Development Level

Tbio 34 | 10,625
Tdark 2 | 7,003
Tchem 1 | 1,890
Tclin 1 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

increased or absent threshold ... 6 | 128
decreased prepulse inhibition 4 | 52
absent pinna reflex 3 | 21
absent startle reflex 3 | 15
decreased startle reflex 3 | 48
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating amylase ... 2 | 24
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
impaired righting response 2 | 19
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
stereotypic behavior 2 | 3
trunk curl 2 | 15
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal ear morphology 1 | 5
abnormal glucose homeostasis 1 | 5
abnormal locomotor activation 1 | 26
abnormal respiratory quotient 1 | 9
abnormal vibrissa morphology 1 | 17
decreased body weight 1 | 174
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
limb grasping 1 | 35
persistence of hyaloid vascula... 1 | 22

Disease

Nonsyndromic deafness 35 | 121
Sensorineural hearing loss 24 | 107
psoriasis 16 | 6,685
Hodgkin's lymphoma, nodular sclerosis 12 | 24
medulloblastoma, large-cell 12 | 6,234
osteosarcoma 12 | 7,933
ovarian cancer 11 | 8,484
Carcinoma 10 | 2,147
Usher syndrome 10 | 34
lung carcinoma 9 | 2,844
Blindness 8 | 84
Retinitis pigmentosa 8 | 153
cystic fibrosis 8 | 1,665
interstitial cystitis 8 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
spina bifida 8 | 1,064
ependymoma 7 | 2,514
glioblastoma 7 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
invasive ductal carcinoma 7 | 2,950
Deafness 6 | 18
adult high grade glioma 6 | 2,148
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
lung adenocarcinoma 6 | 2,713
non-small cell lung cancer 6 | 2,798
oligodendroglioma 6 | 2,849
pilocytic astrocytoma 6 | 3,086
pituitary cancer 6 | 1,972
Breast cancer 5 | 3,094
astrocytic glioma 5 | 2,241
atypical teratoid / rhabdoid tumor 5 | 4,369
ductal carcinoma in situ 5 | 1,745
lung cancer 5 | 4,466
malignant mesothelioma 5 | 3,162
pediatric high grade glioma 5 | 2,712
Atopic dermatitis 4 | 944
fibroadenoma 4 | 557
group 3 medulloblastoma 4 | 2,254
pancreatic cancer 4 | 2,300
posterior fossa group A ependymoma 4 | 1,511
primitive neuroectodermal tumor 4 | 3,031
sonic hedgehog group medulloblastoma 4 | 1,482
Epilepsy 3 | 346
Neuropathy 3 | 210
Pick disease 3 | 1,893
Usher Syndrome, Type II 3 | 4
Usher syndrome type 2 3 | 4
atypical teratoid/rhabdoid tumor 3 | 1,095
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,875
medulloblastoma 3 | 1,524
posterior fossa group B ependymoma 3 | 1,530
primary pancreatic ductal adenocarcinoma 3 | 1,271
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 2,087
Bart-Pumphrey syndrome 2 | 4
Clouston syndrome 2 | 9
DEAFNESS, AUTOSOMAL DOMINANT 3A (disorder) 2 | 2
DEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder) 2 | 3
DEAFNESS, DIGENIC, GJB2/GJB6 (disorder) 2 | 2
Enlarged vestibular aqueduct 2 | 10
Erythrokeratodermia variabilis 2 | 10
Hypertensive disease 2 | 193
Keratitis 2 | 42
Keratosis 2 | 34
Kidney cancer 2 | 118
Leber congenital amaurosis 2 | 72
Multiple Sclerosis 2 | 498
Palmoplantar keratosis 2 | 36
Rheumatoid Arthritis 2 | 1,160
Substance-Related Disorders 2 | 114
USHER SYNDROME, TYPE ID 2 | 2
USHER SYNDROME, TYPE IG 2 | 2
Usher syndrome, type 1D 2 | 2
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
astrocytoma 2 | 1,493
breast carcinoma 2 | 1,614
dermatomyositis 2 | 933
facioscapulohumeral dystrophy 2 | 286
gastric cancer 2 | 430
gastric carcinoma 2 | 832
hepatocellular carcinoma 2 | 532
nasopharyngeal carcinoma 2 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
tuberculosis 2 | 1,557
tuberculosis and treatment for 3 months 2 | 327
Central retinal artery occlusion 1 | 3
Glomangiomatosis 1 | 4
Hepatitis 1 | 61
Hypotension 1 | 53
Kidney failure 1 | 39
Noise-induced hearing loss 1 | 5
Oculodentodigital dysplasia 1 | 14
Phaeochromocytoma 1 | 20
Skin Neoplasms 1 | 49
Small head 1 | 9
Uveitis 1 | 103
Wolfram syndrome 1 | 11

Tissue

Digestive Tract 38 | 18,473
Endocrine System 38 | 18,512
Female tissues 38 | 18,647
Nervous System 38 | 18,561
Urinary Tract 38 | 18,444
Blood and immune system 37 | 17,995
Liver and Pancreas 37 | 18,136
Skin and soft tissues 37 | 18,115
Cardiovascular System 36 | 17,958
Male tissues 36 | 17,969
Respiratory system 36 | 17,484

Target Family

Non-IDG 28 | 11,971
Ion Channel 4 | 341
Transporter 3 | 473
Enzyme 2 | 4,146
Kinase 1 | 634

UniProt Keyword

Hearing 38 | 38
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stereocilin STRC Tbio Non-IDG 35.9 7
Otoancorin OTOA Tdark Non-IDG -1.29628 19.3 48
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.97274 103.1 38
Transmembrane O-methyltransferase LRTOMT Tbio Enzyme 13.4 29
Lipoxygenase homology domain-containing protein 1 LOXHD1 Tbio Enzyme -0.76399 6.47 8
Taperin TPRN Tbio Non-IDG -0.72520 6.12 29
Cochlin COCH Tbio Non-IDG -2.47329 307.4 144
Harmonin USH1C Tbio Non-IDG -2.04033 115.8 173
Glutaredoxin domain-containing cysteine-rich protein 1 GRXCR1 Tdark Non-IDG -0.62411 4.29 35
Phospholipid-transporting ATPase IC ATP8B1 Tbio Transporter -2.41239 255.3 15