Development Level

Tbio 36 | 11,651
Tdark 7 | 6,593
Tchem 3 | 1,388
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 5 | 278
abnormal behavior 2 | 298
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased heart rate variabili... 1 | 7
increased or absent threshold ... 1 | 101
narrow eye opening 1 | 12
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

ovarian cancer 25 | 8,520
Carcinoma 21 | 11,493
Multiple myeloma 15 | 1,332
osteosarcoma 15 | 7,950
psoriasis 14 | 6,694
astrocytic glioma 12 | 2,597
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
medulloblastoma, large-cell 11 | 6,241
oligodendroglioma 11 | 2,850
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
Pick disease 9 | 1,894
Osteopetrosis 7 | 43
Waldenstrons macroglobulinemia 7 | 765
diabetes mellitus 7 | 1,728
lung carcinoma 7 | 2,843
primitive neuroectodermal tumor 7 | 3,035
Autosomal recessive predisposition 6 | 1,442
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Astrocytoma, Pilocytic 5 | 3,081
Epilepsy 5 | 792
Pneumonia 5 | 174
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
subependymal giant cell astrocytoma 5 | 2,287
3-methylglutaconic aciduria 4 | 29
Anemia 4 | 365
Cutis Laxa 4 | 39
Failure to gain weight 4 | 365
Kidney cancer 4 | 2,613
Parkinson's disease 4 | 392
Pediatric failure to thrive 4 | 365
Seizures 4 | 596
breast carcinoma 4 | 1,638
pancreatic cancer 4 | 2,398
Alzheimer's disease 3 | 658
Dementia 3 | 175
Gastritis 3 | 47
Gastroesophageal reflux disease 3 | 110
Kidney disease 3 | 430
Leigh disease 3 | 100
Muscle hypotonia 3 | 571
Neuronal ceroid lipofuscinosis 3 | 28
Nystagmus 3 | 317
Osteoporosis 3 | 363
Spindle cell hemangioma 3 | 16
Zollinger-Ellison syndrome 3 | 18
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Achalasia 2 | 13
Atrial Fibrillation 2 | 124
Barrett's esophagus 2 | 182
Blind Vision 2 | 111
Blindness, Legal 2 | 110
Candidiasis 2 | 55
Cardiomyopathy 2 | 116
Cerebrovascular disease 2 | 238
Chronic intestinal vascular insufficiency 2 | 12
Congenital deafness 2 | 185
Constipation 2 | 181
Coronary artery disease 2 | 268
Deafness 2 | 198
Dental caries 2 | 164
Diarrhea 2 | 253
Dyspepsia 2 | 33
Frontal bossing 2 | 157
Gaucher disease type 1 2 | 180
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hearing Loss, Partial 2 | 185
Inflammatory bowel disease 2 | 151
Irritable bowel syndrome 2 | 60
Late tooth eruption 2 | 61
Liver disease 2 | 237
Lymphoma, Follicular 2 | 18
Nasal bridge wide 2 | 236
Nephrocalcinosis 2 | 35
Neuropathy 2 | 261
Pain disorder 2 | 15
Peritonitis 2 | 43
Poor growth 2 | 114
Prenatal onset 2 | 139
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Very poor growth 2 | 114
Vitamin B12 deficiency 2 | 20
hearing impairment 2 | 199
medulloblastoma 2 | 720
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Male tissues 47 | 17,142
Urinary Tract 47 | 16,678
Endocrine System 46 | 18,159
Female tissues 45 | 17,400
Nervous System 45 | 16,725
Skin and soft tissues 45 | 17,230
Respiratory system 44 | 16,393
Liver and Pancreas 43 | 16,750
Cardiovascular System 41 | 15,192

Target Family

Enzyme 44 | 4,145
Transporter 4 | 473

UniProt Keyword

Hydrogen ion transport 48 | 48
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V-type proton ATPase subunit B, kidney isoform ATP6V1B1 Tchem Enzyme -1.71459 43.7 251
V-type proton ATPase subunit D ATP6V1D Tbio Enzyme -1.48812 30.2 69
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
V-type proton ATPase 16 kDa proteolipid subunit ATP6V0C Tbio Enzyme -1.87899 78.9 72
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.40105 25.1 63
ATP synthase F(0) complex subunit C3, mitochondrial ATP5MC3 Tdark Enzyme -1.13820 13.2 31
V-type proton ATPase subunit d 2 ATP6V0D2 Tbio Enzyme -1.17065 12.0 74
V-type proton ATPase 116 kDa subunit a isoform 3 TCIRG1 Tbio Enzyme -1.92345 93.5 63
V-type proton ATPase subunit H ATP6V1H Tbio Enzyme -1.26664 18.3 119
Potassium-transporting ATPase alpha chain 2 ATP12A Tchem Transporter -3.82877 6449.5 90