Development Level

Tbio 23 | 11,445
Tchem 3 | 1,598

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
embryonic growth retardation 1 | 106
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased or absent threshold ... 1 | 101
increased total retina thickne... 1 | 4
male infertility 1 | 123
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Hypotrichosis 26 | 47
Carcinoma 21 | 11,493
ovarian cancer 13 | 8,520
psoriasis 12 | 6,694
Breast cancer 11 | 3,578
osteosarcoma 11 | 7,950
Alopecia 9 | 115
Autosomal recessive predisposition 9 | 1,442
malignant mesothelioma 8 | 3,232
Cancer 7 | 2,499
lung cancer 7 | 4,740
medulloblastoma, large-cell 7 | 6,241
pancreatic cancer 7 | 2,398
Epilepsy 6 | 792
Hypotrichosis simplex 6 | 7
Intellectual disability 6 | 1,016
Sparse eyebrow 6 | 42
Sparse eyelashes 6 | 31
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
Brittle hair 5 | 25
Fractured hair 5 | 25
Fragile hair 5 | 25
Monilethrix 5 | 18
Reduced tensile strength of hair 5 | 25
Sparse body hair 5 | 32
Woolly hair, autosomal dominant 5 | 5
Woolly hair, congenital 5 | 5
Wooly hair 5 | 17
breast carcinoma 5 | 1,638
ependymoma 5 | 4,679
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Dental abnormalities 4 | 60
Fine hair 4 | 42
Hypotrichosis of the scalp 4 | 6
Kidney cancer 4 | 2,613
Netherton syndrome 4 | 15
Peeling skin syndrome 4 | 17
Seizures 4 | 596
Short stature 4 | 531
Small head 4 | 374
Sparse scalp hair 4 | 42
Tooth Abnormalities 4 | 69
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
Absent eyebrow 3 | 13
Asthma 3 | 385
Big calvaria 3 | 147
Broad flat nasal bridge 3 | 236
Class III malocclusion 3 | 78
Coffin-Siris syndrome 3 | 17
Cognitive delay 3 | 608
Dental caries 3 | 164
Dull intelligence 3 | 645
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
Hypertrophy of lower jaw 3 | 78
Hypotrichosis 6 3 | 4
Hypotrichosis 8 3 | 6
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of mandible 3 | 78
Increased size of skull 3 | 147
Low intelligence 3 | 645
Madarosis of eyebrow 3 | 13
Mandibular hyperplasia 3 | 78
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Nail Diseases 3 | 24
Nail abnormality 3 | 22
Nasal bridge wide 3 | 236
Palmoplantar keratosis 3 | 74
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Prostatic Neoplasms 3 | 495
Recurrent respiratory infections 3 | 141
Skin cancer 3 | 469
Sparse hair 3 | 59
Thin, sparse hair 3 | 59
adult high grade glioma 3 | 3,801
atypical teratoid/rhabdoid tumor 3 | 357
esophageal adenocarcinoma 3 | 737
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
lung carcinoma 3 | 2,843
mandibular excess (physical finding) 3 | 78
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Skin and soft tissues 23 | 17,230
Male tissues 22 | 17,142
Digestive Tract 21 | 17,369
Blood and immune system 20 | 16,909
Nervous System 20 | 16,725
Urinary Tract 20 | 16,678
Liver and Pancreas 19 | 16,750
Respiratory system 19 | 16,393
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 3 | 4,145
Epigenetic 2 | 242
GPCR 1 | 408
Transcription Factor 1 | 1,400

UniProt Keyword

Hypotrichosis 26 | 26
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
PHD finger protein 6 PHF6 Tbio Epigenetic -1.79561 64.2 134
Lysine-specific demethylase hairless HR Tbio Enzyme -1.13301 12.4 99
Keratin, type II cytoskeletal 74 KRT74 Tbio Non-IDG -2.24212 165.9 40
Corneodesmosin CDSN Tbio Non-IDG -3.23661 1709.5 0
Protein Wnt-10a WNT10A Tbio Non-IDG -2.66153 436.3 118
Cadherin-3 CDH3 Tbio Non-IDG -2.41963 266.8 538
Keratin, type I cytoskeletal 25 KRT25 Tbio Non-IDG -0.59195 2.65 85
Transcription factor SOX-18 SOX18 Tbio Transcription Factor -1.82305 69.9 128
Keratin, type II cytoskeletal 71 KRT71 Tbio Non-IDG -0.88301 7.82 64