Development Level

Tbio 12 | 11,651
Tchem 8 | 1,388
Tdark 4 | 6,593
Tclin 2 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal glucose homeostasis 1 | 4
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
thrombocytosis 1 | 27

Disease

Carcinoma 18 | 11,493
osteosarcoma 12 | 7,950
ovarian cancer 10 | 8,520
medulloblastoma, large-cell 9 | 6,241
Glycogen storage disease 8 | 39
adult high grade glioma 8 | 3,801
glioblastoma 8 | 5,792
psoriasis 8 | 6,694
Kidney cancer 7 | 2,613
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
Cancer 6 | 2,499
tuberculosis 6 | 2,010
Autosomal recessive predisposition 5 | 1,442
Hepatomegaly 5 | 285
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Breast cancer 4 | 3,578
Duchenne muscular dystrophy 4 | 601
Hypertriglyceridemia result 4 | 37
Lafora disease 4 | 9
Pick disease 4 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
Depressive disorder 3 | 409
Epilepsy 3 | 792
Multiple myeloma 3 | 1,332
Muscle Weakness 3 | 170
Pain 3 | 103
Parkinson's disease 3 | 392
Renal Cell Carcinoma 3 | 214
Schizophrenia 3 | 1,160
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
pituitary cancer 3 | 1,972
Adult onset 2 | 82
Barre-Lieou syndrome 2 | 2
Bipolar disorder in remission 2 | 19
Carcinoma, Hepatocellular 2 | 228
Congenital stationary night blindness 2 | 29
Creatine phosphokinase serum increased 2 | 110
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Elevated creatine kinase 2 | 110
Elevated hepatic transaminases 2 | 81
Endometrial cancer 2 | 311
Exercise-induced myalgia 2 | 8
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hepatic enzyme increased 2 | 81
Hypoglycemia 2 | 152
Infantile onset 2 | 238
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Liver Dysfunction 2 | 99
Liver carcinoma 2 | 240
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Mental Depression 2 | 333
Mood Disorders 2 | 184
Motor delay 2 | 147
Myoglobinuria 2 | 15
Myopathy 2 | 185
No development of motor milestones 2 | 147
Osteoarthritis 2 | 184
Poor growth 2 | 114
Secondary hyperparathyroidism 2 | 6
Seizures 2 | 596
Skin cancer 2 | 469
Subclinical abnormal liver function tests 2 | 81
Toxic encephalopathy 2 | 141
Transaminases increased 2 | 81
Very poor growth 2 | 114
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
hereditary spastic paraplegia 2 | 318
medulloblastoma 2 | 720
post-traumatic stress disorder 2 | 40

Tissue

Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Male tissues 24 | 17,142
Skin and soft tissues 24 | 17,230
Blood and immune system 23 | 16,909
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Urinary Tract 23 | 16,678

Target Family

Enzyme 17 | 4,145
Kinase 8 | 634
Non-IDG 1 | 12,091

UniProt Keyword

Glycogen metabolism 26 | 26
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

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