Development Level

Tbio 111 | 11,651
Tchem 12 | 1,388
Tclin 7 | 612
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 10 | 979
decreased vertical activity 4 | 208
embryonic lethality prior to t... 4 | 278
increased mean corpuscular vol... 3 | 92
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
decreased circulating fructosa... 2 | 30
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
hydrometra 2 | 53
hypoactivity 2 | 132
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
limb grasping 2 | 41
short tibia 2 | 97
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal optic disc morphology 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cleft palate 1 | 8
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged uterus 1 | 11
female infertility 1 | 60
fused cornea and lens 1 | 5
hemorrhage 1 | 23
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
male infertility 1 | 123
narrow eye opening 1 | 12
no spontaneous movement 1 | 1
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Cancer 69 | 2,499
lung cancer 57 | 4,740
psoriasis 57 | 6,694
Carcinoma 55 | 11,493
malignant mesothelioma 49 | 3,232
ovarian cancer 49 | 8,520
osteosarcoma 44 | 7,950
glioblastoma 41 | 5,792
Breast cancer 40 | 3,578
ependymoma 35 | 4,679
interstitial cystitis 34 | 2,312
lung adenocarcinoma 33 | 2,716
medulloblastoma, large-cell 33 | 6,241
lung carcinoma 31 | 2,843
invasive ductal carcinoma 30 | 2,951
diabetes mellitus 29 | 1,728
atypical teratoid / rhabdoid tumor 28 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
cystic fibrosis 25 | 1,696
Astrocytoma, Pilocytic 24 | 3,081
adult high grade glioma 24 | 3,801
group 3 medulloblastoma 24 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
pancreatic cancer 24 | 2,398
Schizophrenia 23 | 1,160
non-small cell lung cancer 23 | 2,890
colon cancer 22 | 1,478
oligodendroglioma 22 | 2,850
Breast Neoplasms 21 | 445
Mammary Neoplasms 21 | 425
ulcerative colitis 21 | 1,819
Pulmonary Fibrosis 20 | 106
ductal carcinoma in situ 20 | 1,745
pituitary cancer 20 | 1,972
Autosomal recessive predisposition 19 | 1,442
breast carcinoma 19 | 1,638
tuberculosis 19 | 2,010
Liver Cirrhosis, Experimental 18 | 769
Depressive disorder 17 | 409
Asthma 16 | 385
Atopic dermatitis 16 | 952
Bipolar Disorder 16 | 666
Cleft Palate 16 | 271
group 4 medulloblastoma 16 | 1,855
Arthritis 14 | 290
Kidney disease 14 | 430
Liver carcinoma 14 | 240
Mental Depression 14 | 333
Neuropathy 14 | 261
Rheumatoid arthritis 14 | 1,191
Anemia 13 | 365
Atherosclerosis 13 | 291
Carcinoma, Hepatocellular 13 | 228
Endometriosis 13 | 540
Mesothelioma, Malignant 13 | 105
Obesity 13 | 678
Osteoporosis 13 | 363
Polycystic ovary syndrome 13 | 360
astrocytic glioma 13 | 2,597
gastric carcinoma 13 | 807
Coronary artery disease 12 | 268
Heart disease 12 | 306
Lung disease 12 | 142
Multiple Sclerosis 12 | 540
Neoplasm Metastasis 12 | 168
Parkinson's disease 12 | 392
Prostatic Neoplasms 12 | 495
Vascular disease 12 | 319
juvenile dermatomyositis 12 | 1,187
primitive neuroectodermal tumor 12 | 3,035
Abortion, Spontaneous 11 | 109
Alzheimer's disease 11 | 658
Cleft Lip 11 | 141
Hypersensitivity reaction type II disease 11 | 253
Inflammatory bowel disease 11 | 151
Major Depressive Disorder 11 | 301
Spontaneous abortion 11 | 113
adrenocortical carcinoma 11 | 1,428
cutaneous lupus erythematosus 11 | 1,057
fibroadenoma 11 | 559
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
subependymal giant cell astrocytoma 11 | 2,287
Autistic Disorder 10 | 364
Cerebrovascular disease 10 | 238
Down syndrome 10 | 499
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
nasopharyngeal carcinoma 10 | 1,058
Dermatitis 9 | 157
Inflammation 9 | 120
Myocardial Ischemia 9 | 169
Neoplasm Invasiveness 9 | 161
Nerve Degeneration 9 | 121
Osteoarthritis 9 | 184
Reperfusion Injury 9 | 86
Short stature 9 | 531
Stomach Neoplasms 9 | 300
Thrombocytopenia 9 | 197
non-small cell lung carcinoma 9 | 317
primary pancreatic ductal adenocarcinoma 9 | 1,109

Tissue

Endocrine System 127 | 18,159
Female tissues 122 | 17,400
Digestive Tract 121 | 17,369
Skin and soft tissues 121 | 17,230
Liver and Pancreas 120 | 16,750
Male tissues 119 | 17,142
Nervous System 118 | 16,725
Urinary Tract 118 | 16,678
Blood and immune system 116 | 16,909
Respiratory system 113 | 16,393
Cardiovascular System 105 | 15,192

Target Family

Non-IDG 125 | 12,091
Enzyme 5 | 4,145
Epigenetic 2 | 242

UniProt Keyword

Growth factor 132 | 132
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Thymidine phosphorylase TYMP Tclin Enzyme -2.83170 677.8 514
Platelet-derived growth factor C PDGFC Tbio Non-IDG -2.03910 120.6 226
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Bone morphogenetic protein 15 BMP15 Tbio Non-IDG -2.33917 221.7 200
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Ciliary neurotrophic factor CNTF Tbio Non-IDG -2.96004 1015.5 485
Protransforming growth factor alpha TGFA Tbio Non-IDG -2.15761 135.3 697
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Nodal homolog NODAL Tbio Non-IDG -3.00545 981.7 245