Development Level

Tbio 603 | 10,625
Tdark 125 | 7,003
Tchem 81 | 1,890
Tclin 10 | 602

Collection

Eligible Kinase Proteins 7 | 134
Eligible Ion Channel Proteins 3 | 117

IMPC Term

preweaning lethality, complete... 36 | 633
decreased total body fat amoun... 15 | 186
decreased lean body mass 14 | 195
embryonic lethality prior to t... 13 | 187
decreased bone mineral content 12 | 157
decreased body weight 11 | 174
increased lean body mass 11 | 107
increased mean corpuscular hem... 11 | 93
preweaning lethality, incomple... 10 | 260
decreased bone mineral density 9 | 126
increased bone mineral content 9 | 92
abnormal behavior 8 | 226
abnormal bone structure 8 | 131
decreased circulating serum al... 8 | 79
decreased grip strength 8 | 123
increased mean corpuscular vol... 8 | 91
abnormal retina morphology 7 | 100
decreased body length 7 | 108
decreased circulating HDL chol... 7 | 77
decreased circulating LDL chol... 7 | 37
decreased circulating choleste... 7 | 85
decreased circulating triglyce... 7 | 83
abnormal embryo size 6 | 112
abnormal sleep behavior 6 | 63
decreased circulating alanine ... 6 | 53
increased circulating alkaline... 6 | 119
abnormal lens morphology 5 | 73
decreased circulating insulin ... 5 | 75
decreased rib number 5 | 59
embryonic lethality prior to o... 5 | 148
hypoactivity 5 | 89
increased or absent threshold ... 5 | 128
male infertility 5 | 62
straub tail 5 | 26
abnormal eye morphology 4 | 38
abnormal limb bud morphology 4 | 15
abnormal neural tube closure 4 | 37
decreased circulating fructosa... 4 | 31
decreased circulating glucose ... 4 | 121
decreased fasted circulating g... 4 | 49
decreased heart weight 4 | 44
decreased lumbar vertebrae num... 4 | 62
enlarged heart 4 | 111
hyperactivity 4 | 108
increased blood urea nitrogen ... 4 | 44
increased circulating sodium l... 4 | 71
increased sacral vertebrae num... 4 | 62
abnormal behavioral response t... 3 | 52
abnormal cranium morphology 3 | 32
abnormal gait 3 | 51
abnormal head morphology 3 | 10
abnormal kidney morphology 3 | 30
abnormal limb morphology 3 | 7
abnormal retinal pigmentation 3 | 61
abnormal testis morphology 3 | 30
cardiovascular system phenotyp... 3 | 35
decreased CD8-positive, alpha-... 3 | 26
decreased NK T cell number 3 | 28
decreased T cell number 3 | 31
decreased caudal vertebrae num... 3 | 49
decreased circulating calcium ... 3 | 33
decreased circulating creatini... 3 | 31
decreased leukocyte cell numbe... 3 | 54
decreased mean corpuscular hem... 3 | 34
decreased prepulse inhibition 3 | 52
hydrops fetalis 3 | 22
increased body weight 3 | 42
increased bone mineral density 3 | 52
increased circulating chloride... 3 | 43
increased circulating serum al... 3 | 25
increased fasted circulating g... 3 | 68
increased grip strength 3 | 83
increased heart weight 3 | 37
increased mean corpuscular hem... 3 | 25
increased mean platelet volume 3 | 19
increased red blood cell distr... 3 | 21
persistence of hyaloid vascula... 3 | 22
short tibia 3 | 82
shortened RR interval 3 | 19
thrombocytosis 3 | 23
abnormal coat appearance 2 | 25
abnormal epididymis morphology 2 | 31
abnormal heart morphology 2 | 51
abnormal lung morphology 2 | 15
abnormal spleen morphology 2 | 36
abnormal vibrissa morphology 2 | 17
decreased NK cell number 2 | 16
decreased circulating potassiu... 2 | 17
decreased hemoglobin content 2 | 53
decreased vertical activity 2 | 22
enlarged spleen 2 | 26
impaired glucose tolerance 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating calcium ... 2 | 32
increased circulating fructosa... 2 | 11
increased erythrocyte cell num... 2 | 26
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
small testis 2 | 37
tremors 2 | 34

Disease

ovarian cancer 480 | 8,484
osteosarcoma 405 | 7,933
medulloblastoma, large-cell 324 | 6,234
glioblastoma 321 | 5,572
psoriasis 303 | 6,685
atypical teratoid / rhabdoid tumor 245 | 4,369
lung cancer 211 | 4,466
pilocytic astrocytoma 192 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 188 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 187 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 181 | 3,289
Breast cancer 176 | 3,094
invasive ductal carcinoma 158 | 2,950
lung carcinoma 156 | 2,844
lung adenocarcinoma 154 | 2,713
malignant mesothelioma 152 | 3,162
oligodendroglioma 144 | 2,849
pancreatic cancer 136 | 2,300
non-small cell lung cancer 134 | 2,798
pediatric high grade glioma 132 | 2,712
ependymoma 130 | 2,514
adult high grade glioma 128 | 2,148
primitive neuroectodermal tumor 124 | 3,031
group 4 medulloblastoma 123 | 1,875
interstitial cystitis 115 | 2,299
subependymal giant cell astrocytoma 112 | 2,287
astrocytic glioma 109 | 2,241
Pick disease 108 | 1,893
pituitary cancer 107 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 105 | 1,795
ulcerative colitis 98 | 2,087
astrocytoma 97 | 1,493
ductal carcinoma in situ 88 | 1,745
tuberculosis 87 | 1,557
cystic fibrosis 86 | 1,665
Carcinoma 85 | 2,147
Multiple myeloma 85 | 1,327
group 3 medulloblastoma 82 | 2,254
breast carcinoma 81 | 1,614
posterior fossa group B ependymoma 80 | 1,530
medulloblastoma 79 | 1,524
diabetes mellitus 78 | 1,663
posterior fossa group A ependymoma 78 | 1,511
juvenile dermatomyositis 76 | 1,189
primary pancreatic ductal adenocarcinoma 76 | 1,271
adrenocortical carcinoma 68 | 1,427
colon cancer 68 | 1,475
Cancer 67 | 2,346
active Crohn's disease 65 | 918
spina bifida 64 | 1,064
Rheumatoid Arthritis 63 | 1,160
acute quadriplegic myopathy 59 | 1,157
dermatomyositis 58 | 933
atypical teratoid/rhabdoid tumor 55 | 1,095
non primary Sjogren syndrome sicca 54 | 840
tuberculosis and treatment for 6 months 54 | 686
sonic hedgehog group medulloblastoma 53 | 1,482
primary Sjogren syndrome 52 | 789
Alzheimer's disease 51 | 644
cutaneous lupus erythematosus 49 | 1,056
pancreatic carcinoma 47 | 567
progressive supranuclear palsy 44 | 674
nasopharyngeal carcinoma 41 | 1,056
gastric carcinoma 40 | 832
Intellectual disability 39 | 573
aldosterone-producing adenoma 38 | 664
active ulcerative colitis 37 | 477
esophageal adenocarcinoma 37 | 737
hepatocellular carcinoma 36 | 532
hereditary spastic paraplegia 35 | 313
Waldenstrons macroglobulinemia 34 | 765
Down syndrome 33 | 548
Atopic dermatitis 32 | 944
Duchenne muscular dystrophy 32 | 602
IGA Glomerulonephritis 32 | 454
acute myeloid leukemia 30 | 780
gastric cancer 29 | 430
Multiple Sclerosis 28 | 498
Neurodegenerative disease 27 | 383
fibroadenoma 26 | 557
mucosa-associated lymphoid tissue lymphoma 26 | 480
Schizophrenia 25 | 501
sarcoidosis 25 | 358
Amyotrophic Lateral Sclerosis 24 | 431
Prostatic Neoplasms 23 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 22 | 499
non-small cell lung carcinoma 21 | 413
Obesity 20 | 616
Heart disease 18 | 279
Polycystic Ovary Syndrome 18 | 332
glioblastoma multiforme 18 | 347
inflammatory breast cancer 17 | 404
Chronic Lymphocytic Leukemia 16 | 242
Endometriosis 16 | 535
Mammary Neoplasms 16 | 410
Parkinson's disease 16 | 364
nephrosclerosis 16 | 329
Epilepsy 15 | 346
chronic rhinosinusitis 15 | 512
tuberculosis and treatment for 3 months 15 | 327

Tissue

Nervous System 800 | 18,561
Digestive Tract 799 | 18,473
Endocrine System 797 | 18,512
Female tissues 797 | 18,647
Liver and Pancreas 796 | 18,136
Cardiovascular System 794 | 17,958
Male tissues 794 | 17,969
Urinary Tract 794 | 18,444
Blood and immune system 793 | 17,995
Respiratory system 785 | 17,484
Skin and soft tissues 783 | 18,115

Target Family

Non-IDG 415 | 11,971
Enzyme 323 | 4,146
Transporter 33 | 473
Kinase 28 | 634
Ion Channel 8 | 341
GPCR 6 | 406
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

UniProt Keyword

Golgi apparatus 819 | 819
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..