Development Level

Tbio 73 | 10,625
Tchem 27 | 1,890
Tdark 12 | 7,003
Tclin 10 | 602

IMPC Term

preweaning lethality, complete... 8 | 633
embryonic lethality prior to o... 4 | 148
abnormal embryo size 3 | 112
abnormal behavior 2 | 226
abnormal epididymis morphology 2 | 31
increased circulating sodium l... 2 | 71
increased mean corpuscular hem... 2 | 93
small kidney 2 | 10
abnormal coat/hair pigmentatio... 1 | 54
abnormal digit morphology 1 | 13
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal jejunum morphology 1 | 1
abnormal lens morphology 1 | 73
abnormal lumbar vertebrae morp... 1 | 6
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal sacral vertebrae morp... 1 | 5
abnormal skin appearance 1 | 8
abnormal stomach morphology 1 | 4
abnormal tail bud morphology 1 | 6
abnormal testis morphology 1 | 30
abnormal vitreous body morphol... 1 | 7
abnormal vocalization 1 | 21
anophthalmia 1 | 20
craniofacial phenotype 1 | 9
decreased KLRG1-positive CD4-p... 1 | 1
decreased Ly6C low monocyte nu... 1 | 23
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating calcium ... 1 | 33
decreased circulating thyroxin... 1 | 5
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased monocyte cell number 1 | 28
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased circulating free fat... 1 | 17
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased sacral vertebrae num... 1 | 62
increased spleen weight 1 | 3
increased startle reflex 1 | 38
microphthalmia 1 | 15
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11

Disease

osteosarcoma 58 | 7,933
ovarian cancer 58 | 8,484
psoriasis 50 | 6,685
pancreatic ductal adenocarcinoma liver metastasis 41 | 1,795
medulloblastoma, large-cell 39 | 6,234
glioblastoma 34 | 5,572
lung cancer 34 | 4,466
non-small cell lung cancer 33 | 2,798
invasive ductal carcinoma 29 | 2,950
lung carcinoma 27 | 2,844
malignant mesothelioma 27 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
atypical teratoid / rhabdoid tumor 23 | 4,369
lung adenocarcinoma 21 | 2,713
pilocytic astrocytoma 21 | 3,086
ulcerative colitis 21 | 2,087
ductal carcinoma in situ 20 | 1,745
interstitial cystitis 20 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,988
Breast cancer 19 | 3,094
adrenocortical carcinoma 19 | 1,427
breast carcinoma 18 | 1,614
adult high grade glioma 16 | 2,148
pancreatic cancer 16 | 2,300
Pick disease 15 | 1,893
pituitary cancer 15 | 1,972
subependymal giant cell astrocytoma 15 | 2,287
oligodendroglioma 14 | 2,849
Multiple acyl-CoA dehydrogenase deficiency 13 | 26
active Crohn's disease 13 | 918
colon cancer 13 | 1,475
cystic fibrosis 13 | 1,665
diabetes mellitus 13 | 1,663
group 3 medulloblastoma 13 | 2,254
group 4 medulloblastoma 13 | 1,875
pediatric high grade glioma 13 | 2,712
posterior fossa group A ependymoma 13 | 1,511
primitive neuroectodermal tumor 13 | 3,031
astrocytic glioma 12 | 2,241
posterior fossa group B ependymoma 12 | 1,530
sonic hedgehog group medulloblastoma 12 | 1,482
tuberculosis 12 | 1,557
atypical teratoid/rhabdoid tumor 11 | 1,095
Cancer 10 | 2,346
Obesity 10 | 616
Schizophrenia 10 | 501
ependymoma 10 | 2,514
nasopharyngeal carcinoma 10 | 1,056
aldosterone-producing adenoma 9 | 664
cutaneous lupus erythematosus 9 | 1,056
gastric carcinoma 9 | 832
nephrosclerosis 9 | 329
Autistic Disorder 8 | 320
Diabetes Mellitus, Experimental 8 | 106
Hypertension 8 | 287
Kidney disease 8 | 396
Leigh disease 8 | 81
Multiple myeloma 8 | 1,327
Prostatic Neoplasms 8 | 471
Rheumatoid Arthritis 8 | 1,160
medulloblastoma 8 | 1,524
Atherosclerosis 7 | 275
Methylmalonic acidemia 7 | 39
acute quadriplegic myopathy 7 | 1,157
astrocytoma 7 | 1,493
spina bifida 7 | 1,064
Alzheimer's disease 6 | 644
Atopic dermatitis 6 | 944
IGA Glomerulonephritis 6 | 454
Isovaleric acidemia 6 | 14
Mammary Neoplasms 6 | 410
Maple syrup urine disease 6 | 25
Toxic encephalopathy 6 | 131
beta-ketothiolase deficiency 6 | 13
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 557
inflammatory breast cancer 6 | 404
Bipolar Disorder 5 | 266
Cerebrovascular disease 5 | 231
Colonic Neoplasms 5 | 126
Colorectal Neoplasms 5 | 217
Degenerative polyarthritis 5 | 93
Endometriosis 5 | 535
Heart disease 5 | 279
Heart failure 5 | 80
Homocystinuria 5 | 23
Propionic acidemia 5 | 20
Stomach Neoplasms 5 | 282
Systemic primary carnitine deficiency disease 5 | 16
nervous system disorder 5 | 53
non primary Sjogren syndrome sicca 5 | 840
pancreatic carcinoma 5 | 567
primary Sjogren syndrome 5 | 789
primary pancreatic ductal adenocarcinoma 5 | 1,271
progressive supranuclear palsy 5 | 674
Brain Ischemia 4 | 87
Contact Dermatitis 4 | 80
mucosa-associated lymphoid tissue lymphoma 4 | 480
non diabetic and post-ischemic heart failure 4 | 200

Tissue

Blood and immune system 121 | 17,995
Cardiovascular System 121 | 17,958
Digestive Tract 121 | 18,473
Endocrine System 121 | 18,512
Female tissues 121 | 18,647
Liver and Pancreas 121 | 18,136
Nervous System 121 | 18,561
Urinary Tract 121 | 18,444
Male tissues 120 | 17,969
Respiratory system 120 | 17,484
Skin and soft tissues 120 | 18,115

Target Family

Enzyme 108 | 4,146
Non-IDG 11 | 11,971
Epigenetic 2 | 242
Ion Channel 1 | 341

UniProt Keyword

Flavoprotein 122 | 122
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dimethylaniline monooxygenase [N-oxide-forming] 5 FMO5 Tbio Enzyme -0.93021 9.11 128
Lysine-specific histone demethylase 1B KDM1B Tbio Epigenetic -1.39308 24.2 69
FAD-dependent oxidoreductase domain-containing protein 2 FOXRED2 Tdark Enzyme -0.17609 2.34 58
Choline dehydrogenase, mitochondrial CHDH Tbio Enzyme -1.38953 24.8 68
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.32560 2206.3 649
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM Tbio Enzyme -2.58670 387.0 269
Cryptochrome-2 CRY2 Tbio Non-IDG -2.33124 215.9 131
Metalloreductase STEAP2 STEAP2 Tbio Enzyme -1.70084 48.5 131
Peroxisomal acyl-coenzyme A oxidase 3 ACOX3 Tdark Enzyme -1.21608 14.6 47
NADH-cytochrome b5 reductase 3 CYB5R3 Tchem Enzyme -1.93440 89.2 241