Development Level

Tbio 7 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased startle reflex 1 | 75
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Visceral heterotaxy 9 | 14
Situs ambiguous 8 | 8
Situs ambiguus 8 | 25
Carcinoma 7 | 11,493
Right atrial isomerism 7 | 29
Situs Inversus 6 | 65
Congenital heart disease 3 | 93
Dextrocardia 3 | 12
Heterotaxy Syndrome 3 | 5
Primary ciliary dyskinesia 3 | 76
Ventricular Septal Defects 3 | 119
group 3 medulloblastoma 3 | 4,104
ovarian cancer 3 | 8,520
ATRIOVENTRICULAR CANAL DEFECT 2 | 17
Atrial Septal Defects 2 | 85
Cleft Palate 2 | 271
Discordant ventriculoarterial connection 2 | 17
Endocardial Cushion Defects 2 | 17
Hydrocephalus 2 | 152
ependymoma 2 | 4,679
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
nasopharyngeal carcinoma 2 | 1,058
osteosarcoma 2 | 7,950
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
Abnormal vertebral bodies 1 | 16
Abnormalities, Multiple 1 | 13
Abnormality of the respiratory system 1 | 4
Absence of radius and ulna 1 | 15
Absent radius 1 | 15
Alobar Holoprosencephaly 1 | 14
Appendicitis 1 | 15
Astigmatism 1 | 54
Autosomal dominant polycystic kidney disease 1 | 31
Biliary atresia 1 | 12
Biliary atresia with splenic malformation syndrome 1 | 1
Bone Diseases, Developmental 1 | 27
Bronchiectasis 1 | 64
CONOTRUNCAL HEART MALFORMATIONS (disorder) 1 | 6
Cardiomegaly 1 | 116
Cholecystitis 1 | 18
Cholelithiasis 1 | 33
Chromosome 18p deletion syndrome 1 | 5
Clubfoot 1 | 39
Congenital anomaly of spine 1 | 16
Congenital atresia of mitral valve 1 | 2
Conotruncal Heart Malformations 1 | 10
Craniofacial Abnormalities 1 | 151
Cystic lymphangioma 1 | 19
Dermatologic disorders 1 | 93
DiGeorge syndrome 1 | 47
Double Outlet Right Ventricle 1 | 11
Ectopic spleen 1 | 1
Enlarged kidney 1 | 14
Esophageal atresia 1 | 43
Facial asymmetry 1 | 32
HETEROTAXY, VISCERAL, 4, AUTOSOMAL 1 | 1
Hand polydactyly 1 | 11
Heterotaxy, Visceral, 2, Autosomal 1 | 2
Heterotaxy, Visceral, 5, Autosomal 1 | 1
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Holoprosencephaly 1 | 56
Hydronephrosis 1 | 89
Imperforate anus 1 | 25
Infertility 1 | 188
Intestinal Obstruction 1 | 31
Liver cancer 1 | 604
Lymphoproliferative syndrome 1 | 58
Melanoma 1 | 711
Microcephaly 1 | 166
Microphthalmia 1 | 76
Multiple synostoses syndrome 1 | 9
Multiple vertebral anomalies 1 | 16
Neurohypophyseal diabetes insipidus 1 | 13
Parovarian cyst 1 | 1
Patau syndrome 1 | 14
Phenotypic variability 1 | 150
Polysplenia 1 | 7
Proximally placed thumbs 1 | 17
Pulmonary Stenosis 1 | 45
Radial aplasia 1 | 15
Right aortic arch (disorder) 1 | 1
Scoliosis 1 | 44
Semilobar Holoprosencephaly 1 | 14
Septooptic dysplasia 1 | 19
Short upper arms 1 | 16
Sinusitis 1 | 65
Skin Diseases 1 | 71
Skin cancer 1 | 469
Tracheoesophageal Fistula 1 | 36
Transposition of Great Vessels 1 | 2
Urethral atresia 1 | 4
Velocardiofacial syndrome 1 | 46
Visceral heterotaxy 5, autosomal 1 | 1
X- linked recessive 1 | 110
agnathia-otocephaly complex 1 | 8
protein-losing enteropathy 1 | 12

Tissue

Endocrine System 9 | 18,159
Skin and soft tissues 9 | 17,230
Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Urinary Tract 8 | 16,678
Respiratory system 7 | 16,393

Target Family

Non-IDG 4 | 12,091
Enzyme 2 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Transcription Factor 1 | 1,400

UniProt Keyword

Heterotaxy 9 | 9
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polypeptide N-acetylgalactosaminyltransferase 11 GALNT11 Tbio Enzyme -0.66996 5.39 88
Cryptic protein CFC1 Tbio Non-IDG -1.89131 76.4 159
Zinc finger protein ZIC 3 ZIC3 Tbio Transcription Factor -3.08151 1223.6 173
Polycystic kidney disease protein 1-like 1 PKD1L1 Tdark Ion Channel -0.57320 5.37 29
Matrix metalloproteinase-21 MMP21 Tbio Enzyme -0.93950 8.94 55
Cilia- and flagella-associated protein 53 CFAP53 Tbio Non-IDG -0.71739 5.69 55
Activin receptor type-2B ACVR2B Tchem Kinase -2.14321 122.9 303
Nodal homolog NODAL Tbio Non-IDG -3.00545 981.7 245
Left-right determination factor 2 LEFTY2 Tbio Non-IDG -2.02866 98.4 187