Development Level

Tbio 73 | 10,625
Tchem 34 | 1,890
Tdark 14 | 7,003
Tclin 3 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, incomple... 5 | 260
decreased total body fat amoun... 4 | 186
decreased lean body mass 3 | 195
increased mean corpuscular hem... 3 | 93
abnormal locomotor activation 2 | 26
decreased body length 2 | 108
decreased body weight 2 | 174
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
enlarged spleen 2 | 26
increased circulating bilirubi... 2 | 16
increased circulating phosphat... 2 | 24
increased mean platelet volume 2 | 19
increased red blood cell distr... 2 | 21
limb grasping 2 | 35
abnormal behavioral response t... 1 | 52
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal tibia morphology 1 | 14
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
anophthalmia 1 | 20
corneal opacity 1 | 25
decreased CD5-positive Ly6C-po... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased T cell number 1 | 31
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased startle reflex 1 | 48
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
hydrometra 1 | 13
hypoactivity 1 | 89
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased effector memory T-he... 1 | 5
increased glycosylated hemoglo... 1 | 1
increased grip strength 1 | 83
increased heart rate 1 | 17
increased heart weight 1 | 37
increased memory-marker gamma-... 1 | 2
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
increased spleen weight 1 | 3
increased total body fat amoun... 1 | 57
preweaning lethality, complete... 1 | 633
shortened RR interval 1 | 19
small testis 1 | 37
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

ovarian cancer 62 | 8,484
osteosarcoma 53 | 7,933
psoriasis 52 | 6,685
medulloblastoma, large-cell 44 | 6,234
lung cancer 40 | 4,466
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,795
malignant mesothelioma 33 | 3,162
glioblastoma 31 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
ulcerative colitis 31 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
interstitial cystitis 29 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,956
invasive ductal carcinoma 27 | 2,950
non-small cell lung cancer 25 | 2,798
pancreatic cancer 25 | 2,300
lung carcinoma 24 | 2,844
Obesity 23 | 616
oligodendroglioma 23 | 2,849
ductal carcinoma in situ 21 | 1,745
Breast cancer 20 | 3,094
atypical teratoid / rhabdoid tumor 20 | 4,369
lung adenocarcinoma 19 | 2,713
astrocytoma 18 | 1,493
ependymoma 18 | 2,514
primitive neuroectodermal tumor 18 | 3,031
tuberculosis 18 | 1,557
adrenocortical carcinoma 17 | 1,427
colon cancer 17 | 1,475
subependymal giant cell astrocytoma 17 | 2,287
Pick disease 16 | 1,893
adult high grade glioma 16 | 2,148
group 4 medulloblastoma 16 | 1,875
pilocytic astrocytoma 16 | 3,086
Cancer 15 | 2,346
astrocytic glioma 15 | 2,241
Atopic dermatitis 14 | 944
Multiple myeloma 14 | 1,327
pediatric high grade glioma 14 | 2,712
active Crohn's disease 13 | 918
cystic fibrosis 13 | 1,665
diabetes mellitus 13 | 1,663
Rheumatoid Arthritis 12 | 1,160
group 3 medulloblastoma 12 | 2,254
pituitary cancer 11 | 1,972
primary pancreatic ductal adenocarcinoma 11 | 1,271
aldosterone-producing adenoma 10 | 664
posterior fossa group B ependymoma 10 | 1,530
Fatty liver disease 9 | 84
acute quadriplegic myopathy 9 | 1,157
posterior fossa group A ependymoma 9 | 1,511
progressive supranuclear palsy 9 | 674
Carnitine palmitoyltransferase II deficiency 8 | 16
Prostatic Neoplasms 8 | 471
atypical teratoid/rhabdoid tumor 8 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
breast carcinoma 8 | 1,614
nasopharyngeal carcinoma 8 | 1,056
pancreatic carcinoma 8 | 567
Carcinoma 7 | 2,147
Hypoglycemia 7 | 81
Liver carcinoma 7 | 217
Metabolic syndrome X 7 | 155
Neurodegenerative disease 7 | 383
Waldenstrons macroglobulinemia 7 | 765
Zellweger Syndrome 7 | 38
acute myeloid leukemia 7 | 780
dermatomyositis 7 | 933
esophageal adenocarcinoma 7 | 737
gastric carcinoma 7 | 832
primary Sjogren syndrome 7 | 789
spina bifida 7 | 1,064
Adrenoleukodystrophy 6 | 31
Alzheimer's disease 6 | 644
Asthma 6 | 349
Cerebrovascular disease 6 | 231
Down syndrome 6 | 548
Duchenne muscular dystrophy 6 | 602
Kidney disease 6 | 396
Mammary Neoplasms 6 | 410
Multiple acyl-CoA dehydrogenase deficiency 6 | 26
Peripheral Neuropathy 6 | 303
beta-ketothiolase deficiency 6 | 13
cutaneous lupus erythematosus 6 | 1,056
hereditary spastic paraplegia 6 | 313
medulloblastoma 6 | 1,524
non diabetic and post-ischemic heart failure 6 | 200
Coronary artery disease 5 | 240
Hypertension 5 | 287
Intellectual disability 5 | 573
Isovaleric acidemia 5 | 14
Lipid metabolism disorder 5 | 102
Methylmalonic acidemia 5 | 39
Propionic acidemia 5 | 20
Stomach Neoplasms 5 | 282
gastric cancer 5 | 430
juvenile dermatomyositis 5 | 1,189
nephrosclerosis 5 | 329
non primary Sjogren syndrome sicca 5 | 840
sonic hedgehog group medulloblastoma 5 | 1,482

Tissue

Blood and immune system 123 | 17,995
Cardiovascular System 123 | 17,958
Digestive Tract 123 | 18,473
Female tissues 123 | 18,647
Liver and Pancreas 123 | 18,136
Nervous System 123 | 18,561
Endocrine System 122 | 18,512
Male tissues 122 | 17,969
Respiratory system 122 | 17,484
Urinary Tract 122 | 18,444
Skin and soft tissues 121 | 18,115

Target Family

Enzyme 98 | 4,146
Non-IDG 16 | 11,971
Transporter 6 | 473
Kinase 4 | 634

UniProt Keyword

Fatty acid metabolism 124 | 124
Complete proteome 20,114 | 20,114
Reference proteome 20,114 | 20,114
Polymorphism 12,039 | 12,039
Alternative splicing 10,512 | 10,512
Phosphoprotein 8,194 | 8,194
Membrane 7,179 | 7,179
3D-structure 5,887 | 5,887
Transmembrane 5,214 | 5,214
Transmembrane helix 5,194 | 5,194
Nucleus 5,156 | 5,156
Repeat 4,899 | 4,899
Cytoplasm 4,782 | 4,782
Glycoprotein 4,612 | 4,612
Metal-binding 3,614 | 3,614
Signal 3,487 | 3,487
Disulfide bond 3,472 | 3,472
Acetylation 3,372 | 3,372
Cell membrane 3,182 | 3,182
Direct protein sequencing 2,852 | 2,852
Disease mutation 2,540 | 2,540
Transcription 2,375 | 2,375
Zinc 2,340 | 2,340
Transcription regulation 2,309 | 2,309
Coiled coil 2,142 | 2,142
DNA-binding 1,998 | 1,998
Transport 1,964 | 1,964
Secreted 1,941 | 1,941
Zinc-finger 1,784 | 1,784
Nucleotide-binding 1,769 | 1,769
Ubl conjugation 1,741 | 1,741
Hydrolase 1,640 | 1,640
Transferase 1,592 | 1,592
Receptor 1,496 | 1,496
ATP-binding 1,377 | 1,377
Cytoskeleton 1,130 | 1,130
Mitochondrion 1,115 | 1,115
Isopeptide bond 1,112 | 1,112
Endoplasmic reticulum 1,071 | 1,071
Methylation 962 | 962
Developmental protein 943 | 943
Transducer 886 | 886
Calcium 864 | 864
G-protein coupled receptor 830 | 830
Golgi apparatus 819 | 819
Lipoprotein 813 | 813
Cell projection 718 | 718
Cell junction 672 | 672
Ubl conjugation pathway 669 | 669
RNA-binding 663 | 663
Differentiation 661 | 661
Activator 657 | 657
Cell cycle 637 | 637
Kinase 637 | 637
Ion transport 628 | 628
Protein transport 604 | 604
Sensory transduction 600 | 600
Repressor 589 | 589
Immunity 571 | 571
Oxidoreductase 571 | 571
Immunoglobulin domain 546 | 546
Magnesium 543 | 543
Transit peptide 535 | 535
Protease 531 | 531
Apoptosis 529 | 529
Endosome 488 | 488
Cytoplasmic vesicle 487 | 487
Cell adhesion 482 | 482
Host-virus interaction 452 | 452
Signal-anchor 452 | 452
Olfaction 436 | 436
Lipid metabolism 427 | 427
Serine/threonine-protein kinas... 388 | 388
Cell division 372 | 372
Chromosome 361 | 361
Synapse 356 | 356
Ion channel 349 | 349
DNA damage 347 | 347
GTP-binding 338 | 338
Ligase 332 | 332
mRNA processing 326 | 326
Palmitate 322 | 322
Chromosomal rearrangement 320 | 320
Iron 318 | 318
Leucine-rich repeat 310 | 310
Mental retardation 299 | 299
Cleavage on pair of basic resi... 296 | 296
Neurodegeneration 292 | 292
DNA repair 288 | 288
Chromatin regulator 285 | 285
Ribonucleoprotein 280 | 280
Microtubule 279 | 279
WD repeat 278 | 278
Lysosome 275 | 275
Actin-binding 271 | 271
Mitochondrion inner membrane 268 | 268
Mitosis 262 | 262
ANK repeat 258 | 258
Extracellular matrix 258 | 258
Innate immunity 256 | 256
mRNA splicing 255 | 255

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.96515 948.2 132
Peroxisomal multifunctional enzyme type 2 HSD17B4 Tbio Non-IDG -2.15826 152.2 203
Fatty acid synthase FASN Tchem Enzyme -2.49948 348.5 388
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 HACD1 Tbio Enzyme -1.46870 28.7 59
Very-long-chain enoyl-CoA reductase TECR Tbio Enzyme -2.58601 380.5 85
Acyl-coenzyme A thioesterase 12 ACOT12 Tbio Enzyme -0.94659 8.55 79
Elongation of very long chain fatty acids protein 5 ELOVL5 Tchem Non-IDG -1.81279 72.3 189
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.30451 203.2 252
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.20847 1594.9 391
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM Tbio Enzyme -2.58670 387.0 269