Development Level

Tbio 35 | 11,178
Tdark 7 | 6,569
Tchem 4 | 1,885
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 5 | 278
abnormal behavior 2 | 298
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased heart rate variabili... 1 | 7
increased or absent threshold ... 1 | 101
narrow eye opening 1 | 12
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

ovarian cancer 25 | 8,297
Carcinoma 21 | 11,192
Multiple myeloma 15 | 1,296
osteosarcoma 15 | 7,766
psoriasis 14 | 6,514
astrocytic glioma 12 | 2,530
glioblastoma 11 | 5,635
lung cancer 11 | 4,607
medulloblastoma, large-cell 11 | 6,086
oligodendroglioma 11 | 2,768
atypical teratoid / rhabdoid tumor 10 | 4,971
ependymoma 10 | 4,559
Pick disease 9 | 1,856
Osteopetrosis 7 | 42
Waldenstrons macroglobulinemia 7 | 742
diabetes mellitus 7 | 1,683
lung carcinoma 7 | 2,755
primitive neuroectodermal tumor 7 | 2,957
Autosomal recessive predisposition 6 | 1,407
Breast cancer 6 | 3,469
adult high grade glioma 6 | 3,701
group 3 medulloblastoma 6 | 4,002
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,911
Astrocytoma, Pilocytic 5 | 3,006
Epilepsy 5 | 775
Pneumonia 5 | 169
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,204
subependymal giant cell astrocytoma 5 | 2,230
3-methylglutaconic aciduria 4 | 29
Anemia 4 | 353
Cutis Laxa 4 | 39
Failure to gain weight 4 | 359
Kidney cancer 4 | 2,548
Parkinson's disease 4 | 378
Pediatric failure to thrive 4 | 359
Seizures 4 | 584
breast carcinoma 4 | 1,589
pancreatic cancer 4 | 2,322
Alzheimer's disease 3 | 640
Dementia 3 | 172
Gastritis 3 | 44
Gastroesophageal reflux disease 3 | 108
Kidney disease 3 | 411
Leigh disease 3 | 100
Muscle hypotonia 3 | 562
Neuronal ceroid lipofuscinosis 3 | 28
Nystagmus 3 | 309
Osteoporosis 3 | 348
Spindle cell hemangioma 3 | 16
Zollinger-Ellison syndrome 3 | 18
astrocytoma 3 | 1,113
cystic fibrosis 3 | 1,629
dermatomyositis 3 | 941
group 4 medulloblastoma 3 | 1,806
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,872
invasive ductal carcinoma 3 | 2,867
malignant mesothelioma 3 | 3,135
pituitary cancer 3 | 1,915
tuberculosis 3 | 1,963
Achalasia 2 | 13
Atrial Fibrillation 2 | 120
Barrett's esophagus 2 | 173
Blind Vision 2 | 110
Blindness, Legal 2 | 109
Cardiomyopathy 2 | 116
Cerebrovascular disease 2 | 223
Chronic intestinal vascular insufficiency 2 | 12
Congenital deafness 2 | 180
Constipation 2 | 174
Coronary artery disease 2 | 253
Deafness 2 | 193
Dental caries 2 | 157
Diarrhea 2 | 245
Dyspepsia 2 | 32
Frontal bossing 2 | 154
Gaucher disease type 1 2 | 177
Growth delay 2 | 112
Growth failure 2 | 112
Growth retardation 2 | 113
Hearing Loss, Partial 2 | 180
Inflammatory bowel disease 2 | 148
Irritable bowel syndrome 2 | 57
Late tooth eruption 2 | 59
Liver disease 2 | 227
Lymphoma, Follicular 2 | 18
Nasal bridge wide 2 | 232
Nephrocalcinosis 2 | 34
Neuropathy 2 | 254
Pain disorder 2 | 15
Peripheral Neuropathy 2 | 131
Peritonitis 2 | 42
Poor growth 2 | 112
Prenatal onset 2 | 137
Sensorineural Hearing Loss (disorder) 2 | 281
Sensorineural hearing loss 2 | 102
Very poor growth 2 | 112
Vitamin B12 deficiency 2 | 20
hearing impairment 2 | 194
medulloblastoma 2 | 702
tuberculosis and treatment for 6 months 2 | 399

Tissue

Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Male tissues 47 | 17,142
Urinary Tract 47 | 16,678
Endocrine System 46 | 18,159
Female tissues 45 | 17,400
Nervous System 45 | 16,725
Skin and soft tissues 45 | 17,230
Respiratory system 44 | 16,393
Liver and Pancreas 43 | 16,750
Cardiovascular System 41 | 15,192

Target Family

Enzyme 44 | 4,145
Transporter 4 | 473

UniProt Keyword

Hydrogen ion transport 48 | 48
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP synthase subunit e, mitochondrial ATP5ME Tbio Enzyme -0.44902 2.34 100
ATP synthase subunit epsilon, mitochondrial ATP5F1E Tbio Enzyme -1.86682 69.6 105
V-type proton ATPase subunit F ATP6V1F Tbio Enzyme -0.91914 8.76 118
ATP synthase F(0) complex subunit C1, mitochondrial ATP5MC1 Tbio Enzyme -1.19949 13.4 100
V-type proton ATPase subunit S1 ATP6AP1 Tchem Enzyme -1.94689 91.3 166
V-type proton ATPase 21 kDa proteolipid subunit ATP6V0B Tbio Enzyme -0.96261 10.7 81
V-type proton ATPase subunit G 2 ATP6V1G2 Tbio Enzyme -0.88393 7.05 52
ATP synthase subunit s, mitochondrial ATP5S Tdark Enzyme -0.41218 1.48 122
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Sodium/hydrogen exchanger 9B2 SLC9B2 Tbio Transporter -1.21956 18.8 126