Development Level

Tbio 53 | 11,651
Tchem 5 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal eye morphology 2 | 68
decreased body weight 2 | 161
decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased circulating creatine... 1 | 5
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

ovarian cancer 41 | 8,520
Carcinoma 33 | 11,493
medulloblastoma, large-cell 26 | 6,241
osteosarcoma 26 | 7,950
atypical teratoid / rhabdoid tumor 25 | 5,112
Cancer 24 | 2,499
glioblastoma 24 | 5,792
Breast cancer 23 | 3,578
psoriasis 23 | 6,694
ependymoma 21 | 4,679
lung cancer 20 | 4,740
malignant mesothelioma 20 | 3,232
group 3 medulloblastoma 19 | 4,104
adult high grade glioma 17 | 3,801
Astrocytoma, Pilocytic 16 | 3,081
non-small cell lung cancer 16 | 2,890
primitive neuroectodermal tumor 16 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
lung adenocarcinoma 12 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
tuberculosis 11 | 2,010
Multiple myeloma 10 | 1,332
breast carcinoma 10 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
invasive ductal carcinoma 10 | 2,951
pituitary cancer 10 | 1,972
adrenocortical carcinoma 9 | 1,428
cystic fibrosis 9 | 1,696
diabetes mellitus 9 | 1,728
lung carcinoma 9 | 2,843
oligodendroglioma 9 | 2,850
hepatocellular carcinoma 8 | 547
juvenile dermatomyositis 8 | 1,187
pancreatic cancer 8 | 2,398
Liver Cirrhosis, Experimental 7 | 769
Pick disease 7 | 1,894
acute quadriplegic myopathy 7 | 1,158
colon cancer 7 | 1,478
subependymal giant cell astrocytoma 7 | 2,287
Kidney cancer 6 | 2,613
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
astrocytoma 6 | 1,146
interstitial cystitis 6 | 2,312
non primary Sjogren syndrome sicca 6 | 891
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
ulcerative colitis 6 | 1,819
Alzheimer's disease 5 | 658
Bipolar Disorder 5 | 666
Waldenstrons macroglobulinemia 5 | 765
active ulcerative colitis 5 | 764
astrocytic glioma 5 | 2,597
medulloblastoma 5 | 720
spina bifida 5 | 1,074
Cardiomegaly 4 | 116
Dermatitis, Allergic Contact 4 | 67
ductal carcinoma in situ 4 | 1,745
primary pancreatic ductal adenocarcinoma 4 | 1,109
Acquired scoliosis 3 | 281
Adenoid Cystic Carcinoma 3 | 99
Aortic aneurysm 3 | 38
Arthritis 3 | 290
Atopic dermatitis 3 | 952
Carcinoma, Adenoid Cystic 3 | 99
Colonic Neoplasms 3 | 142
Coronary artery disease 3 | 268
Curvature of spine 3 | 282
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Hepatitis C 3 | 94
Liver disease 3 | 237
Lung Neoplasms 3 | 232
Multiple Sclerosis 3 | 540
Obesity 3 | 678
Orbital separation excessive 3 | 244
Prader-Willi syndrome 3 | 48
Prostatic Neoplasms 3 | 495
Vascular disease 3 | 319
chronic lymphosyte leukemia 3 | 204
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
facioscapulohumeral dystrophy 3 | 288
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
pancreatic carcinoma 3 | 562
periodontitis 3 | 293
sonic hedgehog group medulloblastoma 3 | 467
Adenoma 2 | 167
Atherosclerosis 2 | 291
Byzanthine arch palate 2 | 194
Craniosynostosis 2 | 74
Delayed speech and language development 2 | 112
Inflammatory bowel disease 2 | 151
Language Delay 2 | 112
Malaria 2 | 160
Speech Delay 2 | 112
Speech impairment 2 | 112
Type 2 diabetes mellitus 2 | 272
active Crohn's disease 2 | 922

Tissue

Blood and immune system 59 | 16,909
Digestive Tract 59 | 17,369
Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Liver and Pancreas 59 | 16,750
Male tissues 59 | 17,142
Nervous System 59 | 16,725
Respiratory system 59 | 16,393
Skin and soft tissues 59 | 17,230
Urinary Tract 59 | 16,678
Cardiovascular System 58 | 15,192

Target Family

Non-IDG 48 | 12,091
Epigenetic 5 | 242
Kinase 3 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

UniProt Keyword

Growth regulation 59 | 59
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Malignant T-cell-amplified sequence 1 MCTS1 Tbio Non-IDG -0.79616 5.89 149
Oxidative stress-induced growth inhibitor 1 OSGIN1 Tbio Non-IDG -1.21621 17.2 104
MRG/MORF4L-binding protein MRGBP Tbio Non-IDG -0.74186 5.72 147
Opioid growth factor receptor OGFR Tbio Non-IDG -1.86929 79.4 89
Receptor of activated protein C kinase 1 RACK1 Tbio Non-IDG -2.60480 437.9 300
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
Transcription factor E4F1 E4F1 Tbio Transcription Factor -1.47265 33.6 87
Interferon gamma IFNG Tbio Non-IDG -3.90985 5727.4 2248
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.05851 1163.8 469
Oncostatin-M OSM Tbio Non-IDG -2.54044 421.5 433