Development Level

Tbio 68 | 11,445
Tchem 15 | 1,598
Tclin 6 | 613

IMPC Phenotype

abnormal bone structure 3 | 187
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
abnormal retinal vasculature m... 2 | 27
abnormal seminal vesicle morph... 2 | 114
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
impaired righting response 2 | 26
increased mean corpuscular hem... 2 | 36
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cleft palate 1 | 8
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
premature death 1 | 5
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 56 | 11,493
ovarian cancer 46 | 8,520
psoriasis 42 | 6,694
glioblastoma 39 | 5,792
Cancer 36 | 2,499
osteosarcoma 36 | 7,950
Breast cancer 34 | 3,578
lung cancer 34 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
medulloblastoma, large-cell 33 | 6,241
invasive ductal carcinoma 32 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
lung carcinoma 31 | 2,843
malignant mesothelioma 31 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
lung adenocarcinoma 30 | 2,716
non-small cell lung cancer 30 | 2,890
atypical teratoid / rhabdoid tumor 29 | 5,112
ependymoma 29 | 4,679
interstitial cystitis 29 | 2,312
cystic fibrosis 28 | 1,696
pancreatic cancer 27 | 2,398
Astrocytoma, Pilocytic 25 | 3,081
adult high grade glioma 25 | 3,801
group 3 medulloblastoma 25 | 4,104
ulcerative colitis 22 | 1,819
breast carcinoma 20 | 1,638
diabetes mellitus 20 | 1,728
oligodendroglioma 19 | 2,850
Kidney cancer 18 | 2,613
ductal carcinoma in situ 18 | 1,745
Autosomal recessive predisposition 17 | 1,442
colon cancer 17 | 1,478
nasopharyngeal carcinoma 17 | 1,058
primitive neuroectodermal tumor 17 | 3,035
Atherosclerosis 16 | 291
gastric carcinoma 16 | 807
pituitary cancer 16 | 1,972
primary pancreatic ductal adenocarcinoma 16 | 1,109
adrenocortical carcinoma 15 | 1,428
astrocytic glioma 15 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Atopic dermatitis 14 | 952
Hypertension 14 | 396
Schizophrenia 13 | 1,160
Hypertensive disease 12 | 292
Kidney disease 12 | 430
tuberculosis 12 | 2,010
Coronary artery disease 11 | 268
Heart disease 11 | 306
Liver Cirrhosis 10 | 181
Liver Cirrhosis, Experimental 10 | 769
Vascular disease 10 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
fibroadenoma 10 | 559
juvenile dermatomyositis 10 | 1,187
subependymal giant cell astrocytoma 10 | 2,287
Breast Neoplasms 9 | 445
Duchenne muscular dystrophy 9 | 601
Mammary Neoplasms 9 | 425
Rheumatoid arthritis 9 | 1,191
cutaneous lupus erythematosus 9 | 1,057
mucosa-associated lymphoid tissue lymphoma 9 | 484
Alzheimer's disease 8 | 658
Cerebrovascular disease 8 | 238
Down syndrome 8 | 499
Obesity 8 | 678
Seizures 8 | 596
active ulcerative colitis 8 | 764
astrocytoma 8 | 1,146
esophageal adenocarcinoma 8 | 737
limb girdle muscular dystrophy 2A 8 | 213
Arthritis 7 | 290
Cardiovascular system disease 7 | 246
Endometriosis 7 | 540
Glaucoma 7 | 239
Melanoma 7 | 711
Thrombophilia 7 | 38
acute quadriplegic myopathy 7 | 1,158
medulloblastoma 7 | 720
non primary Sjogren syndrome sicca 7 | 891
Abortion, Spontaneous 6 | 109
Cleft Palate 6 | 271
Depressive disorder 6 | 409
Dull intelligence 6 | 645
Intellectual disability 6 | 1,016
Lipid metabolism disorder 6 | 114
Low intelligence 6 | 645
Lung Neoplasms 6 | 232
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Mesothelioma, Malignant 6 | 105
Osteoporosis 6 | 363
Poor school performance 6 | 645
Short stature 6 | 531
Spontaneous abortion 6 | 113
atypical teratoid/rhabdoid tumor 6 | 357
hepatocellular carcinoma 6 | 547
interstitial lung disease 6 | 298
nephrosclerosis 6 | 333

Tissue

Endocrine System 88 | 18,159
Liver and Pancreas 88 | 16,750
Digestive Tract 87 | 17,369
Female tissues 87 | 17,400
Skin and soft tissues 87 | 17,230
Blood and immune system 86 | 16,909
Urinary Tract 85 | 16,678
Respiratory system 84 | 16,393
Male tissues 83 | 17,142
Nervous System 80 | 16,725
Cardiovascular System 72 | 15,192

Target Family

Non-IDG 64 | 12,091
Enzyme 20 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 408
Transcription Factor 1 | 1,400

UniProt Keyword

Heparin-binding 89 | 89
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Latexin LXN Tbio Enzyme -2.54426 344.4 419
A disintegrin and metalloproteinase with thrombospondin motifs 8 ADAMTS8 Tbio Enzyme -1.14483 14.5 153
Collagen alpha-1(XXV) chain COL25A1 Tbio Non-IDG -0.99093 10.6 119
A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS1 Tchem Enzyme -2.44459 279.8 227
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
R-spondin-4 RSPO4 Tbio Non-IDG -1.45244 28.7 66
Megakaryocyte and platelet inhibitory receptor G6b MPIG6B Tbio Non-IDG -1.00429 11.8 53
Latent-transforming growth factor beta-binding protein 2 LTBP2 Tbio Non-IDG -1.22721 18.2 100
Follistatin-related protein 1 FSTL1 Tbio Non-IDG -1.98038 117.5 265
Adenosine deaminase 2 ADA2 Tbio Enzyme -1.43407 32.5 98