Development Level

Tbio 108 | 11,445
Tdark 14 | 6,588
Tchem 13 | 1,598
Tclin 4 | 613

IMPC Phenotype

abnormal behavior 5 | 298
preweaning lethality, incomple... 5 | 499
abnormal heart morphology 3 | 162
enlarged heart 3 | 210
preweaning lethality, complete... 3 | 979
decreased body weight 2 | 161
decreased circulating glucose ... 2 | 126
hydrometra 2 | 53
increased blood urea nitrogen ... 2 | 48
increased circulating triglyce... 2 | 42
increased lean body mass 2 | 172
small testis 2 | 58
abnormal allantois morphology 1 | 8
abnormal anxiety-related respo... 1 | 1
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal left-right axis patte... 1 | 2
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal tail bud morphology 1 | 8
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
cataract 1 | 92
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged adrenal glands 1 | 3
enlarged heart atrium 1 | 4
enlarged kidney 1 | 14
enlarged uterus 1 | 11
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased circulating chloride... 1 | 41
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
irregularly shaped pupil 1 | 7
pale yolk sac 1 | 25
pallor 1 | 34
polycystic kidney 1 | 15
scaly skin 1 | 4
short tibia 1 | 97
small adrenal glands 1 | 16
small kidney 1 | 16
small superior vagus ganglion 1 | 74
thick skin 1 | 4

Disease

Carcinoma 71 | 11,493
psoriasis 71 | 6,694
osteosarcoma 55 | 7,950
ovarian cancer 51 | 8,520
glioblastoma 48 | 5,792
adult high grade glioma 44 | 3,801
lung adenocarcinoma 44 | 2,716
medulloblastoma, large-cell 44 | 6,241
atypical teratoid / rhabdoid tumor 42 | 5,112
lung carcinoma 42 | 2,843
non-small cell lung cancer 42 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
lung cancer 38 | 4,740
Astrocytoma, Pilocytic 36 | 3,081
ependymoma 36 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
Cancer 34 | 2,499
malignant mesothelioma 32 | 3,232
group 3 medulloblastoma 30 | 4,104
oligodendroglioma 30 | 2,850
cystic fibrosis 29 | 1,696
interstitial cystitis 29 | 2,312
invasive ductal carcinoma 29 | 2,951
pituitary cancer 28 | 1,972
Breast cancer 27 | 3,578
pancreatic cancer 27 | 2,398
ductal carcinoma in situ 26 | 1,745
primitive neuroectodermal tumor 26 | 3,035
tuberculosis 26 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
astrocytic glioma 21 | 2,597
breast carcinoma 20 | 1,638
group 4 medulloblastoma 19 | 1,855
subependymal giant cell astrocytoma 19 | 2,287
ulcerative colitis 19 | 1,819
cutaneous lupus erythematosus 18 | 1,057
Schizophrenia 17 | 1,160
active Crohn's disease 16 | 922
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Kidney cancer 15 | 2,613
Atopic dermatitis 14 | 952
esophageal adenocarcinoma 14 | 737
active ulcerative colitis 13 | 764
colon cancer 13 | 1,478
nasopharyngeal carcinoma 12 | 1,058
adrenocortical carcinoma 11 | 1,428
primary pancreatic ductal adenocarcinoma 11 | 1,109
Autosomal recessive predisposition 10 | 1,442
Liver Cirrhosis, Experimental 10 | 769
Rheumatoid arthritis 10 | 1,191
astrocytoma 10 | 1,146
diabetes mellitus 10 | 1,728
spina bifida 10 | 1,074
Anemia 9 | 365
Multiple Sclerosis 9 | 540
Alzheimer's disease 8 | 658
Bipolar Disorder 8 | 666
mucosa-associated lymphoid tissue lymphoma 8 | 484
Autistic Disorder 7 | 364
Duchenne muscular dystrophy 7 | 601
Pick disease 7 | 1,894
Type 2 diabetes mellitus 7 | 272
Vascular disease 7 | 319
fibroadenoma 7 | 559
gastric carcinoma 7 | 807
primary Sjogren syndrome 7 | 735
Acquired metabolic disease 6 | 336
Alcoholic Intoxication, Chronic 6 | 289
Down syndrome 6 | 499
Endometriosis 6 | 540
dermatomyositis 6 | 966
hepatocellular carcinoma 6 | 547
juvenile dermatomyositis 6 | 1,187
nephrosclerosis 6 | 333
non-small cell lung carcinoma 6 | 317
Epilepsy 5 | 792
Kidney disease 5 | 430
Mal de Meleda 5 | 7
Obesity 5 | 678
Prostatic Neoplasms 5 | 495
Seizures 5 | 596
Simpson-Golabi-Behmel syndrome 5 | 19
aldosterone-producing adenoma 5 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
head and neck cancer 5 | 271
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
Abortion, Spontaneous 4 | 109
Arthritis, Juvenile 4 | 126
Atherosclerosis 4 | 291
Attention deficit hyperactivity disorder 4 | 278
Broad flat nasal bridge 4 | 236
Cognitive disorder 4 | 50
Juvenile arthritis 4 | 126
Major Depressive Disorder 4 | 301
Nasal bridge wide 4 | 236
Spontaneous abortion 4 | 113
Stomach Neoplasms 4 | 300
Unipolar Depression 4 | 250
pediatric high grade glioma 4 | 1,064
urothelial carcinoma 4 | 318

Tissue

Endocrine System 135 | 18,159
Digestive Tract 133 | 17,369
Female tissues 129 | 17,400
Skin and soft tissues 127 | 17,230
Male tissues 125 | 17,142
Blood and immune system 123 | 16,909
Liver and Pancreas 123 | 16,750
Nervous System 121 | 16,725
Urinary Tract 120 | 16,678
Respiratory system 115 | 16,393
Cardiovascular System 99 | 15,192

Target Family

Non-IDG 109 | 12,091
Enzyme 29 | 4,145
Kinase 1 | 634

UniProt Keyword

GPI-anchor 139 | 139
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cryptic protein CFC1 Tbio Non-IDG -1.89131 76.4 159
Ephrin-A3 EFNA3 Tbio Non-IDG -1.53049 26.8 219
Ephrin-A4 EFNA4 Tbio Non-IDG -1.23647 17.4 213
Testis-expressed protein 101 TEX101 Tbio Non-IDG -1.34939 22.8 30
Shadow of prion protein SPRN Tbio Non-IDG -2.49698 315.1 88
Beta-tectorin TECTB Tbio Non-IDG -1.23705 16.8 72
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
UL-16 binding protein 5 RAET1G Tbio Non-IDG -0.77225 5.67 20
Lymphocyte antigen 6H LY6H Tdark Non-IDG -0.76039 4.88 44
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314