Development Level

Tbio 31 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

decreased circulating glucose ... 2 | 126
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal gait 1 | 69
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased circulating chloride... 1 | 41
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 18 | 11,493
psoriasis 15 | 6,694
medulloblastoma, large-cell 9 | 6,241
ependymoma 8 | 4,679
osteosarcoma 8 | 7,950
Infertility 7 | 188
glioblastoma 7 | 5,792
Astrocytoma, Pilocytic 6 | 3,081
atypical teratoid / rhabdoid tumor 5 | 5,112
Cancer 4 | 2,499
Diphtheria 4 | 40
Male infertility 4 | 206
Oophoritis 4 | 10
Ovarian dysfunction 4 | 18
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
ovarian cancer 4 | 8,520
Autosomal recessive predisposition 3 | 1,442
cutaneous lupus erythematosus 3 | 1,057
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Glaucoma 2 | 239
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
Schizophrenia 2 | 1,160
Toxic encephalopathy 2 | 141
colon cancer 2 | 1,478
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Age related macular degeneration 1 | 72
Amyotrophic Lateral Sclerosis, Guam Form 1 | 2
Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1 1 | 2
Anxiety 1 | 136
Anxiety disease 1 | 113
Azoospermia 1 | 110
Brain disease 1 | 96
Bronchitis, Chronic 1 | 12
Bulimia nervosa 1 | 14
Carcinoma, Non-Small-Cell Lung 1 | 107
Celiac disease 1 | 116
Ciliary Motility Disorders 1 | 38
Creutzfeldt-Jakob disease 1 | 21
Diabetes Mellitus, Experimental 1 | 108
Enophthalmos 1 | 75
Fatal familial insomnia 1 | 10
Hereditary spherocytosis type 4 1 | 18
Hodgkin's lymphoma 1 | 15
Irritable Mood 1 | 1
Kartagener Syndrome 1 | 38
Learning disability 1 | 17
Leber congenital amaurosis 1 1 | 6
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Multiple system atrophy 1 | 29
Muscle Rigidity 1 | 49
Nasal inflammation 1 | 7
Neoplasms, Germ Cell and Embryonal 1 | 15
Ocular hypertension 1 | 42
Otosclerosis 1 | 15
Parkinsonian Disorders 1 | 56
Premature ovarian failure 1 | 65
Primary ciliary dyskinesia 1 | 76
Recurrent otitis media 1 | 42
Recurrent sinus disease 1 | 22
Recurrent sinusitis 1 | 22
Respiratory insufficiency due to defective ciliary clearance 1 | 6
Resting Tremor 1 | 9
Rhinitis 1 | 54
Scrapie 1 | 17
Theileriasis 1 | 13
Variant Creutzfeldt-Jakob disease 1 | 16
Velocardiofacial syndrome 1 | 46
cataract 14 multiple types 1 | 5
interstitial lung disease 1 | 298
non-inflammatory breast cancer 1 | 66
non-small cell lung carcinoma 1 | 317
rhinitis with controlled asthma 1 | 8

Tissue

Endocrine System 35 | 18,159
Male tissues 32 | 17,142
Skin and soft tissues 29 | 17,230
Female tissues 28 | 17,400
Digestive Tract 27 | 17,369
Blood and immune system 26 | 16,909
Nervous System 26 | 16,725
Urinary Tract 26 | 16,678
Liver and Pancreas 25 | 16,750
Cardiovascular System 23 | 15,192
Respiratory system 23 | 16,393

Target Family

Non-IDG 24 | 12,091
Enzyme 10 | 4,145
Transporter 1 | 473
oGPCR 1 | 421

UniProt Keyword

Fertilization 36 | 36
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sperm-associated antigen 8 SPAG8 Tbio Non-IDG -0.96272 9.29 158
Zona pellucida sperm-binding protein 4 ZP4 Tbio Non-IDG -2.12217 132.1 123
Beta-defensin 126 DEFB126 Tbio Non-IDG -1.32124 21.5 11
Sperm-egg fusion protein Juno IZUMO1R Tbio Non-IDG -1.78804 57.0 212
Membrane cofactor protein CD46 Tbio Non-IDG -2.94025 875.6 770
Prion-like protein doppel PRND Tbio Non-IDG -2.49819 344.5 33
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.19402 16.8 65
Sperm mitochondrial-associated cysteine-rich protein SMCP Tbio Non-IDG -1.98218 96.6 133
Epididymal sperm-binding protein 1 ELSPBP1 Tbio Non-IDG -1.16386 14.3 58
Sperm-associated antigen 1 SPAG1 Tbio Non-IDG -2.00381 97.1 110