Development Level

Tbio 77 | 11,445
Tchem 31 | 1,598
Tdark 13 | 6,588
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
decreased lean body mass 3 | 135
decreased lymphocyte cell numb... 3 | 83
increased mean platelet volume 3 | 45
increased monocyte cell number 3 | 63
increased red blood cell distr... 3 | 34
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased mean platelet volume 2 | 25
enlarged heart 2 | 210
enlarged spleen 2 | 41
hydrometra 2 | 53
hypoactivity 2 | 132
increased circulating bilirubi... 2 | 16
increased circulating phosphat... 2 | 26
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
preweaning lethality, complete... 2 | 979
small superior vagus ganglion 2 | 74
small testis 2 | 58
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal maxilla morphology 1 | 17
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal tibia morphology 1 | 14
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cataract 1 | 92
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
enlarged thymus 1 | 5
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased glycosylated hemoglo... 1 | 1
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Carcinoma 81 | 11,493
ovarian cancer 63 | 8,520
osteosarcoma 52 | 7,950
psoriasis 52 | 6,694
medulloblastoma, large-cell 44 | 6,241
lung cancer 40 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
malignant mesothelioma 33 | 3,232
glioblastoma 32 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
ependymoma 29 | 4,679
interstitial cystitis 29 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
atypical teratoid / rhabdoid tumor 27 | 5,112
invasive ductal carcinoma 27 | 2,951
group 3 medulloblastoma 26 | 4,104
Obesity 25 | 678
non-small cell lung cancer 25 | 2,890
pancreatic cancer 25 | 2,398
adult high grade glioma 24 | 3,801
lung carcinoma 24 | 2,843
Autosomal recessive predisposition 23 | 1,442
oligodendroglioma 23 | 2,850
ulcerative colitis 23 | 1,819
Breast cancer 22 | 3,578
ductal carcinoma in situ 21 | 1,745
tuberculosis 21 | 2,010
lung adenocarcinoma 19 | 2,716
primitive neuroectodermal tumor 18 | 3,035
adrenocortical carcinoma 17 | 1,428
astrocytic glioma 17 | 2,597
colon cancer 17 | 1,478
subependymal giant cell astrocytoma 17 | 2,287
Astrocytoma, Pilocytic 16 | 3,081
Cancer 16 | 2,499
Muscle hypotonia 16 | 571
Pick disease 16 | 1,894
astrocytoma 16 | 1,146
Kidney cancer 15 | 2,613
Atopic dermatitis 14 | 952
Multiple myeloma 14 | 1,332
Schizophrenia 14 | 1,160
cystic fibrosis 14 | 1,696
diabetes mellitus 14 | 1,728
active Crohn's disease 13 | 922
active ulcerative colitis 12 | 764
Rheumatoid arthritis 11 | 1,191
pituitary cancer 11 | 1,972
Fatty liver disease 10 | 103
aldosterone-producing adenoma 10 | 665
primary pancreatic ductal adenocarcinoma 10 | 1,109
Bipolar Disorder 9 | 666
Cognitive delay 9 | 608
Epilepsy 9 | 792
Global developmental delay 9 | 608
Hepatomegaly 9 | 285
Hypoglycemia 9 | 152
Mental and motor retardation 9 | 608
Seizures 9 | 596
acute quadriplegic myopathy 9 | 1,158
breast carcinoma 9 | 1,638
group 4 medulloblastoma 9 | 1,855
progressive supranuclear palsy 9 | 676
Failure to gain weight 8 | 365
Heart failure 8 | 162
Intellectual disability 8 | 1,016
Neurodegenerative disease 8 | 414
Pediatric failure to thrive 8 | 365
Prostatic Neoplasms 8 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
nasopharyngeal carcinoma 8 | 1,058
pancreatic carcinoma 8 | 562
Carcinoma, Hepatocellular 7 | 228
Carnitine palmitoyltransferase II deficiency 7 | 14
Elevated hepatic transaminases 7 | 81
Hepatic enzyme increased 7 | 81
Liver Cirrhosis, Experimental 7 | 769
Liver Dysfunction 7 | 99
Liver carcinoma 7 | 240
Liver enzymes abnormal 7 | 81
Liver function test increased 7 | 81
Liver function tests abnormal finding 7 | 81
Medium chain acyl-CoA dehydrogenase deficiency 7 | 13
Subclinical abnormal liver function tests 7 | 81
Transaminases increased 7 | 81
Very long chain acyl-CoA dehydrogenase deficiency 7 | 10
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 783
dermatomyositis 7 | 966
esophageal adenocarcinoma 7 | 737
gastric carcinoma 7 | 807
primary Sjogren syndrome 7 | 735
spina bifida 7 | 1,074
Alzheimer's disease 6 | 658
Down syndrome 6 | 499
Duchenne muscular dystrophy 6 | 601
Polycystic ovary syndrome 6 | 360
cutaneous lupus erythematosus 6 | 1,057
non diabetic and post-ischemic heart failure 6 | 200

Tissue

Digestive Tract 123 | 17,369
Endocrine System 123 | 18,159
Skin and soft tissues 123 | 17,230
Female tissues 121 | 17,400
Nervous System 121 | 16,725
Urinary Tract 121 | 16,678
Liver and Pancreas 120 | 16,750
Blood and immune system 119 | 16,909
Male tissues 119 | 17,142
Respiratory system 115 | 16,393
Cardiovascular System 113 | 15,192

Target Family

Enzyme 98 | 4,145
Non-IDG 16 | 12,091
Transporter 6 | 473
Kinase 4 | 634

UniProt Keyword

Fatty acid metabolism 124 | 124
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative fatty acid desaturase 2-like protein FADS2P1 FADS2P1 Tdark Enzyme 0.00000 0
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.98202 97.3 170
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OXSM Tbio Enzyme -1.82909 65.1 127
Bile acyl-CoA synthetase SLC27A5 Tbio Transporter -2.32176 196.8 181
S-acyl fatty acid synthase thioesterase, medium chain OLAH Tdark Enzyme -1.11894 12.1 39
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Long-chain-fatty-acid--CoA ligase 6 ACSL6 Tbio Enzyme -1.86749 73.8 139
Fatty acid desaturase 6 FADS6 Tdark Enzyme 0.48 0.18 0
Malonyl-CoA decarboxylase, mitochondrial MLYCD Tchem Enzyme -1.70434 46.1 67
Acetoacetyl-CoA synthetase AACS Tbio Enzyme -2.09428 127.1 97