Development Level

Tbio 42 | 11,445
Tchem 17 | 1,598
Tclin 10 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased total body fat amoun... 3 | 207
preweaning lethality, incomple... 3 | 499
decreased body weight 2 | 161
enlarged lymph nodes 2 | 37
increased circulating choleste... 2 | 66
increased leukocyte cell numbe... 2 | 47
preweaning lethality, complete... 2 | 979
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal hair texture 1 | 4
abnormal incisor color 1 | 3
abnormal incisor morphology 1 | 4
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal sensory capabilities-... 1 | 8
abnormal social-conspecific in... 1 | 3
abnormal spine curvature 1 | 9
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating unsatura... 1 | 2
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged spleen 1 | 41
eyelids fail to open 1 | 3
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
kyphosis 1 | 5
long tibia 1 | 25
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small adrenal glands 1 | 16
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 49 | 11,493
Cancer 40 | 2,499
osteosarcoma 37 | 7,950
ovarian cancer 36 | 8,520
glioblastoma 31 | 5,792
interstitial cystitis 29 | 2,312
atypical teratoid / rhabdoid tumor 28 | 5,112
lung cancer 28 | 4,740
psoriasis 28 | 6,694
lung carcinoma 26 | 2,843
invasive ductal carcinoma 24 | 2,951
medulloblastoma, large-cell 24 | 6,241
Breast cancer 21 | 3,578
non-small cell lung cancer 21 | 2,890
ependymoma 20 | 4,679
malignant mesothelioma 20 | 3,232
pancreatic cancer 20 | 2,398
Astrocytoma, Pilocytic 19 | 3,081
adult high grade glioma 19 | 3,801
ductal carcinoma in situ 19 | 1,745
group 3 medulloblastoma 19 | 4,104
ulcerative colitis 19 | 1,819
lung adenocarcinoma 18 | 2,716
tuberculosis 18 | 2,010
diabetes mellitus 16 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
oligodendroglioma 15 | 2,850
Rheumatoid arthritis 14 | 1,191
cutaneous lupus erythematosus 14 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
primitive neuroectodermal tumor 14 | 3,035
Autosomal recessive predisposition 13 | 1,442
Kidney cancer 13 | 2,613
Multiple Sclerosis 13 | 540
Schizophrenia 13 | 1,160
Human immunodeficiency virus infectious disease 11 | 138
Hypersensitivity reaction type II disease 11 | 253
colon cancer 11 | 1,478
primary pancreatic ductal adenocarcinoma 11 | 1,109
Anemia 10 | 365
Atherosclerosis 10 | 291
breast carcinoma 10 | 1,638
nasopharyngeal carcinoma 10 | 1,058
subependymal giant cell astrocytoma 10 | 2,287
Down syndrome 9 | 499
Liver Cirrhosis, Experimental 9 | 769
astrocytic glioma 9 | 2,597
astrocytoma 9 | 1,146
cystic fibrosis 9 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary Sjogren syndrome 9 | 735
Atopic dermatitis 8 | 952
Kidney disease 8 | 430
Thrombocytopenia 8 | 197
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,158
dermatomyositis 8 | 966
gastric carcinoma 8 | 807
spina bifida 8 | 1,074
Alzheimer's disease 7 | 658
Endometriosis 7 | 540
Liver disease 7 | 237
Malaria 7 | 160
Neoplasm Invasiveness 7 | 161
Obesity 7 | 678
adrenocortical carcinoma 7 | 1,428
non-small cell lung carcinoma 7 | 317
pituitary cancer 7 | 1,972
sarcoidosis 7 | 370
Asthma 6 | 385
Cerebrovascular disease 6 | 238
Coronary artery disease 6 | 268
Dementia 6 | 175
Duchenne muscular dystrophy 6 | 601
Hepatomegaly 6 | 285
Lung disease 6 | 142
Multiple myeloma 6 | 1,332
Pick disease 6 | 1,894
Splenomegaly 6 | 190
Vascular disease 6 | 319
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,187
pediatric high grade glioma 6 | 1,064
Arthritis 5 | 290
Breast Neoplasms 5 | 445
Crohn's disease 5 | 321
Epilepsy 5 | 792
Major Depressive Disorder 5 | 301
Mammary Neoplasms 5 | 425
Prostatic Neoplasms 5 | 495
Systemic lupus erythematosus 5 | 194
Type 2 diabetes mellitus 5 | 272
Unipolar Depression 5 | 250
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
group 4 medulloblastoma 5 | 1,855
interstitial lung disease 5 | 298
mucosa-associated lymphoid tissue lymphoma 5 | 484
nephrosclerosis 5 | 333
progressive supranuclear palsy 5 | 676

Tissue

Blood and immune system 69 | 16,909
Endocrine System 69 | 18,159
Female tissues 69 | 17,400
Digestive Tract 68 | 17,369
Liver and Pancreas 68 | 16,750
Nervous System 68 | 16,725
Respiratory system 68 | 16,393
Skin and soft tissues 68 | 17,230
Urinary Tract 68 | 16,678
Male tissues 67 | 17,142
Cardiovascular System 62 | 15,192

Target Family

Non-IDG 53 | 12,091
Kinase 5 | 634
Transporter 5 | 473
Enzyme 4 | 4,145
GPCR 3 | 408

UniProt Keyword

Host cell receptor for virus e... 70 | 70
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Sodium/bile acid cotransporter SLC10A1 Tchem Transporter -2.69150 476.1 163
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Cadherin-related family member 3 CDHR3 Tdark Non-IDG -1.12856 13.9 46