Development Level

Tbio 17 | 10,625
Tdark 8 | 7,003

IMPC Phenotype

preweaning lethality, complete... 5 | 633
decreased bone mineral content 1 | 157
decreased lean body mass 1 | 195
hydroencephaly 1 | 6
increased circulating choleste... 1 | 53
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
prenatal lethality prior to he... 1 | 64

Disease

osteosarcoma 12 | 7,933
ovarian cancer 11 | 8,491
Intellectual disability 8 | 573
lung cancer 8 | 4,473
medulloblastoma, large-cell 7 | 6,234
psoriasis 6 | 6,685
Breast cancer 5 | 3,098
atypical teratoid / rhabdoid tumor 5 | 4,369
glioblastoma 5 | 5,572
Paroxysmal nocturnal hemoglobinuria 4 | 11
Epilepsy 3 | 346
Iridogoniodysgenesis syndrome 3 | 8
Multiple myeloma 3 | 1,327
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
primitive neuroectodermal tumor 3 | 3,031
tuberculosis 3 | 1,563
Hemoglobinuria, Paroxysmal 2 | 2
Pick disease 2 | 1,893
Proteinuria 2 | 63
West Syndrome 2 | 24
acute myeloid leukemia 2 | 785
aldosterone-producing adenoma 2 | 664
astrocytic glioma 2 | 2,241
colon cancer 2 | 1,475
cutaneous lupus erythematosus 2 | 1,056
diabetes mellitus 2 | 1,663
ependymoma 2 | 2,514
group 3 medulloblastoma 2 | 2,254
hepatocellular carcinoma 2 | 550
lung carcinoma 2 | 2,844
malignant mesothelioma 2 | 3,163
posterior fossa group B ependymoma 2 | 1,530
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 2,087
3-methylglutaconic aciduria 1 | 29
Acquired metabolic disease 1 | 267
Acute conjunctivitis 1 | 4
Alpha 1-antitrypsin deficiency 1 | 10
Amyotrophic lateral sclerosis type 1 1 | 22
Amyotrophic lateral sclerosis type 3 1 | 15
Anemia 1 | 252
Autoimmune thrombocytopenic purpura 1 | 14
Babesiosis 1 | 13
Bipolar Disorder 1 | 266
Chromosome 17q12 deletion syndrome 1 | 16
Coloboma 1 | 52
Congenital diaphragmatic hernia 1 | 44
Congenital disorder of glycosylation 1 | 53
Congenital muscular dystrophy 1 | 25
Congenital myasthenic syndrome 1 | 28
Down syndrome 1 | 548
Early infantile epileptic encephalopathy with suppression bursts 1 | 18
Friedreich ataxia 1 | 23
Fungal meningitis 1 | 7
Gastroparesis 1 | 20
Glomerulonephritis 1 | 36
Hirschsprung's disease 1 | 44
Hyperphosphatasia with mental retardation syndrome 1 1 | 1
Hyperphosphatasia with mental retardation syndrome 3 1 | 1
Hyperphosphatasia with mental retardation syndrome 6 1 | 1
IGA Glomerulonephritis 1 | 454
Intracranial aneurysm 1 | 20
Lassa fever 1 | 10
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 17 1 | 1
Malaria 1 | 140
Melanoma 1 | 261
Muscle Weakness 1 | 92
Ohtahara syndrome 1 | 4
Paget's disease of bone 1 | 28
Prostatic Neoplasms 1 | 471
Seizures 1 | 95
Sudden infant death syndrome 1 | 34
Urinary bladder cancer 1 | 34
Venous Thrombosis 1 | 21
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
adult high grade glioma 1 | 2,148
astrocytoma 1 | 1,493
breast carcinoma 1 | 1,614
chronic rhinosinusitis 1 | 512
esophageal adenocarcinoma 1 | 737
gastric carcinoma 1 | 832
interstitial lung disease 1 | 292
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
juvenile dermatomyositis 1 | 1,189
medulloblastoma 1 | 1,524
non-small cell lung cancer 1 | 2,798
oligodendroglioma 1 | 2,849
pancreatic cancer 1 | 2,300
pediatric high grade glioma 1 | 2,712
pilocytic astrocytoma 1 | 3,086
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 1,511
pre-eclampsia 1 | 67
primary pancreatic ductal adenocarcinoma 1 | 1,271
sonic hedgehog group medulloblastoma 1 | 1,482
tuberculosis and treatment for 3 months 1 | 327
tuberculosis and treatment for 6 months 1 | 686
urothelial carcinoma 1 | 318

Tissue

Skin and soft tissues 24 | 18,114
Blood and immune system 23 | 17,994
Cardiovascular System 23 | 17,957
Digestive Tract 23 | 18,472
Endocrine System 23 | 18,511
Female tissues 23 | 18,646
Liver and Pancreas 23 | 18,135
Male tissues 23 | 17,968
Nervous System 23 | 18,560
Respiratory system 23 | 17,483
Urinary Tract 23 | 18,443

Target Family

Enzyme 17 | 4,146
Non-IDG 8 | 11,969

UniProt Keyword

GPI-anchor biosynthesis 25 | 25
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine-threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GPI transamidase component PIG-S PIGS Tdark Enzyme -0.19189 1.54 61
Glycosylphosphatidylinositol anchor attachment 1 protein GPAA1 Tbio Non-IDG -1.51643 31.7 101
GPI ethanolamine phosphate transferase 1 PIGN Tbio Enzyme -1.90146 80.7 41
Phosphatidylinositol glycan anchor biosynthesis class U protein PIGU Tbio Non-IDG -0.96763 9.25 14
GPI mannosyltransferase 1 PIGM Tbio Enzyme -1.53902 34.2 55
Phosphatidylinositol-glycan biosynthesis class F protein PIGF Tbio Non-IDG -1.87886 66.2 47
GPI transamidase component PIG-T PIGT Tbio Enzyme -1.83981 66.7 98
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P PIGP Tbio Enzyme -1.76322 56.9 59
GPI mannosyltransferase 3 PIGB Tbio Enzyme -1.32153 22.0 70
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C PIGC Tbio Enzyme -1.58438 37.3 32