Development Level

Tbio 162 | 11,651
Tdark 36 | 6,593
Tchem 21 | 1,388
Tclin 8 | 612

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 9 | 499
embryonic lethality prior to o... 7 | 239
enlarged heart 6 | 210
abnormal heart morphology 5 | 162
embryonic lethality prior to t... 5 | 278
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased hemoglobin content 3 | 68
decreased total body fat amoun... 3 | 207
hypoactivity 3 | 132
increased lean body mass 3 | 172
abnormal behavioral response t... 2 | 66
abnormal neural tube morpholog... 2 | 12
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
abnormal vibrissa morphology 2 | 25
cataract 2 | 92
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
enlarged spleen 2 | 41
increased bone mineral content 2 | 108
increased monocyte cell number 2 | 63
increased total body fat amoun... 2 | 134
long tibia 2 | 25
pale yolk sac 2 | 25
abnormal allantois morphology 1 | 8
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal esophagus morphology 1 | 5
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal somite shape 1 | 5
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
bleb 1 | 2
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased respiratory quotient 1 | 16
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged lung 1 | 2
hydroencephaly 1 | 14
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
scaly skin 1 | 4
short tibia 1 | 97
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 170 | 11,493
ovarian cancer 109 | 8,520
osteosarcoma 96 | 7,950
psoriasis 90 | 6,694
glioblastoma 72 | 5,792
medulloblastoma, large-cell 66 | 6,241
atypical teratoid / rhabdoid tumor 65 | 5,112
lung cancer 60 | 4,740
ependymoma 58 | 4,679
Astrocytoma, Pilocytic 46 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,291
Breast cancer 42 | 3,578
adult high grade glioma 42 | 3,801
lung adenocarcinoma 41 | 2,716
malignant mesothelioma 41 | 3,232
group 3 medulloblastoma 38 | 4,104
pancreatic cancer 38 | 2,398
primitive neuroectodermal tumor 37 | 3,035
non-small cell lung cancer 36 | 2,890
pituitary cancer 35 | 1,972
invasive ductal carcinoma 34 | 2,951
lung carcinoma 34 | 2,843
Kidney cancer 31 | 2,613
cystic fibrosis 30 | 1,696
group 4 medulloblastoma 30 | 1,855
interstitial cystitis 29 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,962
Autosomal recessive predisposition 28 | 1,442
tuberculosis 28 | 2,010
astrocytic glioma 26 | 2,597
oligodendroglioma 26 | 2,850
subependymal giant cell astrocytoma 26 | 2,287
Cancer 24 | 2,499
Pick disease 21 | 1,894
Epilepsy 20 | 792
active Crohn's disease 20 | 922
ulcerative colitis 19 | 1,819
Congenital disorder of glycosylation 18 | 54
Multiple myeloma 18 | 1,332
colon cancer 18 | 1,478
ductal carcinoma in situ 18 | 1,745
Intellectual disability 17 | 1,016
Muscle hypotonia 16 | 571
active ulcerative colitis 16 | 764
breast carcinoma 16 | 1,638
non primary Sjogren syndrome sicca 16 | 891
pediatric high grade glioma 16 | 1,064
primary pancreatic ductal adenocarcinoma 15 | 1,109
spina bifida 15 | 1,074
Anemia 14 | 365
Seizures 14 | 596
cutaneous lupus erythematosus 14 | 1,057
diabetes mellitus 14 | 1,728
nasopharyngeal carcinoma 14 | 1,058
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
gastric carcinoma 13 | 807
acute myeloid leukemia 12 | 783
adrenocortical carcinoma 12 | 1,428
Atopic dermatitis 11 | 952
juvenile dermatomyositis 11 | 1,187
Dull intelligence 10 | 645
Failure to gain weight 10 | 365
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Muscular dystrophy 10 | 75
Myopathy 10 | 185
Pediatric failure to thrive 10 | 365
Poor school performance 10 | 645
Prostatic Neoplasms 10 | 495
Schizophrenia 10 | 1,160
Walker-Warburg syndrome 10 | 20
acute quadriplegic myopathy 10 | 1,158
astrocytoma 10 | 1,146
esophageal adenocarcinoma 10 | 737
Arts syndrome 9 | 26
Congenital muscular dystrophy 9 | 29
Creatine phosphokinase serum increased 9 | 110
Elevated creatine kinase 9 | 110
Melanoma 9 | 711
Rheumatoid arthritis 9 | 1,191
Short stature 9 | 531
Sickle Cell Anemia 9 | 53
Small head 9 | 374
medulloblastoma 9 | 720
mucosa-associated lymphoid tissue lymphoma 9 | 484
primary Sjogren syndrome 9 | 735
Alzheimer's disease 8 | 658
Lissencephaly 8 | 69
Strabismus 8 | 270
facioscapulohumeral dystrophy 8 | 288
hepatocellular carcinoma 8 | 547
pancreatic carcinoma 8 | 562
progressive supranuclear palsy 8 | 676
Optic Atrophy 7 | 242
aldosterone-producing adenoma 7 | 665

Tissue

Digestive Tract 218 | 17,369
Liver and Pancreas 216 | 16,750
Endocrine System 215 | 18,159
Skin and soft tissues 214 | 17,230
Female tissues 213 | 17,400
Urinary Tract 213 | 16,678
Male tissues 210 | 17,142
Blood and immune system 207 | 16,909
Nervous System 202 | 16,725
Respiratory system 197 | 16,393
Cardiovascular System 183 | 15,192

Target Family

Enzyme 225 | 4,145
Non-IDG 2 | 12,091

UniProt Keyword

Glycosyltransferase 227 | 227
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
Beta-1,3-galactosyltransferase 1 B3GALT1 Tbio Enzyme -0.68296 3.85 66
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Thymidine phosphorylase TYMP Tclin Enzyme -2.83170 677.8 514
Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 Tbio Enzyme -2.80894 644.1 124
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H PIGH Tbio Enzyme -1.19063 13.0 116
Beta-1,3-galactosyltransferase 6 B3GALT6 Tbio Enzyme -1.00350 10.1 132
Poly [ADP-ribose] polymerase 3 PARP3 Tclin Enzyme -1.66230 41.9 193
Protein O-mannosyl-transferase 2 POMT2 Tbio Enzyme -1.48456 31.6 104
Alpha-(1,3)-fucosyltransferase 7 FUT7 Tchem Enzyme -1.85814 81.0 121