4 | 499
small superior vagus ganglion 4 | 74
abnormal neural tube closure 3 | 46
abnormal seminal vesicle morph... 3 | 114
cardiovascular system phenotyp... 3 | 36
decreased circulating HDL chol... 3 | 68
decreased heart weight 3 | 27
decreased leukocyte cell numbe... 3 | 73
hyperactivity 3 | 148
increased circulating sodium l... 3 | 71
increased erythrocyte cell num... 3 | 39
increased hematocrit 3 | 46
increased mean corpuscular vol... 3 | 92
increased neutrophil cell numb... 3 | 46
thrombocytopenia 3 | 56
abnormal behavioral response t... 2 | 66
abnormal gait 2 | 69
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
abnormal testis morphology 2 | 43
decreased CD8-positive, alpha-... 2 | 8
decreased T cell number 2 | 15
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating iron lev... 2 | 32
decreased circulating phosphat... 2 | 27
decreased circulating potassiu... 2 | 20
decreased circulating triglyce... 2 | 79
decreased mean corpuscular hem... 2 | 50
enlarged lymph nodes 2 | 37
female infertility 2 | 60
hydrometra 2 | 53
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating alanine ... 2 | 13
increased circulating potassiu... 2 | 29
increased eosinophil cell numb... 2 | 11
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased monocyte cell number 2 | 63
male infertility 2 | 123
prolonged QRS complex duration 2 | 8
small testis 2 | 58
abnormal embryo turning 1 | 31
abnormal hair growth 1 | 10
abnormal heart looping 1 | 5
abnormal lung morphology 1 | 26
abnormal neural tube morpholog... 1 | 12
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
decreased body length 1 | 101
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
impaired righting response 1 | 26
increased aggression 1 | 4
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased red blood cell distr... 1 | 34
tremors 1 | 39

Disease

Carcinoma 334 | 11,493
psoriasis 296 | 6,694
osteosarcoma 267 | 7,950
ovarian cancer 253 | 8,520
lung cancer 224 | 4,740
Cancer 210 | 2,499
lung carcinoma 192 | 2,843
glioblastoma 185 | 5,792
tuberculosis 175 | 2,010
interstitial cystitis 174 | 2,312
medulloblastoma, large-cell 152 | 6,241
cutaneous lupus erythematosus 135 | 1,057
diabetes mellitus 133 | 1,728
ulcerative colitis 130 | 1,819
non-small cell lung cancer 129 | 2,890
Rheumatoid arthritis 128 | 1,191
adult high grade glioma 119 | 3,801
Astrocytoma, Pilocytic 118 | 3,081
malignant mesothelioma 116 | 3,232
subependymal giant cell astrocytoma 113 | 2,287
invasive ductal carcinoma 112 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 107 | 3,291
primary Sjogren syndrome 107 | 735
lung adenocarcinoma 104 | 2,716
dermatomyositis 101 | 966
ependymoma 97 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 95 | 2,989
Hypersensitivity reaction type II disease 93 | 253
pancreatic cancer 93 | 2,398
Arthritis 92 | 290
intraductal papillary-mucinous adenoma (IPMA) 92 | 2,955
Breast cancer 88 | 3,578
juvenile dermatomyositis 88 | 1,187
Multiple Sclerosis 86 | 540
atypical teratoid / rhabdoid tumor 82 | 5,112
Ankylosing spondylitis 80 | 140
cystic fibrosis 80 | 1,696
Behcet's disease 75 | 89
group 3 medulloblastoma 73 | 4,104
active Crohn's disease 70 | 922
Juvenile rheumatoid arthritis 69 | 111
pancreatic ductal adenocarcinoma liver metastasis 69 | 1,962
Acquired immunodeficiency syndrome 67 | 197
Systemic lupus erythematosus 67 | 194
Human immunodeficiency virus infectious disease 66 | 138
astrocytoma 65 | 1,146
Kidney cancer 64 | 2,613
Uveitis 63 | 103
Herpes zoster 59 | 68
Autosomal recessive predisposition 57 | 1,442
Psoriatic arthritis 57 | 86
Multiple myeloma 56 | 1,332
group 4 medulloblastoma 56 | 1,855
oligodendroglioma 54 | 2,850
Dermatitis 53 | 157
Stevens-Johnson syndrome 53 | 92
Kidney disease 52 | 430
pituitary cancer 52 | 1,972
breast carcinoma 51 | 1,638
Schizophrenia 50 | 1,160
adrenocortical carcinoma 49 | 1,428
mucosa-associated lymphoid tissue lymphoma 49 | 484
esophageal adenocarcinoma 47 | 737
Liver Cirrhosis, Experimental 46 | 769
colon cancer 46 | 1,478
active ulcerative colitis 45 | 764
astrocytic glioma 45 | 2,597
ductal carcinoma in situ 42 | 1,745
Behcet's syndrome 41 | 50
periodontitis 41 | 293
Anemia 40 | 365
Atopic dermatitis 40 | 952
Liver disease 40 | 237
nasopharyngeal carcinoma 40 | 1,058
primary pancreatic ductal adenocarcinoma 40 | 1,109
Duchenne muscular dystrophy 39 | 601
Influenza 39 | 142
chronic lymphosyte leukemia 39 | 204
head and neck cancer and chronic obstructive pulmonary disease 39 | 239
Hepatitis B 38 | 108
Nephritis 38 | 51
Takayasu's arteritis 38 | 53
primitive neuroectodermal tumor 38 | 3,035
sarcoidosis 38 | 370
Congenital adrenal hyperplasia 37 | 73
Melanoma 36 | 711
Synovitis 36 | 78
drug-induced hepatitis 36 | 44
Asthma 35 | 385
Leprosy 35 | 73
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
gastric carcinoma 35 | 807
Waldenstrons macroglobulinemia 32 | 765
acute myeloid leukemia 32 | 783
acute quadriplegic myopathy 32 | 1,158
Immunologic Deficiency Syndromes 31 | 113
Crohn's disease 30 | 321
Pick disease 27 | 1,894
Bipolar Disorder 25 | 666

Tissue

Blood and immune system 471 | 16,909
Digestive Tract 469 | 17,369
Female tissues 467 | 17,400
Liver and Pancreas 466 | 16,750
Skin and soft tissues 466 | 17,230
Endocrine System 465 | 18,159
Respiratory system 460 | 16,393
Urinary Tract 460 | 16,678
Male tissues 452 | 17,142
Nervous System 429 | 16,725
Cardiovascular System 424 | 15,192

Target Family

Non-IDG 564 | 12,091
Enzyme 83 | 4,145
Kinase 37 | 634
Transcription Factor 16 | 1,400
GPCR 8 | 408
Ion Channel 5 | 344
Epigenetic 2 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

UniProt Keyword

Immunity 717 | 717
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
Spondin-2 SPON2 Tbio Non-IDG -1.73555 56.2 210
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.43609 25.1 193
Immunoglobulin heavy variable 1-69D IGHV1-69D Tdark Non-IDG 0.00000 0
Tumor necrosis factor receptor superfamily member 13C TNFRSF13C Tbio Non-IDG -2.48953 288.2 437
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333