Development Level

Tbio 16 | 11,651
Tdark 1 | 6,593

IMPC Phenotype

abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
enlarged uterus 1 | 11
increased bone mineral content 1 | 108
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Cataract 17 | 297
Nuclear cataract 11 | 19
Nuclear non-senile cataract 11 | 18
CATARACT 16, MULTIPLE TYPES 10 | 15
Congenital Bilateral Cataracts 8 | 50
Congenital cataract 8 | 50
Lens Opacities 8 | 231
Blindness 7 | 88
Myopia 7 | 176
Cataract microcornea syndrome 6 | 8
Cataract-microcornea syndrome 6 | 8
Corneal diameter decreased 6 | 47
Microcornea 6 | 47
Autosomal recessive predisposition 5 | 1,442
Carcinoma 5 | 11,493
Cataract, Pulverulent 5 | 11
Congenital total cataract 5 | 15
Presbyopia 5 | 20
cataract 2 multiple types 5 | 9
CATARACT, ANTERIOR POLAR 4 | 6
Lens subluxation 4 | 12
CATARACT, AUTOSOMAL DOMINANT 3 | 4
Cataract, congenital, cerulean type 1 3 | 4
Cerebrotendinous xanthomatosis 3 | 13
lung cancer 3 | 4,740
pituitary cancer 3 | 1,972
Alexander disease 2 | 11
Amblyopia 2 | 38
Autoimmune Diseases 2 | 67
CATARACT, COPPOCK-LIKE 2 | 2
Low Vision 2 | 174
Microphthalmia 2 | 76
Nystagmus 2 | 317
Uveitis 2 | 103
Visual Impairment 2 | 174
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Age related macular degeneration 1 | 72
Ainhum 1 | 4
Alpha-B Crystallinopathy 1 | 1
Anterior segment mesenchymal dysgenesis 1 | 7
Atypical autism 1 | 26
Autophagic vaculoes (finding) 1 | 3
CARDIOMYOPATHY, DILATED, 1II 1 | 1
CATARACT 12, MULTIPLE TYPES 1 | 1
CATARACT 17, MULTIPLE TYPES 1 | 1
CATARACT 23 1 | 1
CATARACT 23, MULTIPLE TYPES 1 | 1
CATARACT 42 1 | 1
Carcinoma, Squamous Cell 1 | 110
Cataract 8 multiple types 1 | 33
Cataract, Autosomal Dominant, Multiple Types 1 1 | 1
Cataract, Congenital Nuclear, Autosomal Recessive 3 1 | 1
Cataract, Congenital Zonular, with Sutural Opacities 1 | 1
Coloboma 1 | 51
Congenital aphakia 1 | 6
Congenital lamellar cataract 1 | 2
Cornea plana 1 | 12
Cortical cataract 1 | 1
Cryptosporidiosis 1 | 13
Cycloplegia 1 | 12
Diabetic retinopathy 1 | 56
EMG: myopathic abnormalities 1 | 22
Embryonal nuclear cataract (disorder) 1 | 3
Familial isolated dilated cardiomyopathy 1 | 41
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gestational choriocarcinoma 1 | 5
Hemophagocytic lymphohistiocytosis 1 | 30
Hypopituitarism 1 | 40
Hyporeflexia at ankle joints 1 | 2
Iris disease 1 | 10
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Late-onset proximal muscle weakness 1 | 2
Lisch epithelial corneal dystrophy 1 | 4
MYOPATHY, MYOFIBRILLAR, FATAL INFANTILE HYPERTONIC, ALPHA-B CRYSTALLIN-RELATED 1 | 1
Mitral regurgitation, mild 1 | 32
Mitral valve insufficiency 1 | 49
Muscle Rigidity 1 | 49
Muscle fiber splitting 1 | 7
Nephrogenic Diabetes Insipidus 1 | 16
Neurodegenerative Diseases 1 | 38
Neurofibromatosis 1 | 40
Peters anomaly 1 | 16
Posterior Y-sutural cataract 1 | 3
Posterior polar cataract 1 | 6
Primary cutaneous amyloidosis 1 | 29
Progressive cataract 1 | 1
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Reducing body myopathy 1 | 7
Respiratory Distress Syndrome, Adult 1 | 40
Respiratory insufficiency due to muscle weakness 1 | 37
Retinal vein occlusion 1 | 9
Tongue Neoplasms 1 | 8
Weak cry 1 | 17
dilated cardiomyopathy 1II 1 | 1

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Nervous System 12 | 16,725
Blood and immune system 10 | 16,909
Male tissues 10 | 17,142
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Urinary Tract 9 | 16,678
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Cardiovascular System 5 | 15,192

Target Family

Non-IDG 17 | 12,091

UniProt Keyword

Eye lens protein 17 | 17
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-crystallin A4 CRYBA4 Tbio Non-IDG -1.25788 15.5 105
Alpha-crystallin A chain CRYAA Tbio Non-IDG -2.84905 682.1 234
Phakinin BFSP2 Tbio Non-IDG -2.51557 325.7 81
Alpha-crystallin B chain CRYAB Tbio Non-IDG -2.29243 192.0 1100
Filensin BFSP1 Tbio Non-IDG -2.11395 128.7 179
Beta-crystallin B3 CRYBB3 Tbio Non-IDG -1.23297 18.1 101
Gamma-crystallin C CRYGC Tbio Non-IDG -2.28408 181.8 121
Gamma-crystallin D CRYGD Tbio Non-IDG -2.86961 731.4 164
Gamma-crystallin B CRYGB Tbio Non-IDG -2.22103 154.0 55
Beta-crystallin S CRYGS Tbio Non-IDG -2.79704 615.6 150