Development Level

Tbio 99 | 10,625
Tchem 17 | 1,890
Tdark 17 | 7,003
Tclin 4 | 602

IMPC Phenotype

increased exploration in new e... 3 | 56
decreased body weight 2 | 174
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased eosinophil cell numb... 2 | 41
female infertility 2 | 34
increased blood urea nitrogen ... 2 | 44
preweaning lethality, incomple... 2 | 260
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal rib morphology 1 | 28
abnormal social-conspecific in... 1 | 3
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
corneal opacity 1 | 25
decreased basophil cell number 1 | 11
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged adrenal glands 1 | 3
enlarged heart 1 | 111
enlarged heart atrium 1 | 2
enlarged kidney 1 | 7
enlarged uterus 1 | 3
hydrometra 1 | 13
hypoactivity 1 | 89
increased circulating chloride... 1 | 43
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
irregularly shaped pupil 1 | 7
male infertility 1 | 62
polycystic kidney 1 | 9
preweaning lethality, complete... 1 | 633
small adrenal glands 1 | 15
small kidney 1 | 10

Disease

psoriasis 71 | 6,685
osteosarcoma 55 | 7,933
ovarian cancer 51 | 8,491
glioblastoma 47 | 5,572
lung adenocarcinoma 44 | 2,714
medulloblastoma, large-cell 44 | 6,234
lung carcinoma 42 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,289
non-small cell lung cancer 37 | 2,798
lung cancer 36 | 4,473
atypical teratoid / rhabdoid tumor 35 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,956
pilocytic astrocytoma 34 | 3,086
Cancer 33 | 2,346
malignant mesothelioma 32 | 3,163
invasive ductal carcinoma 29 | 2,950
oligodendroglioma 29 | 2,849
cystic fibrosis 28 | 1,670
interstitial cystitis 28 | 2,299
pediatric high grade glioma 28 | 2,712
pituitary cancer 27 | 1,972
ductal carcinoma in situ 26 | 1,745
pancreatic cancer 26 | 2,300
primitive neuroectodermal tumor 26 | 3,031
Breast cancer 23 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,988
tuberculosis 22 | 1,563
adult high grade glioma 20 | 2,148
breast carcinoma 20 | 1,614
ulcerative colitis 20 | 2,087
subependymal giant cell astrocytoma 19 | 2,287
cutaneous lupus erythematosus 18 | 1,056
group 4 medulloblastoma 18 | 1,875
astrocytic glioma 17 | 2,241
ependymoma 17 | 2,514
Carcinoma 15 | 2,147
active Crohn's disease 15 | 918
group 3 medulloblastoma 15 | 2,254
posterior fossa group B ependymoma 15 | 1,530
Atopic dermatitis 14 | 944
astrocytoma 14 | 1,493
esophageal adenocarcinoma 14 | 737
primary pancreatic ductal adenocarcinoma 14 | 1,271
colon cancer 13 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
nasopharyngeal carcinoma 12 | 1,056
posterior fossa group A ependymoma 12 | 1,511
adrenocortical carcinoma 11 | 1,427
atypical teratoid/rhabdoid tumor 11 | 1,095
non-small cell lung carcinoma 11 | 413
active ulcerative colitis 10 | 477
diabetes mellitus 10 | 1,663
sonic hedgehog group medulloblastoma 10 | 1,482
Multiple Sclerosis 9 | 498
Rheumatoid Arthritis 9 | 1,170
gastric carcinoma 9 | 832
medulloblastoma 9 | 1,524
mucosa-associated lymphoid tissue lymphoma 8 | 480
spina bifida 8 | 1,064
Alzheimer's disease 7 | 644
Anemia 7 | 252
Autistic Disorder 7 | 320
Duchenne muscular dystrophy 7 | 602
Pick disease 7 | 1,893
Schizophrenia 7 | 503
Vascular disease 7 | 281
fibroadenoma 7 | 557
primary Sjogren syndrome 7 | 788
Down syndrome 6 | 548
Endometriosis 6 | 535
Obesity 6 | 616
dermatomyositis 6 | 966
hepatocellular carcinoma 6 | 550
juvenile dermatomyositis 6 | 1,189
nephrosclerosis 6 | 329
Prostatic Neoplasms 5 | 471
Proteinuria 5 | 63
Simpson-Golabi-Behmel syndrome 5 | 17
aldosterone-producing adenoma 5 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
head and neck cancer 5 | 270
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
Acquired metabolic disease 4 | 267
Atherosclerosis 4 | 275
Attention deficit hyperactivity disorder 4 | 156
Barrett's esophagus 4 | 185
Cognitive disorder 4 | 44
Craniofacial Abnormalities 4 | 147
Hydrolethalus syndrome 4 | 128
Hypersensitivity reaction type II disease 4 | 235
Juvenile arthritis 4 | 124
Liver disease 4 | 219
Parkinson's disease 4 | 364
Spontaneous abortion 4 | 108
Stomach Neoplasms 4 | 282
Thrombocytopenia 4 | 105
Toxic encephalopathy 4 | 131
interstitial lung disease 4 | 292
tuberculosis and treatment for 6 months 4 | 686
urothelial carcinoma 4 | 318

Tissue

Digestive Tract 133 | 18,472
Female tissues 133 | 18,646
Nervous System 133 | 18,560
Endocrine System 132 | 18,511
Male tissues 130 | 17,968
Skin and soft tissues 130 | 18,114
Urinary Tract 130 | 18,443
Blood and immune system 129 | 17,994
Liver and Pancreas 129 | 18,135
Cardiovascular System 124 | 17,957
Respiratory system 122 | 17,483

Target Family

Non-IDG 107 | 11,969
Enzyme 29 | 4,146
Kinase 1 | 634

UniProt Keyword

GPI-anchor 137 | 137
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine-threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Cryptic protein CFC1 Tbio Non-IDG -1.86644 61.8 97
Prostate stem cell antigen PSCA Tbio Non-IDG -2.37806 257.9 258
Folate receptor beta FOLR2 Tchem Non-IDG -1.86286 82.1 165
Matrix metalloproteinase-17 MMP17 Tchem Enzyme -1.37824 25.2 183
Sperm-egg fusion protein Juno IZUMO1R Tbio Non-IDG -1.71187 46.1 209
Vascular non-inflammatory molecule 3 VNN3 Tdark Non-IDG -0.65866 4.63 61
Trehalase TREH Tchem Enzyme -2.10744 136.5 46
Testis-expressed sequence 101 protein TEX101 Tbio Non-IDG -1.34385 21.6 24
GDNF family receptor alpha-3 GFRA3 Tbio Non-IDG -0.78010 5.03 164