Development Level

Tbio 23 | 11,445
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased vertical activity 3 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hydrometra 2 | 53
increased or absent threshold ... 2 | 101
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased caudal vertebrae num... 1 | 53
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
edema 1 | 59
enlarged spleen 1 | 41
enlarged uterus 1 | 11
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74

Disease

Carcinoma 19 | 11,493
osteosarcoma 14 | 7,950
psoriasis 14 | 6,694
ovarian cancer 12 | 8,520
adult high grade glioma 9 | 3,801
Erythrokeratodermia variabilis 8 | 10
interstitial cystitis 8 | 2,312
medulloblastoma, large-cell 8 | 6,241
Oculodentodigital dysplasia 7 | 14
group 3 medulloblastoma 7 | 4,104
lung adenocarcinoma 7 | 2,716
Breast cancer 6 | 3,578
Cataract 6 | 297
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
lung cancer 6 | 4,740
non-small cell lung cancer 6 | 2,890
primitive neuroectodermal tumor 6 | 3,035
Autosomal recessive predisposition 5 | 1,442
Cancer 5 | 2,499
Clouston syndrome 5 | 9
Lens Opacities 5 | 231
Nonsyndromic deafness 5 | 142
Palmoplantar keratosis 5 | 74
diabetes mellitus 5 | 1,728
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Alopecia 4 | 115
Astrocytoma, Pilocytic 4 | 3,081
Conductive hearing loss 4 | 123
Deafness, autosomal recessive 1A 4 | 4
Dull intelligence 4 | 645
Erythema 4 | 58
Flushing 4 | 60
Frontal bossing 4 | 157
Hyperkeratosis, generalized 4 | 14
Hypertension 4 | 396
Hypertensive disease 4 | 292
Infantile onset 4 | 238
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Schizophrenia 4 | 1,160
Sensorineural hearing loss 4 | 106
Small head 4 | 374
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pancreatic cancer 4 | 2,398
spina bifida 4 | 1,074
Aortic coarctation 3 | 30
Autistic Disorder 3 | 364
Bart-Pumphrey syndrome 3 | 4
Bilateral fifth finger clinodactyly 3 | 110
Cerebrovascular disease 3 | 238
Charcot-Marie-Tooth disease 3 | 62
Curvature of little finger 3 | 110
DEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder) 3 | 3
Deafness 3 | 198
Dystrophic fingernails 3 | 18
Enlarged vestibular aqueduct 3 | 10
Epilepsy 3 | 792
Fine hair 3 | 42
Isolated cases 3 | 72
Kidney cancer 3 | 2,613
Low Vision 3 | 174
MEDNIK syndrome 3 | 8
Myopia 3 | 176
Nail dysplasia 3 | 52
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Nuclear cataract 3 | 19
Nuclear non-senile cataract 3 | 18
Patent ductus arteriosus 3 | 90
Sensorineural Hearing Loss (disorder) 3 | 284
Short stature 3 | 531
Skin Neoplasms 3 | 69
Sparse eyelashes 3 | 31
Sparse hair 3 | 59
Thin lips 3 | 49
Thin, sparse hair 3 | 59
Visual Impairment 3 | 174
X- linked recessive 3 | 110
breast carcinoma 3 | 1,638
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
pituitary cancer 3 | 1,972
Absence of eyebrows 2 | 31
Aplasia/Hypoplasia of the eyebrow 2 | 31
Downward slant of palpebral fissure 2 | 158
Dystrophia unguium 2 | 53
Photodysphoria 2 | 121
Photophobia 2 | 121
Sparse or absent eyebrows 2 | 31
Sparse/absent eyebrows 2 | 31

Tissue

Endocrine System 27 | 18,159
Female tissues 24 | 17,400
Urinary Tract 24 | 16,678
Digestive Tract 23 | 17,369
Liver and Pancreas 23 | 16,750
Nervous System 22 | 16,725
Skin and soft tissues 22 | 17,230
Blood and immune system 21 | 16,909
Male tissues 21 | 17,142
Respiratory system 19 | 16,393
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 24 | 12,091
Ion Channel 3 | 344

UniProt Keyword

Gap junction 27 | 27
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pannexin-3 PANX3 Tbio Ion Channel -1.66465 45.0 71
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Pannexin-2 PANX2 Tbio Ion Channel -1.77864 56.1 126
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Gap junction alpha-4 protein GJA4 Tbio Non-IDG -2.27043 180.6 231
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Gap junction beta-3 protein GJB3 Tbio Non-IDG -2.13572 133.9 212