Development Level

Tbio 10 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased body length 1 | 32
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
preweaning lethality, incomple... 1 | 499

Disease

Glaucoma 13 | 239
Carcinoma 11 | 11,493
osteosarcoma 9 | 7,950
ovarian cancer 9 | 8,520
medulloblastoma, large-cell 7 | 6,241
Blindness 6 | 88
lung adenocarcinoma 6 | 2,716
psoriasis 6 | 6,694
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
lung cancer 5 | 4,740
primary open angle glaucoma 5 | 16
GLAUCOMA 3, PRIMARY CONGENITAL, A 4 | 4
Glaucoma, Open-Angle 4 | 11
Glaucoma, Primary Open Angle 4 | 8
Hydrophthalmos 4 | 19
glioblastoma 4 | 5,792
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
primary congenital glaucoma 4 | 5
Axenfeld-Rieger syndrome 3 | 14
Cancer 3 | 2,499
Glaucoma 3, primary infantile, B 3 | 3
Myopia 3 | 176
Nerve Degeneration 3 | 121
Neurodegenerative disease 3 | 414
Pigment dispersion syndrome 3 | 11
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
ulcerative colitis 3 | 1,819
Acrofrontofacionasal dysostosis 2 | 4
Amyotrophic lateral sclerosis 2 | 451
Aniridia 2 | 25
Anxiety 2 | 136
Anxiety disease 2 | 113
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Cataract 2 | 297
Cerebral atrophy 2 | 178
Clouding of corneal stroma 2 | 50
Corneal Opacity 2 | 53
Deglutition Disorders 2 | 132
Depressive disorder 2 | 409
Dysarthria 2 | 192
Dyspnea 2 | 76
Exfoliation Syndrome 2 | 12
Fatigable weakness of respiratory muscles 2 | 28
Fatigable weakness of swallowing muscles 2 | 28
Fatigue 2 | 182
Frontotemporal dementia 2 | 51
GLAUCOMA 1, OPEN ANGLE, A 2 | 3
GLC3B 2 | 2
Generalized muscle weakness 2 | 57
Glaucoma of childhood 2 | 2
Glaucoma, congenital 2 | 2
Intellectual disability 2 | 1,016
Megalocornea 2 | 13
Melanoma 2 | 711
Mood swings 2 | 77
Muscle Cramp 2 | 55
Muscle Spasticity 2 | 195
Neuro-degenerative disease 2 | 43
Neurodegenerative Disorders 2 | 79
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Neuropathy 2 | 261
Ocular hypertension 2 | 42
Pain 2 | 103
Paralysed 2 | 42
Peters anomaly 2 | 16
Primary open angle glaucoma juvenile onset 1 2 | 2
Raised intraocular pressure 2 | 4
Respiratory Failure 2 | 104
Short stature 2 | 531
Skeletal muscle atrophy 2 | 139
Xerostomia 2 | 42
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
fascioscapulohumeral muscular dystrophy 2 | 100
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
muscle degeneration 2 | 139
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074

Tissue

Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Male tissues 13 | 17,142
Skin and soft tissues 13 | 17,230
Blood and immune system 12 | 16,909
Female tissues 12 | 17,400
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Urinary Tract 12 | 16,678
Liver and Pancreas 11 | 16,750

Target Family

Non-IDG 9 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634

UniProt Keyword

Glaucoma 13 | 13
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Latent-transforming growth factor beta-binding protein 2 LTBP2 Tbio Non-IDG -1.22721 18.2 100
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.55611 364.6 174
Calcium load-activated calcium channel TMCO1 Tbio Non-IDG -1.16473 12.8 26
G patch domain-containing protein 3 GPATCH3 Tbio Non-IDG 0.30 1.28 38
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 RPGRIP1 Tbio Enzyme -1.69109 46.2 64
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.93702 904.4 260
Angiopoietin-1 receptor TEK Tclin Kinase -3.00257 906.7 1009
Serine/threonine-protein kinase TBK1 TBK1 Tchem Kinase -2.76728 569.1 455
Ankyrin repeat and SOCS box protein 10 ASB10 Tbio Non-IDG -0.85286 7.76 117