Development Level

Tbio 5 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal behavior 1 | 298
abnormal tooth morphology 1 | 24
decreased body weight 1 | 161
decreased hemoglobin content 1 | 68
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic lethality prior to t... 1 | 278
increased heart weight 1 | 62
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 9 | 11,493
ovarian cancer 7 | 8,520
lung cancer 6 | 4,740
medulloblastoma, large-cell 5 | 6,241
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
ependymoma 3 | 4,679
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
nasopharyngeal carcinoma 3 | 1,058
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Exocrine pancreatic insufficiency 2 | 32
Feeding difficulties 2 | 127
Hyperglycemia 2 | 137
Multiple myeloma 2 | 1,332
Obesity 2 | 678
Pancreatic steatorrhea 2 | 6
Pick disease 2 | 1,894
Steatorrhea 2 | 34
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
glioblastoma 2 | 5,792
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Acute lymphoid leukemia 1 | 25
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Arthrogryposis 1 | 54
Axial hypotonia 1 | 46
Barrett's esophagus 1 | 182
Blepharoptosis 1 | 231
Chronic rhinitis 1 | 7
Class III malocclusion 1 | 78
Congenital myasthenic syndrome 1 | 25
Cortical gyral simplification 1 | 19
Defective T cell proliferation 1 | 1
Deglutition Disorders 1 | 132
Delayed myelination 1 | 22
Dilated ventricles (finding) 1 | 121
Dysarthria 1 | 192
Ehlers-Danlos syndrome 1 | 43
Encephalopathies 1 | 43
Gowers sign 1 | 24
Gowers sign present 1 | 24
Hypertrophy of lower jaw 1 | 78
Hypsarrhythmia 1 | 25
IMMUNODEFICIENCY 24 1 | 1
Immunoglobulin IgG2 deficiency 1 | 3
Immunologic Deficiency Syndromes 1 | 113
Increased size of mandible 1 | 78
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Leukemia, Myelocytic, Acute 1 | 120
Liver Neoplasms, Experimental 1 | 59
Lymphopenia 1 | 67
MYELODYSPLASTIC SYNDROME 1 | 53
Macrotia 1 | 87
Malocclusion 1 | 57
Mandibular hyperplasia 1 | 78
Mildly increased creatine kinase 1 | 20
Muscle atrophy, proximal 1 | 11
Myasthenias 1 | 8
Myasthenic Syndrome, Congenital, 4C, Associated With Acetylcholine Receptor Deficiency 1 | 5
Neck muscle weakness 1 | 17
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
No development of motor milestones 1 | 147
Ophthalmoparesis 1 | 11
Pontine hypoplasia 1 | 7
Progressive microcephaly 1 | 32
Reduced fetal movement 1 | 51
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Skeletal muscle atrophy 1 | 139
Spastic Quadriplegia 1 | 42
Waddling gait 1 | 34
X-linked cerebral adrenoleukodystrophy 1 | 116
mandibular excess (physical finding) 1 | 78
muscle degeneration 1 | 139

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 9 | 4,145

UniProt Keyword

Glutamine amidotransferase 9 | 9
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
Phosphoribosylformylglycinamidine synthase PFAS Tbio Enzyme -2.83741 653.1 88
Asparagine synthetase domain-containing protein 1 ASNSD1 Tdark Enzyme 1.41 0.02 103
GMP synthase [glutamine-hydrolyzing] GMPS Tbio Enzyme -2.48490 295.1 194
Asparagine synthetase [glutamine-hydrolyzing] ASNS Tchem Enzyme -2.40144 244.3 223
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 GFPT1 Tchem Enzyme -2.79406 584.2 135
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 GFPT2 Tbio Enzyme -2.69474 462.3 148
Amidophosphoribosyltransferase PPAT Tclin Enzyme -1.75730 56.1 198
CTP synthase 2 CTPS2 Tbio Enzyme -1.19705 14.4 157