Development Level

Tbio 24 | 11,445
Tchem 21 | 1,598
Tdark 4 | 6,588
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
decreased mean platelet volume 2 | 25
enlarged heart 2 | 210
enlarged spleen 2 | 41
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
preweaning lethality, complete... 2 | 979
abnormal lens morphology 1 | 81
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
anophthalmia 1 | 33
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
enlarged thymus 1 | 5
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating triglyce... 1 | 42
increased glycosylated hemoglo... 1 | 1
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
limb grasping 1 | 41
small testis 1 | 58

Disease

ovarian cancer 28 | 8,520
Carcinoma 27 | 11,493
psoriasis 26 | 6,694
osteosarcoma 24 | 7,950
medulloblastoma, large-cell 23 | 6,241
lung cancer 19 | 4,740
glioblastoma 18 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
malignant mesothelioma 18 | 3,232
group 3 medulloblastoma 17 | 4,104
oligodendroglioma 17 | 2,850
atypical teratoid / rhabdoid tumor 16 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
non-small cell lung cancer 16 | 2,890
pancreatic cancer 16 | 2,398
Breast cancer 15 | 3,578
ependymoma 15 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
lung carcinoma 15 | 2,843
interstitial cystitis 14 | 2,312
invasive ductal carcinoma 14 | 2,951
adult high grade glioma 13 | 3,801
lung adenocarcinoma 12 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
tuberculosis 12 | 2,010
Astrocytoma, Pilocytic 11 | 3,081
astrocytic glioma 11 | 2,597
ductal carcinoma in situ 11 | 1,745
primitive neuroectodermal tumor 11 | 3,035
subependymal giant cell astrocytoma 11 | 2,287
Cancer 10 | 2,499
Pick disease 10 | 1,894
Obesity 9 | 678
Schizophrenia 9 | 1,160
adrenocortical carcinoma 9 | 1,428
cystic fibrosis 9 | 1,696
Atopic dermatitis 8 | 952
colon cancer 8 | 1,478
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 1,819
breast carcinoma 7 | 1,638
diabetes mellitus 7 | 1,728
progressive supranuclear palsy 7 | 676
Heart failure 6 | 162
Kidney cancer 6 | 2,613
Multiple myeloma 6 | 1,332
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
acute quadriplegic myopathy 6 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
group 4 medulloblastoma 6 | 1,855
primary pancreatic ductal adenocarcinoma 6 | 1,109
Alzheimer's disease 5 | 658
Asthma 5 | 385
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
nasopharyngeal carcinoma 5 | 1,058
Breast Neoplasms 4 | 445
Carcinoma, Hepatocellular 4 | 228
Chemical and Drug Induced Liver Injury 4 | 195
Duchenne muscular dystrophy 4 | 601
Fatty liver disease 4 | 103
Heart disease 4 | 306
Hydrolethalus syndrome 4 | 128
Hypertension 4 | 396
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Liver carcinoma 4 | 240
Mammary Neoplasms 4 | 425
Neurodegenerative disease 4 | 414
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
Stomach Neoplasms 4 | 300
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
gastric carcinoma 4 | 807
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
Arthritis 3 | 290
Cerebrovascular accident 3 | 63
Cerebrovascular disease 3 | 238
Diarrhea 3 | 253
Fever 3 | 138
Kidney disease 3 | 430
Liver cancer 3 | 604
Migraine 3 | 83
Muscle hypotonia 3 | 571
Osteoarthritis 3 | 184
Pain agnosia 3 | 104
Patent ductus arteriosus 3 | 90
Urticaria 3 | 67
Waldenstrons macroglobulinemia 3 | 765
gastric cancer 3 | 459
juvenile dermatomyositis 3 | 1,187
non diabetic and post-ischemic heart failure 3 | 200
posterior fossa group A ependymoma 3 | 468
spina bifida 3 | 1,074

Tissue

Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Male tissues 51 | 17,142
Skin and soft tissues 51 | 17,230
Blood and immune system 50 | 16,909
Cardiovascular System 50 | 15,192
Liver and Pancreas 50 | 16,750
Nervous System 50 | 16,725
Respiratory system 50 | 16,393
Urinary Tract 50 | 16,678

Target Family

Enzyme 39 | 4,145
Non-IDG 9 | 12,091
Kinase 4 | 634

UniProt Keyword

Fatty acid biosynthesis 52 | 52
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OXSM Tbio Enzyme -1.82909 65.1 127
Putative fatty acid desaturase 2-like protein FADS2P1 FADS2P1 Tdark Enzyme 0.00000 0
S-acyl fatty acid synthase thioesterase, medium chain OLAH Tdark Enzyme -1.11894 12.1 39
Malonyl-CoA decarboxylase, mitochondrial MLYCD Tchem Enzyme -1.70434 46.1 67
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135
Fatty acid desaturase 6 FADS6 Tdark Enzyme 0.48 0.18 0
Elongation of very long chain fatty acids protein 1 ELOVL1 Tbio Non-IDG -1.29305 16.7 156
Elongation of very long chain fatty acids protein 5 ELOVL5 Tbio Non-IDG -1.90493 83.7 237
Very-long-chain enoyl-CoA reductase TECR Tbio Enzyme -2.64230 415.5 102
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122